N-T-BOC-D-3-(2-NAPHTHYL)ALANINE
- Product Name
- N-T-BOC-D-3-(2-NAPHTHYL)ALANINE
- CAS No.
- 56583-58-5
- Chemical Name
- N-T-BOC-D-3-(2-NAPHTHYL)ALANINE
- Synonyms
- NALPHA-tert-Butoxycarbonyl-3-(2-naphthyl)-D-alanine;2-Naphthalenepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-
- CBNumber
- CB5497926
- Molecular Formula
- C18H21NO4
- Formula Weight
- 315.36
- MOL File
- 56583-58-5.mol
N-T-BOC-D-3-(2-NAPHTHYL)ALANINE Property
- storage temp.
- −20°C
- Appearance
- White to off-white Solid
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CHM0313009
- Product name
- 2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.41
- Updated
- 2021/12/16
- Product number
- AS7264
- Product name
- 2-tert-butoxycarbonylamino-3-Naphthalen-2-yl-propionic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $625
- Updated
- 2021/12/16
- Product number
- AS7264
- Product name
- 2-tert-butoxycarbonylamino-3-Naphthalen-2-yl-propionic acid
- Purity
- 95+%
- Packaging
- 5G
- Price
- $1529
- Updated
- 2021/12/16
- Product number
- CD00003378
- Product name
- 2-((tert-Butoxycarbonyl)amino)-3-(naphthalen-2-yl)propanoicacid
- Purity
- 97%
- Packaging
- 100mg
- Price
- $104
- Updated
- 2021/12/16
- Product number
- CD00003378
- Product name
- 2-((tert-Butoxycarbonyl)amino)-3-(naphthalen-2-yl)propanoicacid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $163
- Updated
- 2021/12/16
N-T-BOC-D-3-(2-NAPHTHYL)ALANINE Chemical Properties,Usage,Production
Synthesis
6960-34-5
74651-77-7
56583-58-5
1. N-Boc-L-3-(2-naphthyl)alanine (0.43 g, 2.0 mmol) was dissolved in a solvent mixture of dioxane (8 ml), water (8 ml) and triethylamine (4 ml). 2. BOC-ON (0.49 g, 2.0 mmol) was added and the reaction mixture was stirred overnight at room temperature under argon protection. 3. After completion of the reaction, water (30 ml) was added for dilution and extracted with ethyl acetate (3 x 20 ml). 4. The aqueous layer was acidified to pH=4 with 10% citric acid solution and extracted again with ethyl acetate (3 x 20 ml). 5. The organic phases were combined, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give a colorless oily product (0.52 g, 82% yield). 6. The product was characterized by 1H NMR (DMSO-d6): δ 7.8 (3H, m), 7.7 (1H, s), 7.4 (3H, m), 7.15 (1H, d), 4.2 (1H, m), 3.2 (1H, m), 2.9 (1H, m), 1.3 (9H, s).
References
[1] Patent: US5486597, 1996, A
N-T-BOC-D-3-(2-NAPHTHYL)ALANINE Preparation Products And Raw materials
Raw materials
Preparation Products
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