Boc-3-(2-Naphthyl)-D-alanine

Product Name: Boc-3-(2-Naphthyl)-D-alanine
CAS No.: 76985-10-9
Chemical Name: Boc-3-(2-Naphthyl)-D-alanine
Synonyms: BOC-2-NAL-OH;BOC-NAL(2)-OH;BOC-D-2-NAL-OH;BOC-L-2-NAL-OH;Boc-2-D-Nal-OH;BOC-D-NAL(2)-OH;BOC-ALA(2-NAPH)-OH;RARECHEM BK PT 0098;RARECHEM BK PT 0101;BOC-D-ALA(2-NAPH)-OH
CBNumber: CB5160608
Molecular Formula: C18H21NO4
Formula Weight: 315.37
MOL File: 76985-10-9.mol

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Boc-3-(2-Naphthyl)-D-alanine Property

Melting point:: 92-95 °C(lit.)
alpha: -45 º (c=1% in ethanol)
Boiling point:: 454.92°C (rough estimate)
Density: 1.2164 (rough estimate)
refractive index: 1.5740 (estimate)
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform (Sparingly), Ethanol (Sparingly), Methanol (Slightly)
form: Solid
pka: 3.88±0.30(Predicted)
color: White
optical activity: [α]20/D 45±2°, c = 1% in ethanol
BRN: 4200660
CAS DataBase Reference: 76985-10-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Safety Statements: 22-24/25
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29242990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 15478
Product name: Boc-D-2-Nal-OH
Purity: ≥97.0% (HPLC)
Packaging: 1g
Price: $105
Updated: 2023/01/07

TCI Chemical

Product number: B3616
Product name: N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $52
Updated: 2025/07/31

TCI Chemical

Product number: B3616
Product name: N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $201
Updated: 2025/07/31

TRC

Product number: B667360
Product name: Boc-3-(2-Naphthyl)-D-alanine
Packaging: 50g
Price: $555
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB47421
Product name: Boc-3-(2-naphthyl)-D-alanine
Packaging: 50g
Price: $600
Updated: 2021/12/16

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Boc-3-(2-Naphthyl)-D-alanine Chemical Properties,Usage,Production

Chemical Properties

off-white granular powder

Uses

Boc-3-(2-Naphthyl)-D-alanine is a reagent in Lanreotide trisulfide synthesis and somatostatin receptor binding activity. Reagent in the preparation by coupling and structure-activity relationships of arginine containing tripeptides as MC4 receptor ligands.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

6960-34-5

74651-77-7

56583-58-5

1. N-tert-butoxycarbonyl-L-3-(2-naphthyl)alanine (0.43 g, 2.0 mmol) was dissolved in a solvent mixture of dioxane (8 ml), water (8 ml) and triethylamine (4 ml). 2. BOC-ON (0.49 g, 2.0 mmol) was added and the reaction mixture was stirred overnight at room temperature under argon protection. 3. After completion of the reaction, water (30 ml) was added for dilution and extracted with ethyl acetate (3 x 20 ml). 4. The aqueous layer was adjusted to pH=4 with 10% citric acid solution and extracted again with ethyl acetate (3 x 20 ml). 5. The organic phases were combined, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give a colorless oily product (0.52 g, 82% yield). 6. The product was analyzed by 1H NMR. 6. The product was characterized by 1H NMR (DMSO-d6): δ 7.8 (3H, m), 7.7 (1H, s), 7.4 (3H, m), 7.15 (1H, d), 4.2 (1H, m), 3.2 (1H, m), 2.9 (1H, m), 1.3 (9H, s).

References

[1] Patent: US5486597, 1996, A

Boc-3-(2-Naphthyl)-D-alanine Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-3-(2-Naphthyl)-D-alanine Suppliers

Americas 1 Belgium 2 China 176 Europe 2 France 1 Germany 9 India 5 Japan 5 Switzerland 5 United Kingdom 11 United States 57 Global 274

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View Lastest Price from Boc-3-(2-Naphthyl)-D-alanine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-d-2-nal-oh 76985-10-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T
Release date: 2023-11-20

Career Henan Chemical Co

Product: Boc-3-(2-Naphthyl)-D-alanine 76985-10-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98-100%
Supply Ability: 1000kg
Release date: 2018-08-20

Career Henan Chemical Co

Product: Boc-3-(2-Naphthyl)-D-alanine 76985-10-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-14

76985-10-9, Boc-3-(2-Naphthyl)-D-alanineRelated Search:

D-Alanine Boc-3-(2-Naphthyl)-L-alanine EC 2.6.1.2 Phenprobamate DL-Alanine Boc-beta-alanine β-Alanine 1-(1-NAPHTHYL)-2-THIOUREA L-Alanine DI-TERT-BUTYL ETHER BOC-L-4-Chlorophe BOC-L-2-Methylphe 5-Chloro-2-iodobenzoic acid BOC-L-3-THIENYLALANINE DCHA SALT BOC-D-4-Nitrophe Boc-L-serine methyl ester BOC-D-2-CYANOPHENYLALANINE BOC-D-SER-OME

Boc-D-2-Nal-OH Boc-3-(2-Naphthyl)-D-Alanine

N-Boc-3-(2-naphthyl)-D-alanine (R)-alpha-tert-Butoxycarbonylamino-2-naphthalenepropionic Acid (R)-alpha-(Boc-amino)-2-naphthalenepropionic Acid

2-Naphthalenepropanoicacid, a-[[(1,1-diMethylethoxy)carbonyl]aMino]-,(aR)-

N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine

N-Boc-2-(2-naphthyl)-D-alanine

BOC-NAL(2)-OH

BOC-ALA(2-NAPH)-OH

BOC-ALA(2-NAPHTHYL)-OH

BOC-ALA-BETA-(2-NAPHTHYL)-OH

BOC-BETA-(2-NAPHTHYL)-D-ALANINE

BOC-BETA-(2-NAPHTHYL)-L-ALANINE

BOC-D-3-(2-NAPHTHYL)-ALANINE

BOC-D-2-NAL-OH

BOC-D-2-NAPHTHYLALANINE

BOC-D-ALA(2-NAPH)-OH

BOC-D-ALA(2-NAPHTHYL)-OH

BOC-D-ALA-BETA-(2-NAPHTHYL)-OH

BOC-L-2-NAL-OH

BOC-L-2-NAPHTHYLALANINE

BOC-L-3-(2-NAPHTHYL)-ALANINE

BOC-D-NAL(2)-OH

BOC-2-L-NAPHTHYLALANINE

BOC-2-NAL-OH

BOC-3-(2-NAPHTHYL)-ALANINE

BOC-3-(2-NAPHTHYL)-D-ALANINE

(R)-N-BOC-2-NAPHTHYLALANINE

(R)-N-BOC-2-NAPHTHYLALANINE, 95%, 98% EE

(Tert-Butoxy)Carbonyl D-2-Nal-OH

(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-naphthalen-2-ylpropanoic acid

Boc-3-(2-naphthyl)-D-alanine≥ 99% (HPLC)

(2R)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-(2-naphthalenyl)propanoate

N-Boc-3-(2-naphthyl)-D-alanine

BOC-(2-naphthyl)-D-alanine

(S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(NAPHTHALEN-2-YL)PROPANOIC ACID

(S)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID

(S)-N-BOC-2-NAPHTHYLALANINE

(R)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(NAPHTHALEN-2-YL)PROPANOIC ACID

(R)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID

RARECHEM BK PT 0098

RARECHEM BK PT 0101

N-TERT-BUTOXYCARBONYL-2-NAPHTHYL-D-ALANINE

N-TERT-BUTOXYCARBONYL-2-NAPHTHYL-L-ALANINE

N-T-BOC-D-3-(2-NAPHTHYL)-ALANINE

N-ALPHA-TERT-BUTYLOXYCARBONYL-3-(2-NAPHTHYL)-D-ALANINE

N-ALPHA-(TERT-BUTYLOXYCARBONYL)-3-(2-NAPHTHYL)-L-ALANINE

N-ALPHA-(T-BUTYLOXYCARBONYL)-3-(2-NAPHTHYL)-D-ALANINE

N-ALPHA-T-BUTOXYCARBONYL-L-3-(2-NAPHTHYL)-ALANINE

N-ALPHA-T-BUTOXYCARBONYL-3-(2-NAPHTHYL)-D-ALANINE

N-ALPHA-T-BUTOXYCARBONYL-3-(2-NAPHTHYL)-L-ALANINE

N-ALPHA-T-BOC-BETA-(2-NAPHTHYL)-D-ALANINE

N-ALPHA-T-BOC-BETA-(2-NAPHTHYL)-L-ALANINE

N-BOC-3-(2-NAPHTHYL)-L-ALANINE

(R)-N-BOC-2-Naphthylalanine, 98% ee, 95%

Boc-2-D-Nal-OH

3-Naphth-2-yl-D-alanine, N-BOC protected

N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine &gt

2-Naphthalenepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αR)-

(R)-alpha-(Boc-amino)-2-naphthalenepropionic Acid