ChemicalBook > CAS DataBase List > Boc-3-(2-Naphthyl)-D-alanine

Boc-3-(2-Naphthyl)-D-alanine

Product Name: Boc-3-(2-Naphthyl)-D-alanine
CAS No.: 76985-10-9
Chemical Name: Boc-3-(2-Naphthyl)-D-alanine
Synonyms: BOC-2-NAL-OH;BOC-NAL(2)-OH;BOC-D-2-NAL-OH;BOC-L-2-NAL-OH;Boc-2-D-Nal-OH;BOC-D-NAL(2)-OH;BOC-ALA(2-NAPH)-OH;RARECHEM BK PT 0098;RARECHEM BK PT 0101;BOC-D-ALA(2-NAPH)-OH
CBNumber: CB5160608
Molecular Formula: C18H21NO4
Formula Weight: 315.37
MOL File: 76985-10-9.mol

Less

Boc-3-(2-Naphthyl)-D-alanine Property

Melting point:: 92-95 °C(lit.)
alpha: -45 º (c=1% in ethanol)
Boiling point:: 454.92°C (rough estimate)
Density: 1.2164 (rough estimate)
refractive index: 1.5740 (estimate)
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform (Sparingly), Ethanol (Sparingly), Methanol (Slightly)
form: Solid
pka: 3.88±0.30(Predicted)
color: White
optical activity: [α]20/D 45±2°, c = 1% in ethanol
BRN: 4200660
CAS DataBase Reference: 76985-10-9(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Safety Statements: 22-24/25
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29242990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 15478
Product name: Boc-D-2-Nal-OH
Purity: ≥97.0% (HPLC)
Packaging: 1g
Price: $105
Updated: 2023/01/07

TCI Chemical

Product number: B3616
Product name: N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $52
Updated: 2025/07/31

TCI Chemical

Product number: B3616
Product name: N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $201
Updated: 2025/07/31

TRC

Product number: B667360
Product name: Boc-3-(2-Naphthyl)-D-alanine
Packaging: 50g
Price: $555
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB47421
Product name: Boc-3-(2-naphthyl)-D-alanine
Packaging: 50g
Price: $600
Updated: 2021/12/16

Less

Boc-3-(2-Naphthyl)-D-alanine Chemical Properties,Usage,Production

Chemical Properties

off-white granular powder

Uses

Boc-3-(2-Naphthyl)-D-alanine is a reagent in Lanreotide trisulfide synthesis and somatostatin receptor binding activity. Reagent in the preparation by coupling and structure-activity relationships of arginine containing tripeptides as MC4 receptor ligands.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

6960-34-5

74651-77-7

56583-58-5

1. N-tert-butoxycarbonyl-L-3-(2-naphthyl)alanine (0.43 g, 2.0 mmol) was dissolved in a solvent mixture of dioxane (8 ml), water (8 ml) and triethylamine (4 ml). 2. BOC-ON (0.49 g, 2.0 mmol) was added and the reaction mixture was stirred overnight at room temperature under argon protection. 3. After completion of the reaction, water (30 ml) was added for dilution and extracted with ethyl acetate (3 x 20 ml). 4. The aqueous layer was adjusted to pH=4 with 10% citric acid solution and extracted again with ethyl acetate (3 x 20 ml). 5. The organic phases were combined, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give a colorless oily product (0.52 g, 82% yield). 6. The product was analyzed by 1H NMR. 6. The product was characterized by 1H NMR (DMSO-d6): δ 7.8 (3H, m), 7.7 (1H, s), 7.4 (3H, m), 7.15 (1H, d), 4.2 (1H, m), 3.2 (1H, m), 2.9 (1H, m), 1.3 (9H, s).

References

[1] Patent: US5486597, 1996, A

Boc-3-(2-Naphthyl)-D-alanine Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Boc-3-(2-Naphthyl)-D-alanine Suppliers

Americas 1 Belgium 2 China 175 Europe 2 France 1 Germany 9 India 5 Japan 5 Switzerland 5 United Kingdom 11 United States 57 Global 273

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Shanghai HC Biotech Co., Ltd

Tel: 021-20227858
Fax: +86-21-20227857
Email: sale@hcbiotech.com.cn
Country: China
ProdList: 1095
Advantage: 55

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Suzhou haiyu Biochem Industrial Co., LTD

Tel: 512-68097639 18013585858
Fax: 0512-
Email: 744942877@qq.com
Country: China
ProdList: 915
Advantage: 62

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

RYSS TECH LTD

Tel: 400-188-0725 +86 21 34310725 13611771617
Fax: +86 21 34311076
Country: China
ProdList: 2002
Advantage: 57

Shenzhen Sungening Bio-Tech Co., Ltd

Tel: +86-0755-89668383
Fax: +86-0755-89594066/4038
Email: sales@sungening.com
Country: China
ProdList: 1319
Advantage: 65

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Hygeia (Chengdu) pharmaceutical technique Co., Ltd

Tel: 028-84502008 13568869383
Fax: 028-66476329
Email: sales@hygeiapharm.com
Country: China
ProdList: 296
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Shanghai CanSpecsci Instrument Co., Ltd.

Tel: 400-6087598 15021221957
Fax: 4006087598-8012
Email: order@canspecsci.com
Country: China
ProdList: 2001
Advantage: 56

NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4613
Advantage: 58

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

LABTER PHARMATECH(BEIJING) CO.,LTD

Tel: 010-56330744 18310155299
Fax: 010-56330744
Email: sales@labter.com.cn
Country: China
ProdList: 20000
Advantage: 55

Nanjing Derno Pharmaceutical Technology Co., Ltd.

Tel: 025-86957866 13952093866
Fax: 025-68661287
Email: sales@dernopharm.com
Country: China
ProdList: 932
Advantage: 58

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9484
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai GL Peptide Ltd.

Tel: +86-21-61263340; 17609490614 13764994101
Fax: 021-61263399
Email: fisherwang@glschina.com
Country: China
ProdList: 8258
Advantage: 55

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9941
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Wuxi Asia Peptide Biotechnology Limited Company

Tel: 0510-83583050 13771062561
Fax: 0510-83583039
Email: willsun@peptide-search.com
Country: China
ProdList: 6716
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Sichuan Lancent Medical Devices Co., Ltd.

Tel: 18111675298
Fax: -
Email: stochem@aliyun.com
Country: China
ProdList: 212
Advantage: 58

Sichuan jiayinglai technology CO.,LTD

Tel: 028-028-88457210 18190964009
Fax: QQ3213375147
Email: 3054240163@qq.com
Country: China
ProdList: 2293
Advantage: 55

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Less

View Lastest Price from Boc-3-(2-Naphthyl)-D-alanine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-d-2-nal-oh 76985-10-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T
Release date: 2023-11-20

Career Henan Chemical Co

Product: Boc-3-(2-Naphthyl)-D-alanine 76985-10-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98-100%
Supply Ability: 1000kg
Release date: 2018-08-20

Career Henan Chemical Co

Product: Boc-3-(2-Naphthyl)-D-alanine 76985-10-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-14

76985-10-9, Boc-3-(2-Naphthyl)-D-alanineRelated Search:

D-Alanine Boc-3-(2-Naphthyl)-L-alanine EC 2.6.1.2 Phenprobamate DL-Alanine Boc-beta-alanine β-Alanine 1-(1-NAPHTHYL)-2-THIOUREA L-Alanine DI-TERT-BUTYL ETHER BOC-L-4-Chlorophe BOC-L-2-Methylphe 5-Chloro-2-iodobenzoic acid BOC-L-3-THIENYLALANINE DCHA SALT BOC-D-4-Nitrophe Boc-L-serine methyl ester BOC-D-2-CYANOPHENYLALANINE BOC-D-SER-OME

Boc-D-2-Nal-OH Boc-3-(2-Naphthyl)-D-Alanine

N-Boc-3-(2-naphthyl)-D-alanine (R)-alpha-tert-Butoxycarbonylamino-2-naphthalenepropionic Acid (R)-alpha-(Boc-amino)-2-naphthalenepropionic Acid

2-Naphthalenepropanoicacid, a-[[(1,1-diMethylethoxy)carbonyl]aMino]-,(aR)-

N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine

N-Boc-2-(2-naphthyl)-D-alanine

BOC-NAL(2)-OH

BOC-ALA(2-NAPH)-OH

BOC-ALA(2-NAPHTHYL)-OH

BOC-ALA-BETA-(2-NAPHTHYL)-OH

BOC-BETA-(2-NAPHTHYL)-D-ALANINE

BOC-BETA-(2-NAPHTHYL)-L-ALANINE

BOC-D-3-(2-NAPHTHYL)-ALANINE

BOC-D-2-NAL-OH

BOC-D-2-NAPHTHYLALANINE

BOC-D-ALA(2-NAPH)-OH

BOC-D-ALA(2-NAPHTHYL)-OH

BOC-D-ALA-BETA-(2-NAPHTHYL)-OH

BOC-L-2-NAL-OH

BOC-L-2-NAPHTHYLALANINE

BOC-L-3-(2-NAPHTHYL)-ALANINE

BOC-D-NAL(2)-OH

BOC-2-L-NAPHTHYLALANINE

BOC-2-NAL-OH

BOC-3-(2-NAPHTHYL)-ALANINE

BOC-3-(2-NAPHTHYL)-D-ALANINE

(R)-N-BOC-2-NAPHTHYLALANINE

(R)-N-BOC-2-NAPHTHYLALANINE, 95%, 98% EE

(Tert-Butoxy)Carbonyl D-2-Nal-OH

(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-naphthalen-2-ylpropanoic acid

Boc-3-(2-naphthyl)-D-alanine≥ 99% (HPLC)

(2R)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-(2-naphthalenyl)propanoate

N-Boc-3-(2-naphthyl)-D-alanine

BOC-(2-naphthyl)-D-alanine

(S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(NAPHTHALEN-2-YL)PROPANOIC ACID

(S)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID

(S)-N-BOC-2-NAPHTHYLALANINE

(R)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(NAPHTHALEN-2-YL)PROPANOIC ACID

(R)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID

RARECHEM BK PT 0098

RARECHEM BK PT 0101

N-TERT-BUTOXYCARBONYL-2-NAPHTHYL-D-ALANINE

N-TERT-BUTOXYCARBONYL-2-NAPHTHYL-L-ALANINE

N-T-BOC-D-3-(2-NAPHTHYL)-ALANINE

N-ALPHA-TERT-BUTYLOXYCARBONYL-3-(2-NAPHTHYL)-D-ALANINE

N-ALPHA-(TERT-BUTYLOXYCARBONYL)-3-(2-NAPHTHYL)-L-ALANINE

N-ALPHA-(T-BUTYLOXYCARBONYL)-3-(2-NAPHTHYL)-D-ALANINE

N-ALPHA-T-BUTOXYCARBONYL-L-3-(2-NAPHTHYL)-ALANINE

N-ALPHA-T-BUTOXYCARBONYL-3-(2-NAPHTHYL)-D-ALANINE

N-ALPHA-T-BUTOXYCARBONYL-3-(2-NAPHTHYL)-L-ALANINE

N-ALPHA-T-BOC-BETA-(2-NAPHTHYL)-D-ALANINE

N-ALPHA-T-BOC-BETA-(2-NAPHTHYL)-L-ALANINE

N-BOC-3-(2-NAPHTHYL)-L-ALANINE

(R)-N-BOC-2-Naphthylalanine, 98% ee, 95%

Boc-2-D-Nal-OH

3-Naphth-2-yl-D-alanine, N-BOC protected

N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine &gt

2-Naphthalenepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αR)-

(R)-alpha-(Boc-amino)-2-naphthalenepropionic Acid