BOC-D-SER-OME

Product Name: BOC-D-SER-OME
CAS No.: 95715-85-8
Chemical Name: BOC-D-SER-OME
Synonyms: BOC-D-SERINE METHYL ESTER;BOC-D-SER-OME;)-D-serine methyL;Boc-D-Ser-OMe(Oil);N-BOC-D-ser-methylester;N-D-serine methyl ester;N-BOC-D-serine methylester;N-FmocD-serine methylester;Nicotinic Acid Impurity 34;N-BOC-D-Serine methyleester
CBNumber: CB6309491
Molecular Formula: C9H17NO5
Formula Weight: 219.24
MOL File: 95715-85-8.mol

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BOC-D-SER-OME Property

Boiling point:: 215 °C(lit.)
Density: 1.08 g/mL at 25 °C(lit.)
refractive index: n20/D 1.453(lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform, Methanol
form: Liquid
pka: 10.70±0.46(Predicted)
color: Colorless to yellow
optical activity: [α]25/D +18.8°, c = 5 in methanol
InChI: InChI=1S/C9H17NO5/c1-9(2,3)15-8(13)10-6(5-11)7(12)14-4/h6,11H,5H2,1-4H3,(H,10,13)/t6-/m1/s1
InChIKey: SANNKFASHWONFD-ZCFIWIBFSA-N
SMILES: C(OC)(=O)[C@@H](CO)NC(OC(C)(C)C)=O
CAS DataBase Reference: 95715-85-8(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
WGK Germany: 3
HS Code: 29241990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 446068
Product name: N-(tert-Butoxycarbonyl)-D-serine methyl ester
Purity: 97%
Packaging: 10g
Price: $212.05
Updated: 2025/07/31

TCI Chemical

Product number: B4859
Product name: N-(tert-Butoxycarbonyl)-D-serine Methyl Ester
Purity: >98.0%(HPLC)(N)
Packaging: 1g
Price: $25
Updated: 2025/07/31

TCI Chemical

Product number: B4859
Product name: N-(tert-Butoxycarbonyl)-D-serine Methyl Ester
Purity: >98.0%(HPLC)(N)
Packaging: 5g
Price: $88
Updated: 2025/07/31

Usbiological

Product number: 005161
Product name: N-tert-Butoxycarbonyl-D-Serine Methyl Ester
Packaging: 1g
Price: $312
Updated: 2021/12/16

Usbiological

Product number: 263371
Product name: N-tert-Butoxycarbonyl D-serine methyl ester
Packaging: 5g
Price: $319
Updated: 2021/12/16

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BOC-D-SER-OME Chemical Properties,Usage,Production

Chemical Properties

colorless to light yellow liquid

Uses

Protected D-Serine.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

24424-99-5

2104-89-4

95715-85-8

[Step 1] Synthesis of methyl (R)-2-((tert-butoxycarbonyl)amino)-3-hydroxypropionate: To a solution of methanol (50 mL) containing methyl (R)-2-amino-3-hydroxypropionate (3.0 g, 19 mmol) and triethylamine (8.1 mL, 58 mmol) was slowly added di-tert-butyl dicarbonate (4.6 g, 21 mmol). The reaction mixture was stirred at room temperature for 14 h. The reaction was terminated by the addition of dilute hydrochloric acid. After continued stirring for 1 h, the reaction mixture was diluted with the addition of water and subsequently extracted with ethyl acetate. The organic layers were combined, washed sequentially with saturated aqueous sodium bicarbonate and pure water, dried over anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography (eluent ratio: hexane/ethyl acetate=20:1→2:1) to afford 4.1 g (97% yield) of the title compound ((R)-2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoic acid methyl ester, hereinafter referred to as Reference Example compound 35).

References

[1] Patent: EP2832724, 2015, A1. Location in patent: Paragraph 0186
[2] Tetrahedron Letters, 1995, vol. 36, # 39, p. 7031 - 7034
[3] Patent: WO2013/110643, 2013, A1. Location in patent: Paragraph 00104; 00105
[4] Tetrahedron, 1996, vol. 52, # 36, p. 11673 - 11694
[5] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 3, p. 923 - 928

BOC-D-SER-OME Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-D-SER-OME Suppliers

Americas 1 Canada 1 China 224 Europe 2 Germany 2 India 21 Japan 2 Switzerland 3 United Kingdom 3 United States 25 Global 284

Shanghai Chiral Chemicals Inc.

Tel: 021-37285021 13472570865
Fax: 86-021-51714507
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Advantage: 64

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
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Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
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Sichuan Tongsheng Amino acids Co.,Ltd.

Tel: 0838-2274206 13908101207
Fax: +86-838-2274207
Email: sales@biots.cn
Country: China
ProdList: 256
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
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ProdList: 24529
Advantage: 81

Energy Chemical

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GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
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Email: ymbetter@glbiochem.com
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Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
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ProdList: 18207
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Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
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View Lastest Price from BOC-D-SER-OME manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Boc-D-Ser-OMe 95715-85-8
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1000kgs
Release date: 2021-10-28

Sichuan Jiaying Lai Technology Co.,LTD

Product: Boc-D-Ser-OMe 95715-85-8
Price: US $1.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100KG
Release date: 2019-07-21

Career Henan Chemical Co

Product: BOC-D-SER-OME 95715-85-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-16

95715-85-8, BOC-D-SER-OMERelated Search:

Boc-L-Ser-OMe (oil) BOC-L-4-Chlorophe BOC-L-2-Methylphe 5-Chloro-2-iodobenzoic acid BOC-L-3-THIENYLALANINE DCHA SALT BOC-D-4-Nitrophe Boc-3-(2-Naphthyl)-D-alanine BOC-D-2-CYANOPHENYLALANINE BOC-D-3,4-Dichlorophe N-tert-Butoxycarbonyl-4-cyanophenyl-D-alanine BOC-D-4-Trifluoromethylphe BOC-L-2-Trifluoromethylphe BOC-D-PENTAFLUOROPHENYLALANINE BOC-L-2-NITROPHENYLALANINE Boc-4-Bromo-D-beta-phenylalanine BOC-L-2-CYANOPHENYLALANINE BOC-D-SER-OME Boc-D-Serine

N-(TERT-BUTOXYCARBONYL)-D-SERINE METHYL ESTER

BOC-D-SERINE METHYL ESTER

BOC-D-SER-OME

D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester (9CI)

N-(TERT-BBUTOXYCARBONYL)-L-SERINE METHYL ESTER

BOC-D-SERINE METHYLESTER OIL

N-BOC-D-serine methylester

N-BOC-D-ser-methylester

(R)-methyl 2-(tert-butoxycarbonylamino)-3-hydroxypropanoate

N-Butoxycarbonyl-D-Serine Methyl Ester

Methyl (2r)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

methyl (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-hydroxypropanoate

N-[(1,1-DiMethylethoxy)carbonyl]-D-serine Methyl Ester

tert-Butyl [(R)-1-(Methoxycarbonyl)-2-hydroxyethyl]carbaMate

Boc-D-Ser-OMe(Oil)

(R)-Methyl 2-((tert-butoxycarbonyl)aMino)-3-hydroxypropanoate/Boc-D-Ser-OMe

N-(tert-Butoxycarbonyl)-D-serine methyl ester 97%

methyl(tert-butoxycarbonyl)-D-serinate

(R)-Boc-2-amino-3-hydroxypropionic acid methyl ester hydrochloride

Boc-D-serine methyl ester≥ 98% (HPLC)

Boc-D-β-hydroxyalanine methyl ester

N-Boc-D-serine Methyl Ester,99%e.e.

N-BOC-D-Serine methyleester

(Tert-Butoxy)Carbonyl D-Ser-OMe (Syrup)

N-D-serine methyl ester

(-)-METHYL N-BOC-D-SERINATE

D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

)-D-serine methyL

TIANFUCHEM--95715-85-8--High purity BOC-D-SER-OME factory price

N-FmocD-serine methylester

Nicotinic Acid Impurity 34

<i>N</i>-(<i>tert</i>-Butoxycarbonyl)-<sc>D</sc>-serine methyl ester

N-Boc-D-serine methyl ester, 97%

95715-85-8

Amino Acid Derivatives

Serine

Peptide Synthesis

Specialty Synthesis

Pyridines

Chiral Reagents

Intermediates

Serine [Ser, S]

Amino Acids & Derivatives

Amino Acid Derivatives

Peptide Synthesis

Serine

Heterocyclic Compounds

N-BOC