Description Supplements Mechanism of Action Shipping & Storage Condition
ChemicalBook > CAS DataBase List > 5-Methyltetrahydrofolic acid

5-Methyltetrahydrofolic acid

Description Supplements Mechanism of Action Shipping & Storage Condition
Product Name
5-Methyltetrahydrofolic acid
CAS No.
134-35-0
Chemical Name
5-Methyltetrahydrofolic acid
Synonyms
MethylFolate;5-methyltetrahydrofolate;methyl-THF;5-METHYL-THF;5-Methyl-5,6,7,8-tetrahydrofolic acid;5-Methyltetrahydrofolic Acid CalciuM Salt Trihydrate;Prefolic A;methyl-H4F;n5-CH3-THF;methyl acid
CBNumber
CB5500949
Molecular Formula
C20H25N7O6
Formula Weight
459.46
MOL File
134-35-0.mol
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5-Methyltetrahydrofolic acid Property

Melting point:
>300°C (dec.)
Density 
1.62±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Aqueous Base (Slightly, Sonicated)
form 
Solid
pka
3.51±0.10(Predicted)
color 
Pale Beige
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16159
Product name
5-Methyltetrahydrofolic Acid
Purity
≥98%
Packaging
5mg
Price
$158
Updated
2021/12/16
Cayman Chemical
Product number
16159
Product name
5-Methyltetrahydrofolic Acid
Purity
≥98%
Packaging
1mg
Price
$35
Updated
2021/12/16
Cayman Chemical
Product number
16159
Product name
5-Methyltetrahydrofolic Acid
Purity
≥98%
Packaging
10mg
Price
$263
Updated
2021/12/16
Usbiological
Product number
017430
Product name
5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate
Packaging
10mg
Price
$446
Updated
2021/12/16
TRC
Product number
M338145
Product name
N-MethyltetrahydrofolicAcid
Packaging
1g
Price
$85
Updated
2021/12/16
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5-Methyltetrahydrofolic acid Chemical Properties,Usage,Production

Description

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.

Supplements

5-Methyltetrahydrofolic acid is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.

Mechanism of Action

Prefolic A, also known as 5-Methyltetrahydrofolate, is a biologically active form of folic acid that functions, in conjunction with vitamin B12, as a methyl-group donor involved in the conversion of homocysteine to methionine. Methyl folate is an active metabolite of folic acid. Vitamin supplement in health care products.

Shipping & Storage Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Stored in dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Shelf Life can be more than 2 years if stored properly.

Chemical Properties

Off-White Solid

Uses

5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.

Uses

5-Methyltetrahydrofolic acid is a metabolite of Folic acid; inhibits photosensitization reactions and strand breaks in DNA. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.

General Description

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group.
5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.

5-Methyltetrahydrofolic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Methyltetrahydrofolic acid Suppliers

Canada 2 China 122 France 1 Germany 1 India 10 Switzerland 1 United States 10 USA 1 Global 148
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
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United States
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2123
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70
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
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United States
ProdList
6391
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58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
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58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
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58
CarboMer, Inc.
Tel
--
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Email
sales@carbomer.com
Country
United States
ProdList
4026
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HONEST JOY HOLDINGS LIMITED
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Email
sales@honestjoy.cn
Country
United States
ProdList
6675
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54
MedChemExpress
Tel
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Fax
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Email
sales@medchemexpress.com
Country
United States
ProdList
6398
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58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
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69
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
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81
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View Lastest Price from 5-Methyltetrahydrofolic acid manufacturers

airuikechemical co., ltd.
Product
methyl folate 134-35-0
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08
Hebei Kingfiner Technology Development Co.Ltd
Product
5-Methyltetrahydrofolic acid 134-35-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2024-06-17
Hebei Weibang Biotechnology Co., Ltd
Product
5-Methyltetrahydrofolic acid 134-35-0
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2021-09-28

134-35-0, 5-Methyltetrahydrofolic acidRelated Search:

Folic acid Lipoic acid L-Tetrahydrofolic Acid 2-Methyltetrahydrofuran Whey protein concentrate 2-Methylnaphthalene Hydrogen Imidazolidine ANTIOXIDANT 765 (2S)-2-[[4-[Bis[(2-aMino-4-oxo-1,4-dihydropteridin-6-yl)Methyl]aMino]benzoyl]aMino]pentanedioic Acid Folic Acid Impurity C N-(p-Aminobenzoyl)glutamic acid 6-hydroxymethylpterin Levomefolate calcium 2-Amino-7-(chloromethyl)pteridin-4(1H)-one Folitixorin (Mixture of DiastereoMers) 2-Amino-4-hydroxy-1H-pteridine N-(4-aminobenzoyl)- D-Glutamic acid

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  • 5-Methyl-5,6,7,8-tetrahydrofolic acid
  • 5-Methyltetrahydropteroyl monoglutamate
  • 5-Methyltetrahydropteroylglutamic acid
  • N5-Methyltetrahydropteroylglutamate
  • N-Methyltetrahydrofolate
  • N-Methyltetrahydrofolic acid
  • Prefolic A
  • L-Methyl Folate
  • (2S)-2-(4-(((2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
  • 5-Methyltetrahydrofolate (mixture of diastereomers)
  • 5-methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
  • 5-METHYL-THF
  • methyl-H4F
  • methyl-THF
  • n5-methyltetrahydrofolate
  • N5-methyltetrahydropteroyl mono-L-glutamate
  • N5-methyl-THF
  • 5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate (Mixture of Diastereomers)
  • 5-Methyltetrahydrofolic Acid CalciuM Salt Trihydrate
  • 5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate (Also See: L375720)
  • N-[4-[[(2-AMino-3,4,5,6,7,8-hexahydro-5-Methyl-4-oxo-6-pteridinyl)Methyl]aMino]benzoyl]-L-glutaMic Acid CalciuM Trihydrate
  • N5-Methyl tetrahydrofolic acid
  • METHYL FOLATE(METAFOLIN)(P)
  • MethylFolate
  • 2-[4-[(2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid
  • n5-CH3-THF
  • 5-methyltetrahydrofolate
  • METHYLTETRAHYDROFOLICACID
  • 5-methyl-5,6,7,8-tetrahydrofolate
  • N-[4-[[(2-Amino-1,4-dihydro-4-oxopteridin)-6-ylmethyl]amino]benzoyl]-L-glutamic acid 5-methyl ester
  • L-Glutamic acid, N-[4-[[(2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
  • Folic Acid Impurity 36
  • 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) 99 atom % 13C, 95% (CP)
  • 5-Methyltetrahydrofolic acid-(glutamic acid-13C5)
  • 5-methyltetrahydrofolicaci
  • 5-Methyltetrahydrofolic acid 1mg/ml in water
  • 5-METHYLTETRAHYDROFOLIC ACID
  • L-methylfolate Methyl Folate
  • 5-Methylterahydrofolic acid
  • 5-Methyltetrahydrofolic acid in DMSO:H2O=1:1
  • 134-35-0
  • C20H29CaN7O9
  • C20H20N7O6
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