ChemicalBook > CAS DataBase List > 5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide

5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide

Product Name
5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide
CAS No.
99519-84-3
Chemical Name
5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide
Synonyms
L-651582;NSC 609974;MERCK L651582;carboxyamido-triazole;5-amino-1-[4-(4-chlorobenzoyl)-3,5-dichlorobenzyl]-1,2,3-triazole-4-carboxamide;5-Amino-1-[4-(4-chlorobenzoyl)-3,5-dichlorobenzyl]-1H-1,2,3-triazole-4-carboxamide;1-[3,5-Dichloro-4-(4-chlorobenzoyl)benzyl]-5-amino-1H-1,2,3-triazole-4-carboxamide;5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide;1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE-5-AMINO-1-[[3,5-DICHLORO-4-(4-CHLOROBENZOYL)PHENYL]METHYL];5-AMINO-1-[[3,5-DICHLORO-4-(4-CHLORO-BENZOYL)-PHENYL]METHYL]-1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE
CBNumber
CB5501698
Molecular Formula
C17H12Cl3N5O2
Formula Weight
424.67
MOL File
99519-84-3.mol
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5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide Property

Melting point:
200-202 °C
Boiling point:
685.5±65.0 °C(Predicted)
Density 
1.65±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
DMSO: soluble10mg/mL (clear solution)
form 
powder
pka
14.16±0.50(Predicted)
color 
white to beige
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0408
Product name
Carboxyamidotriazole
Purity
≥98% (HPLC)
Packaging
5mg
Price
$117
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0408
Product name
Carboxyamidotriazole
Purity
≥98% (HPLC)
Packaging
25mg
Price
$367
Updated
2024/03/01
Cayman Chemical
Product number
28732
Product name
Carboxyamidotriazole
Packaging
5mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
28732
Product name
Carboxyamidotriazole
Packaging
25mg
Price
$414
Updated
2024/03/01
Cayman Chemical
Product number
28732
Product name
Carboxyamidotriazole
Packaging
10mg
Price
$187
Updated
2024/03/01
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5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide Chemical Properties,Usage,Production

Uses

Carboxyamidotriazole is an orally active calcium channel blocker. Carboxyamidotriazole also exhibits inhibition of pro-inflammatory cytokines in tumor associated macrophages as potential anti-cancer m echanism.

Biological Activity

Orally active Ca 2+ channel blocker; inhibits K + - and carbachol-stimulated Ca 2+ influx (IC 50 values are 500 and 935 nM respectively). Exhibits antiproliferative, antiangiogenic and antimetastatic activity in vivo and displays selectivity towards numerous mismatch repair-deficient tumor cell lines in vitro .

storage

Store at +4°C

5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide Suppliers

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View Lastest Price from 5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide manufacturers

Henan Fengda Chemical Co., Ltd
Product
5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide 99519-84-3
Price
US $8.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Henan Fengda Chemical Co., Ltd
Product
5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide 99519-84-3
Price
US $8.00-1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08

99519-84-3, 5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamideRelated Search:

Benzoyl peroxide Chlorantraniliprole Benzyl chloride Benzyl acetate Sodium carboxymethyl cellulose 1H-Benzotriazole N,N-Dimethylformamide Benzyl alcohol 1,2,4-Triazole Formamide Benzyl benzoate Benzyl 4-ISOCYANATO-1-(TRIFLUOROACETYL)PIPERIDINE 2-Chloro-4-methylbenzaldehyde 2',6'-Dichloroacetophenone 3-Chloro-4-methylbenzylamine 2,4'-Dichlorobenzophenone 4-METHYL-1-PHENYLMETHYL-1H-1,2,3-TRIAZOLE

  • 5-Amino-1-[3,5-dichloro-4-(4-chlorobenzoyl)benzyl]-1H-[1,2,3]triazole-4-carboxylic acid amide
  • 1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE-5-AMINO-1-[[3,5-DICHLORO-4-(4-CHLOROBENZOYL)PHENYL]METHYL]
  • carboxyamido-triazole
  • 5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide
  • 1-[3,5-Dichloro-4-(4-chlorobenzoyl)benzyl]-5-amino-1H-1,2,3-triazole-4-carboxamide
  • 5-Amino-1-[4-(4-chlorobenzoyl)-3,5-dichlorobenzyl]-1H-1,2,3-triazole-4-carboxamide
  • L-651582
  • carboxyaMido-triazole(5-AMino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxaMide)
  • Merck L651582 5-aMino-1-[3,5-dichloro-4-(4-chloro-benzoyl)-benzyl]-1H-[1,2,3]triazole-4-carboxylic acid aMide
  • MERCK L651582
  • NSC 609974
  • 5-amino-1-[4-(4-chlorobenzoyl)-3,5-dichlorobenzyl]-1,2,3-triazole-4-carboxamide
  • 5-AMINO-1-[[3,5-DICHLORO-4-(4-CHLORO-BENZOYL)-PHENYL]METHYL]-1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE
  • 99519-84-3
  • C17H12Cl3N5O2