ChemicalBook > CAS DataBase List > 4,4'-Bis(methoxycarbonly)-2,2'-bipyridine

4,4'-Bis(methoxycarbonly)-2,2'-bipyridine

Product Name
4,4'-Bis(methoxycarbonly)-2,2'-bipyridine
CAS No.
71071-46-0
Chemical Name
4,4'-Bis(methoxycarbonly)-2,2'-bipyridine
Synonyms
Nsc297840;4-Bis(methoxycarbonly)-2;4,4′-Dimethoxycarbonyl-2,2′-bipyridine;4,4'-bis(carbomethoxy)-2,2'-bipyridine;4,4'-bis(methoxycarbonly)-2,2'-bipyridine;4,4'-BIS(METHOXYCARBONYL)-2,2'-BIPYRIDINE;Dimethyl 2,2'-Bipyridine-4,4'-dicarboxylate;Dimethyl 2,2'-Bipyridine-4,4'-dicarboxylate >2,2'-Bipyridine-4,4'-dicarboxylic acid dimethyl ester;2,2'-Bipyridine-4,4'-biscarboxylic acid dimethyl ester
CBNumber
CB5511651
Molecular Formula
C14H12N2O4
Formula Weight
272.26
MOL File
71071-46-0.mol
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4,4'-Bis(methoxycarbonly)-2,2'-bipyridine Property

Melting point:
208.0 to 212.0 °C
Boiling point:
440.8±45.0 °C(Predicted)
Density 
1.254±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
1.85±0.30(Predicted)
color 
White to Almost white
InChI
InChI=1S/C14H12N2O4/c1-19-13(17)9-3-5-15-11(7-9)12-8-10(4-6-16-12)14(18)20-2/h3-8H,1-2H3
InChIKey
HBWBVIDKBKOVEX-UHFFFAOYSA-N
SMILES
C1(C2=NC=CC(C(OC)=O)=C2)=NC=CC(C(OC)=O)=C1
CAS DataBase Reference
71071-46-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-39
WGK Germany 
3
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
742481
Product name
Dimethyl 2,2′-bipyridine-4,4′-dicarboxylate
Purity
≥98.0% (HPLC)
Packaging
100mg
Price
$105
Updated
2025/07/31
Sigma-Aldrich
Product number
742481
Product name
Dimethyl 2,2′-bipyridine-4,4′-dicarboxylate
Purity
≥98.0% (HPLC)
Packaging
500mg
Price
$436
Updated
2023/06/20
TCI Chemical
Product number
D4635
Product name
Dimethyl 2,2'-Bipyridine-4,4'-dicarboxylate
Purity
>98.0%(T)
Packaging
1g
Price
$101
Updated
2025/07/31
TCI Chemical
Product number
D4635
Product name
Dimethyl 2,2'-Bipyridine-4,4'-dicarboxylate
Purity
>98.0%(T)
Packaging
5g
Price
$335
Updated
2025/07/31
TRC
Product number
D472748
Product name
Dimethyl 2,2'-Bipyridine-4,4'-dicarboxylate
Packaging
250mg
Price
$75
Updated
2021/12/16
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4,4'-Bis(methoxycarbonly)-2,2'-bipyridine Chemical Properties,Usage,Production

Uses

4,4'-Bis(methoxycarbonyl)-2,2'-bipyridine is a chemical reaction reagent or organic synthesis intermediate that can be used as a ligand in cross-coupling reactions, binding to metal ions and forming complexes. 4,4'-Bis(methoxycarbonyl)-2,2'-bipyridine has a constant value that maximizes the yield of the reaction and has luminescence, which can be used for voltammetry studies. The transfer of the chromophore or the catalyst can be optimized using this product. 4,4'-Bis(methoxycarbonyl)-2,2'-bipyridine provides a method for cross-coupling reactions using electrochemical studies and dichroism.

Synthesis

67-56-1

6813-38-3

71071-46-0

General procedure for the synthesis of methyl 2,2'-bipyridine-4,4'-dicarboxylate from methanol and 2,2'-bipyridine-4,4'-dicarboxylic acid: 2,2'-Bipyridine-4,4'-dicarboxylic acid (2.00 g, 8.10 mmol) was suspended in methanol (150 mL), and thionyl chloride (1492 μL, 20.48 mmol) was slowly added dropwise. The reaction mixture was stirred under reflux conditions overnight. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was partitioned between dichloromethane (100 mL) and water (100 mL). The organic phase was washed three times with saturated aqueous sodium bicarbonate and dried over anhydrous sodium sulfate. Finally, the solvent was removed by reduced pressure distillation to give the white solid product methyl 2,2'-bipyridine-4,4'-dicarboxylate (2.00 g, 90% yield).

References

[1] Journal of the American Chemical Society, 2007, vol. 129, # 18, p. 5919 - 5925
[2] Tetrahedron Asymmetry, 2013, vol. 24, # 8, p. 515 - 525
[3] Inorganic Chemistry, 2018, vol. 57, # 15, p. 9316 - 9326
[4] Dalton Transactions, 2018, vol. 47, # 37, p. 13081 - 13087
[5] Journal of the American Chemical Society, 2016, vol. 138, # 51, p. 16815 - 16826

4,4'-Bis(methoxycarbonly)-2,2'-bipyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4'-Bis(methoxycarbonly)-2,2'-bipyridine Suppliers

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View Lastest Price from 4,4'-Bis(methoxycarbonly)-2,2'-bipyridine manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.
Product
4,4'-Bis(methoxycarbonly)-2,2'-bipyridine 71071-46-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
2000KGS
Release date
2025-10-24
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
4,4'-Bis(methoxycarbonly)-2,2'-bipyridine 71071-46-0
Price
US $1.10-9.90/kg
Min. Order
100kg
Purity
99%min
Supply Ability
100kg
Release date
2025-08-14
Shanghai UCHEM Inc.
Product
Dimethyl 2,2'-bipyridine-4,4'-dicarboxylate 71071-46-0
Price
US $17.00-81.00/g
Min. Order
5g
Purity
0.98
Supply Ability
25kg
Release date
2024-07-09

71071-46-0, 4,4'-Bis(methoxycarbonly)-2,2'-bipyridineRelated Search:

Methyl anthranilate 2,2'-Bipyridine Dimethyl phthalate Dimethyl ether Methyl benzoate Dimethyl sebacate ETHANE Methyl formate Dimethyl fumarate 4,4'-Bipyridine DIPIPERIDINOMETHANE Dimethyl sulfoxide N,N-Dimethylformamide Methylparaben Dimethyl carbonate AcidEster DIBUTYL 2,2'-BIPYRIDINE-4,4'-DICARBOXYLATE Methyl chloroformate

  • 4,4'-bis(methoxycarbonly)-2,2'-bipyridine
  • 2,2'-Bipyridinyl-4,4'-dicarboxylic acid dimethyl ester
  • 2,2'-Bipyridine-4,4'-bis(carboxylic acid methyl) ester
  • 2,2'-Bipyridine-4,4'-biscarboxylic acid dimethyl ester
  • 2,2'-Bipyridine-4,4'-dicarboxylic acid dimethyl ester
  • 2,2'-Bipyridine-4,4'-diylbis(formic acid methyl) ester
  • Nsc297840
  • [2,2′-Bipyridine]-4,4′-dicarboxylic acid 4,4′-dimethyl ester
  • 4,4′-Dimethoxycarbonyl-2,2′-bipyridine
  • Dimethyl [2,2'-bipyridine]-4,4'-dicarboxylate≥ 98% (HPLC)
  • 4,4'-bis(carbomethoxy)-2,2'-bipyridine
  • 2-(4-methoxycarbonyl-2-pyridinyl)-4-pyridinecarboxylic acid methyl ester
  • Dimethyl 2,2'-Bipyridine-4,4'-dicarboxylate &gt
  • 4,4'-Bis(methoxycarbonly)-2,2'-bipyridine ISO 9001：2015 REACH
  • 4-Bis(methoxycarbonly)-2
  • Dimethyl 2,2'-Bipyridine-4,4'-dicarboxylate
  • 4,4'-BIS(METHOXYCARBONYL)-2,2'-BIPYRIDINE
  • (2,2')BIPYRIDINYL-4,4'-DICARBOXYLIC ACID DIMETHYL ESTER
  • Dimethyl [2,2′-bipyridine]-4,4′-dicarboxylate, CAS 71071-46-0
  • 71071-46-0