MEF2A antibody
Source Reactivity Background References- Product Name
- MEF2A antibody
- Chemical Name
- MEF2A antibody
- Synonyms
- MEF2A antibody;Mouse Monoclonal MEF2A Antibody
- CBNumber
- CB55653712
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb106475
- Product name
- MEF2A antibody
- Purity
- Immunogen affinity purified
- Packaging
- 20μl(Trial size)
- Price
- $256.7
- Updated
- 2021/12/16
- Product number
- orb106476
- Product name
- MEF2A antibody
- Purity
- Immunogen affinity purified
- Packaging
- 20μl(Trial size)
- Price
- $256.7
- Updated
- 2021/12/16
- Product number
- orb106476
- Product name
- MEF2A antibody
- Purity
- Immunogen affinity purified
- Packaging
- 50μl
- Price
- $357
- Updated
- 2021/12/16
- Product number
- orb106475
- Product name
- MEF2A antibody
- Purity
- Immunogen affinity purified
- Packaging
- 50μl
- Price
- $357
- Updated
- 2021/12/16
- Product number
- orb153530
- Product name
- MEF2A antibody
- Purity
- Affinity purified
- Packaging
- 100μL
- Price
- $370.6
- Updated
- 2021/12/16
MEF2A antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human
Background
MEF2A is a member of the MEF2 family of transcription factors. In mammals, four MEF2A-related genes encode proteins which exhibit significant amino acid sequence similarity within their DNA binding domains and to a lesser extent throughout the remaining proteins. The MEF2 family members were originally described as muscle-specific DNA binding proteins that recognize MEF2 motifs found within the promoters of many muscle-specific genes. Phosphorylation of MEF2A at Thr312 and Thr319 within the transcription activation domain by p38 MAP kinase enhances MEF2A-MEF2D heterodimer-dependent gene expression. On the other hand, apoptotic stimuli result in CDK5-dependent phosphorylation of MEF2A at Ser408 within the activation domain, inhibiting MEF2A pro-survival function.
References
[1] Shore, P. et al. (1995) Eur. J. Biochem. 229, 1-13.
[2] Martin, J.F. et al. (1994) Mol. Cell. Biol. 14, 1647-1656.
[3] Yu, Y.T. et al. (1992) Genes Dev. 6, 1783-1798.
[4] Zhao, M. et al. (1999) Mol. Cell. Biol. 19, 21-30.
[5] Gong, X. et al. (2003) Neuron 38, 33-46.
MEF2A antibody Preparation Products And Raw materials
Raw materials
Preparation Products
MEF2A antibody Suppliers
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