TRAF1 (45D3) Rabbit mAb
Source Reactivity Background References- Product Name
- TRAF1 (45D3) Rabbit mAb
- Chemical Name
- TRAF1 (45D3) Rabbit mAb
- Synonyms
- TRAF1 (45D3) Rabbit mAb
- CBNumber
- CB55701914
- Formula Weight
- 0
- MOL File
- Mol file
TRAF1 (45D3) Rabbit mAb Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human
Background
TRAFs are a family of multifunctional adaptor proteins that bind to surface receptors and recruit additional proteins to form multiprotein signaling complexes capable of promoting cellular responses. Members of the TRAF family share a common carboxy-terminal "TRAF domain", which mediates interactions with associated proteins; many also contain amino-terminal Zinc/RING finger motifs. The first TRAFs identified, TRAF1 and TRAF2, were found by virtue of their interactions with the cytoplasmic domain of TNF-receptor 2. The six known TRAFs act as adaptor proteins for a wide range of cell surface receptors and participate in the regulation of cell survival, proliferation, differentiation, and stress responses.
References
[1] Arch, R.H. et al. (1998) Genes Dev 12, 2821-30.
[2] Chung, J.Y. et al. (2002) J Cell Sci 115, 679-88.
[3] Bradley, J.R. and Pober, J.S. (2001) Oncogene 20, 6482-91.
[4] Rothe, M. et al. (1994) Cell 78, 681-92.
TRAF1 (45D3) Rabbit mAb Preparation Products And Raw materials
Raw materials
Preparation Products
TRAF1 (45D3) Rabbit mAb Suppliers
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- 13247685458
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