N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine
- Product Name
- N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine
- CAS No.
- 93285-75-7
- Chemical Name
- N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine
- Synonyms
- Iaa-Biotin;IODOACETYL LC BIOTIN;Biotin-C6-iodoacetamide;N-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE;N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE;N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine;N-BIOTINYL-N'-(IODOACETYL)-1,6-HEXANEDIAMINE;N-Biotinyl-Na€-(iodoacetyl)-1,6-hexanediamine;N-Iodoacetyl-N-biotinylhexylenediaMine(Iodoacetyl-LC-Biotin);(3aS,4S,6aR)-Hexahydro-N-[6-[(iodoacetyl)amino]hexyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
- CBNumber
- CB5664328
- Molecular Formula
- C18H31IN4O3S
- Formula Weight
- 510.43
- MOL File
- 93285-75-7.mol
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Property
- Boiling point:
- 793.7±60.0 °C(Predicted)
- Density
- 1.414±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- ≥51 mg/mL in DMSO with gentle warming; insoluble in EtOH; insoluble in H2O
- form
- solid
- pka
- 13.90±0.40(Predicted)
- color
- White to off-white
Safety
- Hazard Codes
- Xi
- HS Code
- 2928009090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
N-Bromosuccinimide Price
- Product number
- B396025
- Product name
- N-Biotinyl-N’-(iodoacetyl)-1,6-hexanediamine
- Packaging
- 50mg
- Price
- $560
- Updated
- 2021/12/16
- Product number
- HCH0009003
- Product name
- N-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $715.75
- Updated
- 2021/12/16
- Product number
- A8009
- Product name
- Iodoacetyl-LC-Biotin
- Packaging
- 100mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- BP-22638
- Product name
- Iodoacetyl-LC-Biotin
- Purity
- 97%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BP-22638
- Product name
- Iodoacetyl-LC-Biotin
- Purity
- 97%
- Packaging
- 250mg
- Price
- $560
- Updated
- 2021/12/16
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Chemical Properties,Usage,Production
Description
iodoacetyll-LC-Biotin is a sulfhydryl-reactive biotinylation reagent that forms stable, irreversible thioether bonds when reacting with with sulfhydryls (-SH) group at alkaline pH. The hexylenediamine spacer arm gives this reagent the membrane-impermeability which enables intracellular labeling of biomolecules.
Uses
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine can be a useful reagent for biotinylation of proteins and subsequent use in a protein microarray.
Uses
amine reactive biotinylation reagent
Biological Activity
iodoacetyl-lc-biotin (n-iodoacetyl-n-biotinylhexylenediamine), a sulfhydryl-reactive biotinylation agent, is a water-insoluble reagent that requires the dissolution of suitable solvents, including dimethyl sulfoxide (dmso) and dimethylformamide (dmf), prior to the addition into aqueous reactions. iodoacetyl-lc-biotin consists of a bicyclic biotin rings structure, a 1,6-diaminohexane spacer group attached to the valeric acid side chain of biotin and an iodoacetyl group at the end of the spacer providing sulfhydryl reactivity. the iodoacetyl group at the end of iodoacetyl-lc-biotin is able to react with sulfhydryl groups on proteins and other molecules forming a nonreversible bond. the long spacer arm of iodoacetyl-lc-biotin enables the modified molecule to better bind to the avidin or streptavidin probes.bioconjugate techniques , 2nd ed. by greg t.hermanson (pierce biotechnology, thermo fisher scientific, rockford, il). academic press (an imprint of elsevier): london, amsterdam, burlington, san diego . 2008. isbn 978-0-12-370501-3.
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Preparation Products And Raw materials
Raw materials
Preparation Products
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71
View Lastest Price from N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine manufacturers
- Product
- Biotin-C6-iodoacetamide 93285-75-7
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >95.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-30