3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL

Product Name: 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
CAS No.: 214360-76-6
Chemical Name: 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
Synonyms: 132347;522562_Aldrich;Pinacol cyclic ester;2-DIOXABOROLAN-2-YL)PHENOL;3-Hydroxyphenylboronic acid pinacol este;3-HYDROXYBENZENEBORONIC ACID PINACOL ESTER;3-HYDROXYPHENYLBORONIC ACID, PINACOL ESTER;3-(tetraMethyl-1,3,2-dioxaborolan-2-yl)phenol;3-Hydroxybenzeneboronic acid, pinacol ester 98%;3-HYDROXYPHENYLBORONIC ACID, PINACOL CYCLIC ESTER
CBNumber: CB5667617
Molecular Formula: C12H17BO3
Formula Weight: 220.07
MOL File: 214360-76-6.mol

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3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Property

Melting point:: 94-98 °C(lit.)
Boiling point:: 343.6±25.0 °C(Predicted)
Density: 1.08±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Water Solubility: Insoluble in water
pka: 10.01±0.10(Predicted)
form: Crystalline Powder
color: Light brown
InChI: InChI=1S/C12H17BO3/c1-11(2)12(3,4)16-13(15-11)9-6-5-7-10(14)8-9/h5-8,14H,1-4H3
InChIKey: MUKIFYQKIZOYKT-UHFFFAOYSA-N
SMILES: C1(O)=CC=CC(B2OC(C)(C)C(C)(C)O2)=C1
CAS DataBase Reference: 214360-76-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
TSCA: No
HazardClass: IRRITANT
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 522562
Product name: 3-Hydroxyphenylboronic acid pinacol ester
Purity: 97%
Packaging: 5g
Price: $185.5
Updated: 2025/07/31

Sigma-Aldrich

Product number: 522562
Product name: 3-Hydroxyphenylboronic acid pinacol ester
Purity: 97%
Packaging: 1g
Price: $85.4
Updated: 2023/06/20

TCI Chemical

Product number: T1953
Product name: 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
Purity: >98.0%(GC)
Packaging: 1g
Price: $65
Updated: 2025/07/31

TCI Chemical

Product number: T1953
Product name: 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
Purity: >98.0%(GC)
Packaging: 5g
Price: $220
Updated: 2025/07/31

Strem Chemicals

Product number: 05-1043
Product name: 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, min. 97%
Packaging: 1g
Price: $101
Updated: 2024/03/01

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3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Chemical Properties,Usage,Production

Chemical Properties

light brown crystalline powder

Uses

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

76-09-5

87199-18-6

214360-76-6

The general procedure for the synthesis of 3-hydroxyphenylboronic acid pinacol ester from pinacol and 3-hydroxyphenylboronic acid was as follows: 3-hydroxyphenylboronic acid (10.0 g, 72.46 mmol, 1.0 eq.) and dichloromethane (300 mL) were added to a 500 mL three-necked flask with pinacol (10.0 g, 84.60 mmol, 1.2 eq.) under stirring. Subsequently, the reaction mixture was stirred continuously for 48 hours at room temperature. Upon completion of the reaction, the reaction solution was poured into water (400 mL) and transferred to a partition funnel for separation. After separation of the organic phase, the aqueous phase was extracted twice with dichloromethane (400 mL). All organic phases were combined, dried with anhydrous sodium sulfate and filtered to remove the desiccant. The crude product was purified by column chromatography (using 200-300 mesh silica gel and a solvent mixture of dichloromethane/methanol as eluent, 100:1, v/v), resulting in 15.0 g of white solid product in 94% yield and 97% purity.

References

[1] Patent: CN107188901, 2017, A. Location in patent: Paragraph 0035; 0036
[2] Organic Letters, 2010, vol. 12, # 23, p. 5474 - 5477

3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Suppliers

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View Lastest Price from 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL 214360-76-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL 214360-76-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL 214360-76-6
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: ask
Release date: 2018-12-20

214360-76-6, 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOLRelated Search:

2-(3-Hydroxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 3-Hydroxyphenylboronic Acid Pinacol Ester

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol 3-Hydroxyphenylboronic Acid

522562_Aldrich

3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL

2-(3-HYDROXYPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE

3-HYDROXYBENZENEBORONIC ACID PINACOL ESTER

3-HYDROXYPHENYLBORONIC ACID, PINACOL CYCLIC ESTER

3-HYDROXYPHENYLBORONIC ACID, PINACOL ESTER

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol,min.97%

3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL, MIN. 97%

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, 3-Hydroxyphenylboronic acid, Pinacol cyclic ester

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol,97%

3-Hydroxyphenylboronic acid pinacol este

Pinacol cyclic ester

2-DIOXABOROLAN-2-YL)PHENOL

3-(tetraMethyl-1,3,2-dioxaborolan-2-yl)phenol

(3-hydroxy-2,3-dimethylbutan-2-yl)oxy-(3-hydroxyphenyl)borinic acid

3-Hydroxybenzeneboronic acid, pinacol ester 98%

132347

Phenol, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

214360-76-6

Boronic Acids Esters

B (Classes of Boron Compounds)

Organometallic Reagents

Aryl

Boronate Esters

Boronic Acids and Derivatives

BORONIC ACID

Aryl Boronate Esters

Boronate Esters

Boronic Acids and Derivatives

Chemical Synthesis

Organometallic Reagents

Isoxazoles ,Oxazoles

organic or inorganic borate

B (Classes of Boron Compounds)

Boronic Acids Esters

Boronic acids