3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
- Product Name
- 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
- CAS No.
- 214360-76-6
- Chemical Name
- 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
- Synonyms
- 132347;522562_Aldrich;Pinacol cyclic ester;2-DIOXABOROLAN-2-YL)PHENOL;3-Hydroxyphenylboronic acid pinacol este;3-HYDROXYBENZENEBORONIC ACID PINACOL ESTER;3-HYDROXYPHENYLBORONIC ACID, PINACOL ESTER;3-(tetraMethyl-1,3,2-dioxaborolan-2-yl)phenol;3-Hydroxybenzeneboronic acid, pinacol ester 98%;3-HYDROXYPHENYLBORONIC ACID, PINACOL CYCLIC ESTER
- CBNumber
- CB5667617
- Molecular Formula
- C12H17BO3
- Formula Weight
- 220.07
- MOL File
- 214360-76-6.mol
3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Property
- Melting point:
- 94-98 °C(lit.)
- Boiling point:
- 343.6±25.0 °C(Predicted)
- Density
- 1.08±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Water Solubility
- Insoluble in water
- pka
- 10.01±0.10(Predicted)
- form
- Crystalline Powder
- color
- Light brown
- InChI
- InChI=1S/C12H17BO3/c1-11(2)12(3,4)16-13(15-11)9-6-5-7-10(14)8-9/h5-8,14H,1-4H3
- InChIKey
- MUKIFYQKIZOYKT-UHFFFAOYSA-N
- SMILES
- C1(O)=CC=CC(B2OC(C)(C)C(C)(C)O2)=C1
- CAS DataBase Reference
- 214360-76-6(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 522562
- Product name
- 3-Hydroxyphenylboronic acid pinacol ester
- Purity
- 97%
- Packaging
- 5g
- Price
- $185.5
- Updated
- 2025/07/31
- Product number
- 522562
- Product name
- 3-Hydroxyphenylboronic acid pinacol ester
- Purity
- 97%
- Packaging
- 1g
- Price
- $85.4
- Updated
- 2023/06/20
- Product number
- T1953
- Product name
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $65
- Updated
- 2025/07/31
- Product number
- T1953
- Product name
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $220
- Updated
- 2025/07/31
- Product number
- 05-1043
- Product name
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, min. 97%
- Packaging
- 1g
- Price
- $101
- Updated
- 2024/03/01
3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Chemical Properties,Usage,Production
Chemical Properties
light brown crystalline powder
Uses
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
76-09-5
87199-18-6
214360-76-6
The general procedure for the synthesis of 3-hydroxyphenylboronic acid pinacol ester from pinacol and 3-hydroxyphenylboronic acid was as follows: 3-hydroxyphenylboronic acid (10.0 g, 72.46 mmol, 1.0 eq.) and dichloromethane (300 mL) were added to a 500 mL three-necked flask with pinacol (10.0 g, 84.60 mmol, 1.2 eq.) under stirring. Subsequently, the reaction mixture was stirred continuously for 48 hours at room temperature. Upon completion of the reaction, the reaction solution was poured into water (400 mL) and transferred to a partition funnel for separation. After separation of the organic phase, the aqueous phase was extracted twice with dichloromethane (400 mL). All organic phases were combined, dried with anhydrous sodium sulfate and filtered to remove the desiccant. The crude product was purified by column chromatography (using 200-300 mesh silica gel and a solvent mixture of dichloromethane/methanol as eluent, 100:1, v/v), resulting in 15.0 g of white solid product in 94% yield and 97% purity.
References
[1] Patent: CN107188901, 2017, A. Location in patent: Paragraph 0035; 0036
[2] Organic Letters, 2010, vol. 12, # 23, p. 5474 - 5477
3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Preparation Products And Raw materials
Raw materials
Preparation Products
3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Suppliers
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View Lastest Price from 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL manufacturers
- Product
- 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL 214360-76-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL 214360-76-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL 214360-76-6
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- ask
- Release date
- 2018-12-20