3-Hydroxyphenylboronic acid

Product Name: 3-Hydroxyphenylboronic acid
CAS No.: 87199-18-6
Chemical Name: 3-Hydroxyphenylboronic acid
Synonyms: AKOS BRN-0182;3-boronophenol;RARECHEM AH PB 0221;3-Hydroxyphenylboron;3-Hydroxyphenylboronic;3-hydroxyphenylboric acid;N-fluorodiphenylsulfonamide;3-HYDROXYPHENYLBORONIC ACID;M-HYDROXYPHENYLBORONIC ACID;3-HYDROXYBENZENEBORONIC ACID
CBNumber: CB4204923
Molecular Formula: C6H7BO3
Formula Weight: 137.93
MOL File: 87199-18-6.mol

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3-Hydroxyphenylboronic acid Property

Melting point:: 210-213 °C (dec.) (lit.)
Boiling point:: 370.0±44.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Crystalline Powder, Crystals and/or Chunks
pka: pK1:8.55;pK2:10.84 (25°C)
color: Pink to gray to tan
BRN: 3240771
InChI: InChI=1S/C6H7BO3/c8-6-3-1-2-5(4-6)7(9)10/h1-4,8-10H
InChIKey: WFWQWTPAPNEOFE-UHFFFAOYSA-N
SMILES: B(C1=CC=CC(O)=C1)(O)O
CAS DataBase Reference: 87199-18-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-22
Safety Statements: 37/39-26-36/37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 523968
Product name: 3-Hydroxyphenylboronic acid
Purity: ≥95.0%
Packaging: 1g
Price: $54.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: 523968
Product name: 3-Hydroxyphenylboronic acid
Purity: ≥95.0%
Packaging: 10g
Price: $103
Updated: 2025/07/31

TCI Chemical

Product number: H1185
Product name: 3-Hydroxyphenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 1g
Price: $20
Updated: 2025/07/31

TCI Chemical

Product number: H1185
Product name: 3-Hydroxyphenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 5g
Price: $60
Updated: 2025/07/31

TRC

Product number: H952918
Product name: 3-Hydroxyphenylboronic acid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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3-Hydroxyphenylboronic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

suzuki reaction

Uses

3-Hydroxyphenylboronic acid (3-HPBA) can be used as a reagent:

In Suzuki-Miyaura coupling reactions with aryl halides for the formation of C-C bond in the presence of Pd catalyst.
?To synthesize boron/nitrogen-doped polymer nano/microspheres by hydrothermal polymerization with formaldehyde and ammonia.??????
To prepare carbon quantum dots based on 3-HPBA as selective fructose sensor.?????
In the development of modified electrodes for electrochemical biosensors.

Synthesis

121-43-7

591-20-8

87199-18-6

(vi) Preparation of 3-hydroxyphenylboronic acid: m-Bromophenol (8.65 g, 50 mmol) was dissolved in anhydrous tetrahydrofuran (150 mL) and sodium hydride (60%, 2.4 g, 60 mmol) was added at room temperature. After 1 hour of reaction, sec-butyl lithium (1.3 M, 50 mL, 65 mmol) was added slowly and dropwise to the reaction solution at -78 °C. Stirring was continued at this temperature for 30 min, followed by the addition of trimethyl borate (15 mL). The reaction system was gradually warmed to room temperature and maintained for 2 hours. Upon completion of the reaction, the reaction was quenched with deionized water (50 mL) and extracted with dichloromethane (2 x 100 mL). The organic phases were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to afford 3-hydroxyphenylboronic acid as a white solid (4.0 g, 58% yield), and the product was used directly in the subsequent Suzuki coupling reaction without further purification.

References

[1] Patent: US2003/187022, 2003, A1

3-Hydroxyphenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Hydroxyphenylboronic acid Suppliers

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View Lastest Price from 3-Hydroxyphenylboronic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 3-Hydroxyphenylboronic acid 87199-18-6
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-25

Henan Fengda Chemical Co., Ltd

Product: 3-Hydroxyphenylboronic acid 87199-18-6
Price: US $34.00-1.20/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

Hebei Xinsheng New Material Technology Co., LTD.

Product: 3-Hydroxyphenylboronic acid 87199-18-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 30000 Kg
Release date: 2023-11-30

87199-18-6, 3-Hydroxyphenylboronic acidRelated Search:

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3-Hydroxyphenylboronic acid, May contain varying amounts of anhydride, 97%

m-Hydroxybenzeneboronic acid

3-Hydroxyphenylboronic acid >=95.0%

B-(3-hydroxy-phenyl)boronic acid

BORONICACID, B-(3-HYDROXYPHENYL)-

3-Hydroxybenzeneboronic Acid 3-Boronophenol

3-HYDROXYBENZENEBORONIC ACID

3-HYDROXYPHENYLBORONIC ACID

AKOS BRN-0182

RARECHEM AH PB 0221

M-HYDROXYPHENYLBORONIC ACID

3-Boronophenol~3-Hydroxyphenylboronic acid

3-Hydroxybenzeneboronicacid,97%

3-Hydroxyphenylboronic

3-boronophenol

3-hydroxyphenylboric acid

3-HYDROXYPHENYLBORONIC ACID 97%

3-Hydroxybenzeneboronic acid 98%

3-Hydroxyphenylboron

3-Hydroxyphenylboronic acid - [H3740]

87199-18-6

97199-18-6

HOC6H4BOH2

Organometallic Reagents

Boronic Acids

Boronic Acids and Derivatives

Aryl

Substituted Boronic Acids

blocks

BoronicAcids

Boronate Ester

Potassium Trifluoroborate

Boronic Acids & Esters

Phenyls & Phenyl-Het

Organic acids

Boronic Acid

B (Classes of Boron Compounds)

Boronic Acids

Boronic Acids & Esters

Phenyls & Phenyl-Het

Boronic Acids

Boronic Acids and Derivatives

Aryl

Organoborons