3-Methoxyphenylboronic acid
- Product Name
- 3-Methoxyphenylboronic acid
- CAS No.
- 10365-98-7
- Chemical Name
- 3-Methoxyphenylboronic acid
- Synonyms
- AKOS BRN-0015;3-boronoanisole;RARECHEM AH PB 0180;3-Methoxyphenylboron;M-Anisylboronic Acid;M-METHOXY PHENYLBORIC;3-Methoxyphenylboronic;Anisole-3-boronic acid;3 Anisole Boronic Acid;3-Methoxyphenylboric acid
- CBNumber
- CB4212548
- Molecular Formula
- C7H9BO3
- Formula Weight
- 151.96
- MOL File
- 10365-98-7.mol
3-Methoxyphenylboronic acid Property
- Melting point:
- 160-163 °C (lit.)
- Boiling point:
- 318.6±44.0 °C(Predicted)
- Density
- 1.17±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 8.10±0.10(Predicted)
- form
- Crystalline Powder
- color
- White to light beige
- BRN
- 2831223
- InChI
- InChI=1S/C7H9BO3/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5,9-10H,1H3
- InChIKey
- NLLGFYPSWCMUIV-UHFFFAOYSA-N
- SMILES
- B(C1=CC=CC(OC)=C1)(O)O
- CAS DataBase Reference
- 10365-98-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 441686
- Product name
- 3-Methoxyphenylboronic acid
- Packaging
- 1g
- Price
- $56.3
- Updated
- 2025/07/31
- Product number
- 441686
- Product name
- 3-Methoxyphenylboronic acid
- Packaging
- 10g
- Price
- $175
- Updated
- 2023/06/20
- Product number
- M1322
- Product name
- 3-Methoxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 1g
- Price
- $16
- Updated
- 2025/07/31
- Product number
- M1322
- Product name
- 3-Methoxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 5g
- Price
- $44
- Updated
- 2025/07/31
- Product number
- M1322
- Product name
- 3-Methoxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 25g
- Price
- $131
- Updated
- 2025/07/31
3-Methoxyphenylboronic acid Chemical Properties,Usage,Production
Chemical Properties
3-Methoxyphenylboronic acid is a white to light yellow crystal powder, irritating.
Uses
suzuki reaction
Uses
3-Methoxyphenylboronic Acid is a phenylboronic acid used to investigate boron function in plants.
Synthesis
2398-37-0
121-43-7
10365-98-7
Phase I: Synthesis of 3-methoxyphenylboronic acid 1. 41.3 g (220 mmol) of m-bromoanisole was dissolved in 880 mL of tetrahydrofuran under nitrogen protection and the solution was cooled to -70 °C in an ethanol/dry ice cooling bath. 2. 160 mL (250 mmol) of butyllithium solution (1.6 M in hexane) was added slowly dropwise, with the rate of acceleration of the drop being controlled to ensure that the reaction temperature did not exceed -60 °C. 3. After stirring the reaction mixture continuously for 1.5 hours at -70 °C, slowly add 75 mL (660 mmol) of trimethyl borate dropwise, again controlling the temperature to not exceed -60 °C. 4. 4. After the dropwise addition, the reaction mixture was continued to be stirred for 1 hour under cooling conditions. 5. The reaction mixture was slowly warmed to 25 °C over a period of 2 hours, followed by the addition of 720 mL of 1 M hydrochloric acid and stirring at 25 °C for 15 hours. 6. Upon completion of the reaction, post-treatment was performed: the reaction mixture was extracted with 300 mL of ether, repeated three times, and the organic phases were combined. 7. The combined organic phases were washed sequentially with 100 mL of water and saturated sodium chloride solution, then dried with anhydrous magnesium sulfate and filtered. 8. The filtrate was concentrated on a rotary evaporator (pressure controlled at 500-10 mbar) to give 30.8 g of 3-methoxyphenylboronic acid in 92.1% yield of the theoretical value.
References
[1] Patent: US2002/198251, 2002, A1
[2] Tetrahedron Letters, 2012, vol. 53, # 46, p. 6182 - 6185,4
[3] Journal of the Chemical Society - Perkin Transactions 1, 1999, # 17, p. 2513 - 2523
[4] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 9, p. 1919 - 1922
3-Methoxyphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Methoxyphenylboronic acid Suppliers
- Tel
- 022-83719186 13212251377
- Fax
- 086-022-8789 9925
- 18522618860@163.com
- Country
- China
- ProdList
- 79
- Advantage
- 55
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
View Lastest Price from 3-Methoxyphenylboronic acid manufacturers
- Product
- 3-Methoxyphenylboronic acid 10365-98-7
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-05
- Product
- 3-Methoxyphenylboronic acid 10365-98-7
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20TONS
- Release date
- 2024-05-24
- Product
- 3-Methoxyphenylboronic acid 10365-98-7
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 200000
- Release date
- 2023-12-27