3-Hydroxyphenylboronic acid
- Product Name
- 3-Hydroxyphenylboronic acid
- CAS No.
- 87199-18-6
- Chemical Name
- 3-Hydroxyphenylboronic acid
- Synonyms
- AKOS BRN-0182;3-boronophenol;RARECHEM AH PB 0221;3-Hydroxyphenylboron;3-Hydroxyphenylboronic;3-hydroxyphenylboric acid;N-fluorodiphenylsulfonamide;3-HYDROXYPHENYLBORONIC ACID;M-HYDROXYPHENYLBORONIC ACID;3-HYDROXYBENZENEBORONIC ACID
- CBNumber
- CB4204923
- Molecular Formula
- C6H7BO3
- Formula Weight
- 137.93
- MOL File
- 87199-18-6.mol
3-Hydroxyphenylboronic acid Property
- Melting point:
- 210-213 °C (dec.) (lit.)
- Boiling point:
- 370.0±44.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Crystalline Powder, Crystals and/or Chunks
- pka
- pK1:8.55;pK2:10.84 (25°C)
- color
- Pink to gray to tan
- BRN
- 3240771
- InChI
- InChI=1S/C6H7BO3/c8-6-3-1-2-5(4-6)7(9)10/h1-4,8-10H
- InChIKey
- WFWQWTPAPNEOFE-UHFFFAOYSA-N
- SMILES
- B(C1=CC=CC(O)=C1)(O)O
- CAS DataBase Reference
- 87199-18-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-22
- Safety Statements
- 37/39-26-36/37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 523968
- Product name
- 3-Hydroxyphenylboronic acid
- Purity
- ≥95.0%
- Packaging
- 1g
- Price
- $54.7
- Updated
- 2025/07/31
- Product number
- 523968
- Product name
- 3-Hydroxyphenylboronic acid
- Purity
- ≥95.0%
- Packaging
- 10g
- Price
- $103
- Updated
- 2025/07/31
- Product number
- H1185
- Product name
- 3-Hydroxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 1g
- Price
- $20
- Updated
- 2025/07/31
- Product number
- H1185
- Product name
- 3-Hydroxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 5g
- Price
- $60
- Updated
- 2025/07/31
- Product number
- H952918
- Product name
- 3-Hydroxyphenylboronic acid
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
3-Hydroxyphenylboronic acid Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
suzuki reaction
Uses
3-Hydroxyphenylboronic acid (3-HPBA) can be used as a reagent:
- In Suzuki-Miyaura coupling reactions with aryl halides for the formation of C-C bond in the presence of Pd catalyst.
- ?To synthesize boron/nitrogen-doped polymer nano/microspheres by hydrothermal polymerization with formaldehyde and ammonia.??????
- To prepare carbon quantum dots based on 3-HPBA as selective fructose sensor.?????
- In the development of modified electrodes for electrochemical biosensors.
Synthesis
121-43-7
591-20-8
87199-18-6
(vi) Preparation of 3-hydroxyphenylboronic acid: m-Bromophenol (8.65 g, 50 mmol) was dissolved in anhydrous tetrahydrofuran (150 mL) and sodium hydride (60%, 2.4 g, 60 mmol) was added at room temperature. After 1 hour of reaction, sec-butyl lithium (1.3 M, 50 mL, 65 mmol) was added slowly and dropwise to the reaction solution at -78 °C. Stirring was continued at this temperature for 30 min, followed by the addition of trimethyl borate (15 mL). The reaction system was gradually warmed to room temperature and maintained for 2 hours. Upon completion of the reaction, the reaction was quenched with deionized water (50 mL) and extracted with dichloromethane (2 x 100 mL). The organic phases were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to afford 3-hydroxyphenylboronic acid as a white solid (4.0 g, 58% yield), and the product was used directly in the subsequent Suzuki coupling reaction without further purification.
References
[1] Patent: US2003/187022, 2003, A1
3-Hydroxyphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Hydroxyphenylboronic acid Suppliers
- Tel
- 800-4238616
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- +1-888-520-1075 / +1-503-283-1987
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- Americas
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View Lastest Price from 3-Hydroxyphenylboronic acid manufacturers
- Product
- 3-Hydroxyphenylboronic acid 87199-18-6
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-25
- Product
- 3-Hydroxyphenylboronic acid 87199-18-6
- Price
- US $34.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 3-Hydroxyphenylboronic acid 87199-18-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 30000 Kg
- Release date
- 2023-11-30