DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)

Product Name: DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)
CAS No.: 85272-30-6
Chemical Name: DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)
Synonyms: DK412;diisopropylbis(trifluoromethanesulfonyl)silane;DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE);Diisopropylsilylenebis(trifluoromethanesulfonate);TRIFLUOROMETHANESULFONIC ACID DIISOPROPYLSILYLENE ESTER;DIISOPROPYLSILYL BIS(TRIFLUOROMETHANE-SU LFONATE), TECH.;Bis(trifluoromethanesulfonic acid)diisopropylsilanediyl ester;Bis(1-methylethyl)[[(trifluoromethyl)sulfonyl]oxy]silyl triflate;Methanesulfonic acid, trifluoro-, bis(1-methylethyl)silylene ester;Methanesulfonic acid, 1,1,1-trifluoro-, bis(1-methylethyl)[[(trifluoromethyl)sulfonyl]oxy]silyl ester
CBNumber: CB5678556
Molecular Formula: C8H14F6O6S2Si
Formula Weight: 412.4
MOL File: 85272-30-6.mol

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DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) Property

Boiling point:: 85-86 °C2 mm Hg(lit.)
Density: 1.396 g/mL at 25 °C(lit.)
refractive index: n20/D 1.382(lit.)
Flash point:: >230 °F
form: liquid
Specific Gravity: 1.396
Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents
BRN: 3567500

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Safety

Hazard Codes: C
Risk Statements: 34-37
Safety Statements: 26-36/37/39-45
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
F: 10-21
HazardClass: 8
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 375942
Product name: Diisopropylsilyl bis(trifluoromethanesulfonate)
Purity: 96%
Packaging: 5g
Price: $123
Updated: 2024/03/01

Sigma-Aldrich

Product number: 375942
Product name: Diisopropylsilyl bis(trifluoromethanesulfonate)
Purity: 96%
Packaging: 25g
Price: $559
Updated: 2023/06/20

Biosynth Carbosynth

Product number: FD90402
Product name: Diisopropylsilyl Bis(Trifluoromethanesulfonate)
Packaging: 25g
Price: $875
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD90402
Product name: Diisopropylsilyl Bis(Trifluoromethanesulfonate)
Packaging: 5G
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD90402
Product name: Diisopropylsilyl Bis(Trifluoromethanesulfonate)
Packaging: 10g
Price: $400
Updated: 2021/12/16

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DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) Chemical Properties,Usage,Production

Physical properties

bp 85–86°C/2mmHg;d 1.396 g cm?3; fp 110°C.

Uses

Diisopropylsilyl bis(trifluoromethanesulfonate) has more recently been used to prepare diisopropylsilyl-linked oligonucleotide analogs. Silylation of 5'-O-(dimethoxytrityl)-2'-deoxynucleosides using diisopropylsilyl bis(trifluoromethanesulfonate) and the hindered base 2,6-di-t-butyl-4-methylpyridine (Dtbp) provided quantitative yield of 3'-O-diisopropylsilanols (eq 2). Hence, silylation of 5'-O-(dimethoxytrityl)thymidine, N6-benzoyl-2'-deoxy-5'-O- (dimethoxytrityl)adenosine, N4-benzoyl-2'-deoxy-5'-O-(dimethoxytrityl) cytidine, and N2-isobutyryl-2'-deoxy-5'-O-(dimethoxytrityl) guanosine gave the desired products 5a–d in excellent yields.
Coupling of products 5a–d with unprotected thymidine resulted in formation of 3',5'-linked dinucleosides 6a–d selectively, and the dimer 7 from reaction with secondary hydroxyl group of thymidine was not observed (eq 3). Subsequent silylation and coupling with another molecule of thymidine gave 3,5- linked trinucleoside 8 in 76% yield (eq 4). A tetrathymidylate oligomer was prepared by 3'-O-silylation of 8 followed by coupling with thymidine. Although no self-condensation was observed, only 30% of the product 9 was obtained after purification by preparative HPLC.

Preparation

conveniently prepared by the slow addition of 2 equiv of trifluoromethanesulfonic acid to a stirring mixture of chlorodiisopropylsilane, followed by direct distillation of the product from the reaction flask to yield the product as a pale yellow oil.

storage

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) should be stored in the refrigerator under an inert atmosphere of argon or nitrogen. Special care should be used when handling since diisopropysilyl bis(trifluoromethanesulfonate) has been classified as a corrosive.

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) Preparation Products And Raw materials

Raw materials

Preparation Products

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DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) Suppliers

China 34 India 1 Switzerland 1 United Kingdom 2 United States 5 Global 43

Meryer (Shanghai) Chemical Technology Co., Ltd.

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Tianjin heowns Biochemical Technology Co., Ltd.

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Shanghai Worldyang Chemical Co.,Ltd.

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Sigma-Aldrich

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Shanghai Zhuang Ming New Material Technology Co., Ltd.

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Shanghai Synchem Pharma Co., ltd

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Xuzhou ZhuoYun New Material Technology Co., Ltd.

Tel: 0516- 13776763863
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View Lastest Price from DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) manufacturers

Career Henan Chemical Co

Product: diisopropylbis(trifluoromethanesulfonyl)silane 85272-30-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98%
Supply Ability: g/kg/ton
Release date: 2020-01-08

85272-30-6, DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)Related Search:

RUETASOLV BP 4201 (DIISOPROPYLBIPHENYL MIXTURE OF ISOMERES) SPECIALITY CHEMICALS Trifluoromethane DIMETHYLBIS(TRIFLUOROMETHYLSULFONYLOXY)SILANE DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) DI-TERT-BUTYLSILYL BIS(TRIFLUOROMETHANESULFONATE) DIISOPROPYLSILANE

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)

TRIFLUOROMETHANESULFONIC ACID DIISOPROPYLSILYLENE ESTER

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANE-SU LFONATE), TECH.

diisopropylbis(trifluoromethanesulfonyl)silane

Bis(trifluoromethanesulfonic acid)diisopropylsilanediyl ester

Diisopropylsilylenebis(trifluoromethanesulfonate)

Methanesulfonic acid, trifluoro-, bis(1-methylethyl)silylene ester

Methanesulfonic acid, 1,1,1-trifluoro-, bis(1-methylethyl)[[(trifluoromethyl)sulfonyl]oxy]silyl ester

DK412

Bis(1-methylethyl)[[(trifluoromethyl)sulfonyl]oxy]silyl triflate

85272-30-6

C8H14F6O6S2Si

CF3SO32SiCHCH322

Protection and Derivatization

Protecting and Derivatizing Reagents

Silicon-Based

Synthetic Reagents