DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)

Product Name: DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)
CAS No.: 85272-30-6
Chemical Name: DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)
Synonyms: DK412;diisopropylbis(trifluoromethanesulfonyl)silane;DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE);Diisopropylsilylenebis(trifluoromethanesulfonate);Diisopropylsilanediyl bis(trifluoromethanesulfonate);TRIFLUOROMETHANESULFONIC ACID DIISOPROPYLSILYLENE ESTER;DIISOPROPYLSILYL BIS(TRIFLUOROMETHANE-SU LFONATE), TECH.;Bis(trifluoromethanesulfonic acid)diisopropylsilanediyl ester;Bis(1-methylethyl)[[(trifluoromethyl)sulfonyl]oxy]silyl triflate;Methanesulfonic acid, trifluoro-, bis(1-methylethyl)silylene ester
CBNumber: CB5678556
Molecular Formula: C8H14F6O6S2Si
Formula Weight: 412.4
MOL File: 85272-30-6.mol

More

Less

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) Property

Boiling point:: 85-86 °C2 mm Hg(lit.)
Density: 1.396 g/mL at 25 °C(lit.)
refractive index: n20/D 1.382(lit.)
Flash point:: >230 °F
form: liquid
Specific Gravity: 1.396
Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents
BRN: 3567500

More

Less

Safety

Hazard Codes: C
Risk Statements: 34-37
Safety Statements: 26-36/37/39-45
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
F: 10-21
HazardClass: 8
PackingGroup: III

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 375942
Product name: Diisopropylsilyl bis(trifluoromethanesulfonate)
Purity: 96%
Packaging: 5g
Price: $127
Updated: 2025/07/31

Sigma-Aldrich

Product number: 375942
Product name: Diisopropylsilyl bis(trifluoromethanesulfonate)
Purity: 96%
Packaging: 25g
Price: $559
Updated: 2023/06/20

Biosynth Carbosynth

Product number: FD90402
Product name: Diisopropylsilyl Bis(Trifluoromethanesulfonate)
Packaging: 1g
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD90402
Product name: Diisopropylsilyl Bis(Trifluoromethanesulfonate)
Packaging: 2g
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD90402
Product name: Diisopropylsilyl Bis(Trifluoromethanesulfonate)
Packaging: 5G
Price: $250
Updated: 2021/12/16

More

Less

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) Chemical Properties,Usage,Production

Physical properties

bp 85–86°C/2mmHg;d 1.396 g cm?3; fp 110°C.

Uses

Diisopropylsilyl bis(trifluoromethanesulfonate) has more recently been used to prepare diisopropylsilyl-linked oligonucleotide analogs. Silylation of 5'-O-(dimethoxytrityl)-2'-deoxynucleosides using diisopropylsilyl bis(trifluoromethanesulfonate) and the hindered base 2,6-di-t-butyl-4-methylpyridine (Dtbp) provided quantitative yield of 3'-O-diisopropylsilanols (eq 2). Hence, silylation of 5'-O-(dimethoxytrityl)thymidine, N6-benzoyl-2'-deoxy-5'-O- (dimethoxytrityl)adenosine, N4-benzoyl-2'-deoxy-5'-O-(dimethoxytrityl) cytidine, and N2-isobutyryl-2'-deoxy-5'-O-(dimethoxytrityl) guanosine gave the desired products 5a–d in excellent yields.
Coupling of products 5a–d with unprotected thymidine resulted in formation of 3',5'-linked dinucleosides 6a–d selectively, and the dimer 7 from reaction with secondary hydroxyl group of thymidine was not observed (eq 3). Subsequent silylation and coupling with another molecule of thymidine gave 3,5- linked trinucleoside 8 in 76% yield (eq 4). A tetrathymidylate oligomer was prepared by 3'-O-silylation of 8 followed by coupling with thymidine. Although no self-condensation was observed, only 30% of the product 9 was obtained after purification by preparative HPLC.

Preparation

conveniently prepared by the slow addition of 2 equiv of trifluoromethanesulfonic acid to a stirring mixture of chlorodiisopropylsilane, followed by direct distillation of the product from the reaction flask to yield the product as a pale yellow oil.

storage

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) should be stored in the refrigerator under an inert atmosphere of argon or nitrogen. Special care should be used when handling since diisopropysilyl bis(trifluoromethanesulfonate) has been classified as a corrosive.

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) Suppliers

China 39 India 1 Switzerland 1 United Kingdom 2 United States 5 Global 48

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16075
Advantage: 64

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Shanghai Gileader Advanced Material Technology Co.,Ltd

Tel: 18516111942
Email: 823898732@qq.com
Country: China
ProdList: 1328
Advantage: 56

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai Enchem Industry Co., Ltd.

Tel: 15021317485
Fax: 021-58109752
Country: China
ProdList: 1403
Advantage: 58

Shanghai Zhuang Ming New Material Technology Co., Ltd.

Tel: 17312398916 051386936896 15216715905
Fax: 051386936896
Email: sales@zhuangming.net
Country: China
ProdList: 1271
Advantage: 58

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6468
Advantage: 55

Xuzhou ZhuoYun New Material Technology Co., Ltd.

Tel: 0516-0516 13776763863
Fax: -
Email: zhangqinli.ok@163.com
Country: China
ProdList: 1265
Advantage: 58

Suzhou Siso new material Co.,Ltd.

Tel: 0512-65402974 18550909935;
Fax: 0512-67544899
Email: siso03@126.com
Country: China
ProdList: 1913
Advantage: 58

Henan Alfachem Co.,Ltd.

Tel: 0371-55051623 18137891487
Fax: QQ：2853979817
Email: 2853979817@qq.com
Country: China
ProdList: 9988
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

HUNAN CHEMFISH SCIENTIFIC CO.,LTD

Tel: +86-0731-85567275 13298656710
Fax: QQ:3554193828
Email: sales05@chemfish.com
Country: China
ProdList: 7448
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Zhuangming New Material Technology Jiangsu Co., Ltd.

Tel: 021-0513-86936896 18116363706
Email: sales@zhuangming.net
Country: China
ProdList: 583
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Hubei kefule Material Technology Co., Ltd

Tel: 027-84459282 13720265353
Email: zhou@cfmats.com
Country: China
ProdList: 881
Advantage: 58

Hubei Co-Formula Material Tech Co., Ltd.

Tel: +86-27-84459282
Fax: +86-27-84459282
Email: sales@cfmats.com
Country: CHINA
ProdList: 882
Advantage: 58

Shanghai Qiming New Material Co. LTD

Tel: 021-36010885 13661599081
Fax: 021-66167180
Email: sale@qmsilicon.com
Country: China
ProdList: 1474
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shandong Territorial sea Biological Technology Co., LTD

Tel: 15092083467
Email: 18660263263@163.com
Country: China
ProdList: 2810
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054;
Email: trendseenbio@gmail.com
Country: China
ProdList: 9069
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-025-66113011 18626450290
Email: cb5@aikonchem.com
Country: China
ProdList: 10358
Advantage: 58

Anyang Hongmeng New Materials Co., Ltd

Tel: 0372-19588588067 19588588067
Email: 19588588067@163.com
Country: China
ProdList: 2393
Advantage: 58

Tianjin Rongshen Chemical Co., Ltd

Tel: 18317763565; 18317763565
Email: 18317763565@163.com
Country: China
ProdList: 9516
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Yulin Runtianchang Chemical Co., Ltd

Tel: 15890142075
Email: 3555133855@qq.com
Country: China
ProdList: 9853
Advantage: 58

Shanghai Daken Advanced Materials Co.,Ltd

Tel: +86-2158073036
Email: info@dakenam.com
Country: China
ProdList: 13599
Advantage: 58

DAYANG CHEM (HANGZHOU) CO.,LTD

Tel: +86-88938639 +86-17705817739
Email: info@dycnchem.com
Country: China
ProdList: 53899
Advantage: 58

Shanghai Zhuangming Biopharma Co., Ltd.

Tel
Email: inquiry@zmsilane.com
Country: China
ProdList: 716
Advantage: 58

Junwee Chemical co., Ltd.

Tel: +86-571-85808636 +86-13958122542
Email: sales@junweechem.com
Country: China
ProdList: 823
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054
Email: trendseenbio@gmail.com
Country: China
ProdList: 11681
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Guangzhou WeiBo Chemical Co., Ltd.

Tel: --
Fax: --
Email: weibochem@163.com
Country: China
ProdList: 6187
Advantage: 67

More

Less

View Lastest Price from DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) manufacturers

Career Henan Chemical Co

Product: diisopropylbis(trifluoromethanesulfonyl)silane 85272-30-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98%
Supply Ability: g/kg/ton
Release date: 2020-01-08

85272-30-6, DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)Related Search:

RUETASOLV BP 4201 (DIISOPROPYLBIPHENYL MIXTURE OF ISOMERES) SPECIALITY CHEMICALS Trifluoromethane DIMETHYLBIS(TRIFLUOROMETHYLSULFONYLOXY)SILANE DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) DI-TERT-BUTYLSILYL BIS(TRIFLUOROMETHANESULFONATE) DIISOPROPYLSILANE

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)

TRIFLUOROMETHANESULFONIC ACID DIISOPROPYLSILYLENE ESTER

DIISOPROPYLSILYL BIS(TRIFLUOROMETHANE-SU LFONATE), TECH.

diisopropylbis(trifluoromethanesulfonyl)silane

Bis(trifluoromethanesulfonic acid)diisopropylsilanediyl ester

Diisopropylsilylenebis(trifluoromethanesulfonate)

Methanesulfonic acid, trifluoro-, bis(1-methylethyl)silylene ester

Methanesulfonic acid, 1,1,1-trifluoro-, bis(1-methylethyl)[[(trifluoromethyl)sulfonyl]oxy]silyl ester

DK412

Bis(1-methylethyl)[[(trifluoromethyl)sulfonyl]oxy]silyl triflate

Diisopropylsilanediyl bis(trifluoromethanesulfonate)

85272-30-6

C8H14F6O6S2Si

CF3SO32SiCHCH322

Protection and Derivatization

Protecting and Derivatizing Reagents

Silicon-Based

Synthetic Reagents