ChemicalBook > CAS DataBase List > Methyl (R)-(+)-lactate

Methyl (R)-(+)-lactate

Product Name
Methyl (R)-(+)-lactate
CAS No.
17392-83-5
Chemical Name
Methyl (R)-(+)-lactate
Synonyms
Methyl (R)-2-Hydroxypropanoate;METHYL-(R)-LACTATE;D-LACTIC ACID METHYL ESTER;D-Methyl Lactate;DLAM;D- METHYL D-LACTATE;Methyl-(R)-lactat;METHYL D-(+)-LACTATE;(+)-Methyl D-lactate
CBNumber
CB5694817
Molecular Formula
C4H8O3
Formula Weight
104.1
MOL File
17392-83-5.mol
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Methyl (R)-(+)-lactate Property

Boiling point:
144-145 °C(lit.)
alpha 
8.5 º (c=neat)
Density 
1.09 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.413(lit.)
Flash point:
121 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Liquid
pka
13.07±0.20(Predicted)
color 
Clear colorless
optical activity
[α]21/D +8.4°, neat
Water Solubility 
miscible, hydrolyses
Merck 
14,6094
InChIKey
LPEKGGXMPWTOCB-GSVOUGTGSA-N
LogP
-0.719 (est)
CAS DataBase Reference
17392-83-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
10-36/37
Safety Statements 
16-24-24/25
RIDADR 
UN 3272 3/PG 3
WGK Germany 
1
HazardClass 
3
PackingGroup 
III
HS Code 
29181100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
277762
Product name
(+)-Methyl D-lactate
Purity
98%, optical purity ee: 96% (GLC)
Packaging
5g
Price
$126.04
Updated
2025/07/31
TCI Chemical
Product number
L0136
Product name
Methyl D-(+)-Lactate
Purity
>98.0%(GC)
Packaging
5g
Price
$59
Updated
2025/07/31
TCI Chemical
Product number
L0136
Product name
Methyl D-(+)-Lactate
Purity
>98.0%(GC)
Packaging
25g
Price
$185
Updated
2025/07/31
Usbiological
Product number
281843
Product name
D-Methyl lactate
Packaging
50g
Price
$322
Updated
2021/12/16
TRC
Product number
M315230
Product name
Methyl D-(+)-Lactate
Packaging
100g
Price
$625
Updated
2021/12/16
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Methyl (R)-(+)-lactate Chemical Properties,Usage,Production

Chemical Properties

Colorless to light yellow liqui

Uses

(+)-Methyl D-lactate can be used as a starting material in the asymmetric preparation of:

  • Neomethymycin, a macrolide which contains 12-membered macrolactone that is used as a potent biological agent.
  • PM-toxin A.

It can also be used as a chiral pool along with D-(-)-tartaric acid in the stereoselective total synthesis of separacenes A and B via Trost-Rychnovsky alkyne rearrangement, Horner-Wadsworth-Emmons olefination as well as Corey-Bakshi-Shibata reaction.

Definition

ChEBI: A methyl lactate that has R configuration.

General Description

This compound has benign qualities and is biodegradable, water miscible, and functions as a versatile solvent for CA membrane preparation. This is also used as an intermediate for the production of other chemicals, polymers, and derivatives. Thus this product has been enhanced for Safer solvents and auxiliaries.

Synthesis

547-64-8

79-33-4

17392-83-5

The general procedure for the synthesis of L-lactic acid and D-lactic acid methyl ester from methyl lactate was as follows: in a standard 500-μL hydrolysis reaction system, 140 μg of purified esterase PHE14, 50 mmol/L of racemic methyl lactate as substrate, and 50 mmol/L of phosphate buffer (pH 7.5) were added. The reaction system was incubated at 37°C for 1 hour. Upon completion of the reaction, the reaction samples were extracted using an equal volume of ethyl acetate, and the organic phase was subsequently analyzed to assess the enzymatic disassembly of (±)-lactic acid methyl ester.

References

[1] Chinese Journal of Catalysis, 2016, vol. 37, # 8, p. 1396 - 1402
[2] Green Chemistry, 2013, vol. 15, # 10, p. 2817 - 2824

Methyl (R)-(+)-lactate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyl (R)-(+)-lactate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Methyl (R)-(+)-lactate 17392-83-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
5000kg/month
Release date
2021-10-13
Hebei Chuanghai Biotechnology Co., Ltd
Product
Methyl (R)-(+)-lactate 17392-83-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Zhuozhou Wenxi import and Export Co., Ltd
Product
(+)-Methyl D-lactate 98%, optical purity ee: 96% (GLC) 17392-83-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

17392-83-5, Methyl (R)-(+)-lactateRelated Search:

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  • Methyl-D-lactate >=99.0%,Chiral grade
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  • D-&nbsp
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  • (+)-Methyl D-lactate 98%, optical purity ee: 96% (GLC)
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  • methyl dextro-lactate
  • METHYL (R)-(+)-LACTATE
  • METHYL-(R)-LACTATE
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  • DLAM
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  • (R)-(+)-METHYL LACTATE
  • Methyl (R)-(+)-lactate,98%
  • D-Lactic acid methyl ester, Methyl (R)-(+)-lactate
  • Methyl-(R)-lactat
  • (R)-2-hydroxy-propanoic acid methyl ester
  • (+)-Methyl D-lactate, 98%, (96% ee/GLC)
  • D-(+)-LACTIC ACID METHYL ESTER 98+%
  • Propanoic acid, 2-hydroxy-, methyl ester, (2R)-
  • (2R)-2-Hydroxypropionic acid methyl ester
  • [R,(+)]-2-Hydroxypropionic acid methyl ester
  • D-Methyl Lactate
  • chiral grade methyl lactate
  • (+)-METHYLD-LACTATE/Methyl(R)-(+)-lactate
  • MethylD-(+)-Lactate&gt
  • R-Hydroxy propionic acdi methyl ester
  • (+)-Methyl D-lactate
  • Posaconazole Impurity 151
  • (+)-Methyl <sc>D</sc>-lactate
  • D-(+)-Methyl Lactate 99% Optical purity:99%
  • 17392-83-5
  • CH3CHOHCO2CH3
  • ALCOHOL
  • Asymmetric Synthesis
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  • Organic Building Blocks
  • Esters
  • Building Blocks for Liquid Crystals
  • Chiral Compounds (Building Blocks for Liquid Crystals)
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