ChemicalBook > CAS DataBase List > Ketanserin

Ketanserin

Product Name
Ketanserin
CAS No.
74050-98-9
Chemical Name
Ketanserin
Synonyms
RHS;Ket;p73L;p73H;OFC8;EEC3;SHFM4;p53CP;TP53L;TP73L
CBNumber
CB5704758
Molecular Formula
C22H22FN3O3
Formula Weight
395.43
MOL File
74050-98-9.mol
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Ketanserin Property

Melting point:
227-235°C
Density 
1.280±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMF: 10 mg/mL, clear, colorless
form 
Solid
pka
7.5(at 25℃)
color 
White to Off-White
Merck 
14,5296
CAS DataBase Reference
74050-98-9(CAS DataBase Reference)
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Safety

WGK Germany 
3
RTECS 
VA1411190
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

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N-Bromosuccinimide Price

TCI Chemical
Product number
K0051
Product name
Ketanserin
Purity
>98.0%(HPLC)(T)
Packaging
200mg
Price
$62
Updated
2024/03/01
TCI Chemical
Product number
K0051
Product name
Ketanserin
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$186
Updated
2024/03/01
TRC
Product number
K165450
Product name
Ketanserin
Packaging
50mg
Price
$50
Updated
2021/12/16
TRC
Product number
K165450
Product name
Ketanserin
Packaging
250mg
Price
$135
Updated
2021/12/16
ApexBio Technology
Product number
B2248
Product name
Ketanserin
Packaging
50mg
Price
$40
Updated
2021/12/16
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Ketanserin Chemical Properties,Usage,Production

Description

Ketanserin is an antihypertensive agent with antagonist properties at both the serotonin-S2 and α1-adrenergic receptors. Its mechanism of action, while still controversial, may involve interactions at both of these loci.

Chemical Properties

Off-White Solid

Originator

Janssen (Belgium)

Uses

An antihypertensive, with affinity for multiple GPCR receptors.

Uses

receptor antagonist

Definition

ChEBI: A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

brand name

SEREFREX

Purification Methods

It has been purified by recrystallisation from 4-methyl-3-pentanone [Peeters et al. Cryst Structure Commun 11 375 1982, Kacprowicz et al. J Chromatogr 272 417 1983, Davies et al. J Chromatogr 275 232 1983]. It is an antihypertensive.

Ketanserin Preparation Products And Raw materials

Raw materials

4-(4-Fluorobenzoyl)piperidine 2-Pentanone

Preparation Products

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Ketanserin Suppliers

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View Lastest Price from Ketanserin manufacturers

Sinoway Industrial co., ltd.
Product
Ketanserin 74050-98-9
Price
US $0.00/Kg/Bag
Min. Order
2Kg/Bag
Purity
99% up / EP
Supply Ability
20 tons
Release date
2021-07-21
Hebei Duling International Trade Co. LTD
Product
Ketanserin 74050-98-9
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2022-10-17
Hebei Yanxi Chemical Co., Ltd.
Product
Ketanserin 74050-98-9
Price
US $50.00-10.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-15

74050-98-9, KetanserinRelated Search:

Hydroxyurea Everolimus Vincristine sulfate RS-127445 ABT 737 A 769662 Barasertib (AZD1152-HQPA) Quinazoline Ketanserin/Ritanserin/Sufrexal/Serefrex KETANSERIN TARTRATE,KETANSERIN TARTRATE SALT,KETANSERIN TARTRATE (R 41468) (SELECTIVE 5-HT2/5-HT1C SEROTONI 7-azidoketanserin KETANSERIN HCL, [ETHYLENE-3H]-,KETANSERIN HYDROCHLORIDE, [ETHYLENE-3H]- Ketanserin 7-aminoketanserin

  • Ketanserin, 99%, a specific 5-HT2A serotonin receptor antagonist
  • B(p51A)
  • B(p51B)
  • EEC3
  • OFC8
  • p53CP
  • p63, GST tagged human
  • p73H
  • p73L
  • RHS
  • SHFM4
  • TP53CP
  • TP53L
  • TP73L
  • 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1h,3h]-quinazolinedione
  • KETANSERIN
  • 3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione
  • 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2，4-(IH，3H)-quinazolinedione
  • Ketanserin (Vulketan Gel)|
  • Ketanserin(R 41 468)
  • Ket
  • Ketensin
  • Perketan
  • R-49945
  • Serefrex
  • Serepress
  • Sufrexal
  • Taseron
  • 2,4(1H,3H)-Quinazolinedione, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-
  • 3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione
  • 3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-2,4(1H,3H)-quinazolinedione
  • 3-[2-[4-(4-Fluorobenzoyl)piperidino]ethyl]-2,4(1H,3H)-quinazolinedione
  • Ketanserine
  • Ketanserin&gt
  • Ketanserinum
  • Ketanserin USP/EP/BP
  • Ketanserine Base
  • 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-1,2,3, 4-tetrahydroquinazoline-2,4-dione
  • TIANFU CHEM----Ketanserin
  • Ketanserin,3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione
  • 3-[2-[4-(4-Fluorobenzoyl)-1-piperidyl]ethyl]quinazoline-2,4(1H,3H)-dione
  • 74050-98-9
  • C22H22FN3O3
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Other APIs
  • ketone