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2-Bromophenethylamine

Product Name
2-Bromophenethylamine
CAS No.
65185-58-2
Chemical Name
2-Bromophenethylamine
Synonyms
RARECHEM AL BW 0201;2-BROMOPHENETHYLAMINE;2-Bromophenethanamine;2-bromophenylethyl amine;2-BroMophenethylaMine 97%;2-BroMo-benzeneethanaMine;2-Bromophenethylamine,99%;2-(2-bromophenyl)ethanamine;BENZENEETHANAMINE, 2-BROMO-;1-Amino-(2-bromophenyl)ethane
CBNumber
CB5716078
Molecular Formula
C8H10BrN
Formula Weight
200.08
MOL File
65185-58-2.mol
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2-Bromophenethylamine Property

Boiling point:
253 °C(lit.)
Density 
1.396 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.5770(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
pka
9.52±0.10(Predicted)
color 
Clear colorless to slightly yellow
Sensitive 
Air Sensitive
InChI
1S/C8H10BrN/c9-8-4-2-1-3-7(8)5-6-10/h1-4H,5-6,10H2
InChIKey
ITRNQMJXZUWZQL-UHFFFAOYSA-N
SMILES
NCCc1ccccc1Br
CAS DataBase Reference
65185-58-2(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-27-36/37/39-45
RIDADR 
UN 2735 8/PG 2
WGK Germany 
3
HazardClass 
8
PackingGroup 
HS Code 
29214990
Storage Class
8A - Combustible corrosive hazardous materials
Hazard Classifications
Skin Corr. 1B
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
534099
Product name
2-Bromophenethylamine
Purity
97%
Packaging
10g
Price
$267
Updated
2026/03/19
Sigma-Aldrich
Product number
534099
Product name
2-Bromophenethylamine
Purity
97%
Packaging
5g
Price
$147
Updated
2023/06/20
TCI Chemical
Product number
B3938
Product name
2-(2-Bromophenyl)ethylamine
Purity
>98.0%(T)
Packaging
5g
Price
$127
Updated
2026/03/19
TCI Chemical
Product number
B3938
Product name
2-(2-Bromophenyl)ethylamine
Purity
>98.0%(T)
Packaging
25g
Price
$377
Updated
2026/03/19
TRC
Product number
B683640
Product name
2-Bromophenylethylamine
Packaging
25g
Price
$350
Updated
2021/12/16
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2-Bromophenethylamine Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

2-(2-Bromophenyl)ethylamine is used as a pharmaceutical intermediate.

General Description

May darken in storage

Synthesis

19472-74-3

65185-58-2

The general procedure for the synthesis of o-bromophenethylamine from o-bromobenzyl cyanide was as follows: 1 M borane-tetrahydrofuran complex (BH3-THF, 200 mL, 0.2 mol) was slowly added dropwise to a solution of 2-bromobenzyl cyanide (20.0 g, 0.1 mol) in tetrahydrofuran (THF, 100 mL) at 0 °C for 30 min. Subsequently, the reaction mixture was heated to reflux for 24 hours. Upon completion of the reaction, the reaction was quenched with methanol (MeOH, 50 mL) and 6 M hydrochloric acid (HCl, 50 mL) at 0 °C, and then the mixture was heated and refluxed again for 4 hours. The reaction solution was concentrated under reduced pressure and the residue was diluted with distilled water (H2O, 300 mL) and washed with ethyl acetate (EA, 75 mL × 2). The aqueous layer was neutralized with 15% sodium hydroxide (NaOH) solution and then extracted with ethyl acetate (EA, 75 mL × 2). The organic layers were combined, dried with anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to afford the target product o-bromophenethylamine (2a) as a yellow oil (17.4 g, 85.2% yield). High-resolution mass spectrometry (HRMS) calculated value C8H11NBr [M + H]+ 200.0069, measured value 200.0068. nuclear magnetic resonance hydrogen spectrum (1H NMR, 500 MHz, CDCl3) δ 7.58 (d, J = 8.0 Hz, 1H), 7.35-7.31 (m, 2H), 7.15 (t, J = 7.0 Hz, 1H). 2.79 (m, 4H), 1.18 (m, 2H). Nuclear magnetic resonance carbon spectrum (13C NMR, 125 MHz, DMSO-d6) δ 139.8,132.9,131.6,128.6,128.2,124.3,42.4,40.3.

References

[1] Journal of Organic Chemistry, 2008, vol. 73, # 24, p. 9627 - 9632
[2] Patent: US2002/198251, 2002, A1
[3] Tetrahedron, 1996, vol. 52, # 21, p. 7525 - 7546
[4] Tetrahedron, 1998, vol. 54, # 25, p. 7121 - 7126
[5] ChemCatChem, 2014, vol. 6, # 2, p. 538 - 546

2-Bromophenethylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromophenethylamine Suppliers

Shanghai Linghua Pharmaceutical Technology Co., Ltd.
Tel
15000172640
Email
linghua@lingpharm.cn
Country
China
ProdList
29
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
ITIC MEDCHEM(SUZHOU) CO.,LTD.
Tel
0512-68323967 18015559028
Fax
+86-512-69200360
Email
sales@iticmedchem.com
Country
China
ProdList
517
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44802
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
13552068683 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
11780
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9254
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
marketing@accelachem.com
Country
China
ProdList
10977
Advantage
64
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View Lastest Price from 2-Bromophenethylamine manufacturers

LY Global chemicals co.,ltd .
Product
2-Bromophenethylamine 65185-58-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98.0%
Supply Ability
10000kg
Release date
2023-03-30
Career Henan Chemical Co
Product
2-(2-Bromophenyl)ethanamine 65185-58-2
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-02-03

65185-58-2, 2-BromophenethylamineRelated Search:


  • RARECHEM AL BW 0201
  • BENZENEETHANAMINE, 2-BROMO-
  • 2-BROMOPHENETHYLAMINE
  • 2-(2-bromophenyl)ethanamine
  • 2-bromophenylethyl amine
  • 2-Bromophenethylamine,99%
  • 2-BroMo-benzeneethanaMine
  • 2-BroMophenethylaMine 97%
  • 2-(2-BroMophenyl)ethanaMine, 98%+
  • 2-(2-bromophenyl)ethylammonium
  • 2-(2-Bromophenyl)ethylamine &gt
  • 1-Amino-(2-bromophenyl)ethane
  • 2-Bromophenethanamine
  • 65185-58-2
  • Nitrogen Compounds
  • Organic Building Blocks
  • C8
  • Amines
  • Building Blocks
  • AMINE
  • Phenyls & Phenyl-Het
  • Amines
  • C8
  • Nitrogen Compounds
  • Halides
  • Phenyls & Phenyl-Het