2-Nitroethanol Property

Melting point:

-80 °C (lit.)

Boiling point:

194 °C/765 mmHg (lit.)

Density 

1.27 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.445(lit.)

Flash point:

>230 °F

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

Chloroform, DMSO, Methanol (Sparingly)

form 

Liquid

pka

8.42±0.29(Predicted)

color 

Clear yellow

BRN 

1633753

CAS DataBase Reference

625-48-9(CAS DataBase Reference)

NIST Chemistry Reference

Ethanol, 2-nitro-(625-48-9)

EPA Substance Registry System

2-Nitroethanol (625-48-9)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

KL9370000

F 

3

HS Code 

29055910

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-Nitroethanol Chemical Properties,Usage,Production

Chemical Properties

Clear yellow liquid

Uses

2-Nitroethanol is an aliphatic β-nitro alcohol used as an in vivo therapeutic corneoscleral crosslinking agents with higher order nitroalcohol. It also functions as a crosslinking reagent for scieral tissue cross-linking of the eye cornea for treating keratoconus and post-surgical keratectasia.

General Description

Mobile dark brown-red liquid with a pungent odor.

Air & Water Reactions

Hygroscopic. Insoluble in water.

Reactivity Profile

2-Nitroethanol is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides. 2-Nitroethanol has exploded under vacuum distillation(attributed to the presence of peroxides or alkali).

Fire Hazard

2-Nitroethanol is probably combustible.