TELMISARTAN-D3

Product Name: TELMISARTAN-D3
CAS No.: 1189889-44-8
Chemical Name: TELMISARTAN-D3
Synonyms: Pritor-d3;BIBR 277-d3;Micardis-d3;BIBR 277SE-d3;TELMISARTAN-D3;D3-Telmisartan;Telmisartan-d3 in methanol;4'-[(1,4'-DiMethyl-2'-propyl[2,6'-bi-H-benziMidazol]-1'-yl)Methyl][1,1'-biphenyl]-2-carboxylic Acid-d3;4'-[[4-Methyl-6-(1-Methyl-2-benziMidazolyl)-2-propyl-1-benziMidazolyl] Methyl]-2-biphenylcarboxylic Acid-d3;4'-({4-methyl-6-[1-(2H?)methyl-1H-1,3-benzodiazol-2-yl]-2-propyl-1H-1,3-benzodiazol-1-yl}methyl)-[1,1'-biphenyl]-2-carboxylic acid
CBNumber: CB5730269
Molecular Formula: C33H27D3N4O2
Formula Weight: 517.64
MOL File: Mol file

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TELMISARTAN-D3 Property

Melting point:: 262-265°C
storage temp.: -20°C Freezer, Under Inert Atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
color: White to Beige

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22568
Product name: Telmisartan-d3
Purity: ≥99% deuterated forms (d1-d3)
Packaging: 500μg
Price: $178
Updated: 2024/03/01

Cayman Chemical

Product number: 22568
Product name: Telmisartan-d3
Purity: ≥99% deuterated forms (d1-d3)
Packaging: 1mg
Price: $336
Updated: 2024/03/01

TRC

Product number: T017002
Product name: Telmisartan-d3
Packaging: 1mg
Price: $175
Updated: 2021/12/16

Usbiological

Product number: T2240-01
Product name: Telmisartan-d3
Packaging: 1mg
Price: $446
Updated: 2021/12/16

AK Scientific

Product number: 5586DF
Product name: Telmisartan-d3
Packaging: 1mg
Price: $472
Updated: 2021/12/16

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TELMISARTAN-D3 Chemical Properties,Usage,Production

Description

Telmisartan-d₃ is intended for use as an internal standard for the quantification of telmisartan by GC- or LC-MS. Telmisartan is a nonpeptide angiotensin (AT) II receptor antagonist which selectively and insurmountably inhibits the AT II receptor subtype AT₁ (K_i = 3.7 nM). It also acts as a partial agonist of peroxisome proliferator-activated receptor gamma (PPARγ), activating the receptor to 25-30% of that produced by the full agonist rosiglitazone (; EC₅₀ = 4.5 μM). Through these actions, telmisartan potently reduces blood pressure in various animal models of hypertension, diminishing cardiac hypertrophy, cardiovascular and renal risk, and glomerulosclerosis.

Chemical Properties

Off-White Crystalline Solid

Uses

Labelled Telmisartan, an angiotensin II receptor antagonist

Uses

TelMisartan-d3 can be intended for use as an internal standard for the quantification of Telmisartan by GC- or LC-mass spectrometry.

Uses

TelMisartan-d3 is an angiotensin II receptor antagonist.

References

[1] W. WIENEN. Pharmacological characterization of the novel nonpeptide angiotensin II receptor antagonist, BIBR 277[J]. British Journal of Pharmacology, 1993, 110 1: 245-252. DOI: 10.1111/j.1476-5381.1993.tb13800.x
[2] STEPHEN C BENSON. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.[J]. Hypertension, 2004, 43 5: 993-1002. DOI: 10.1161/01.hyp.0000123072.34629.57
[3] ARONOW W S. Telmisartan[J]. Drugs, 2012, 56 1: 1045. DOI: 10.2165/00003495-199856060-00009
[4] JUGDUTT B I. Clinical effectiveness of telmisartan alone or in combination therapy for controlling blood pressure and vascular risk in the elderly.[J]. Clinical Interventions in Aging, 2010, 5: 403-416. DOI: 10.2147/cia.s6709
[5] ROLAND E SCHMIEDER Matthew R W George Bakris. Telmisartan in incipient and overt diabetic renal disease.[J]. Journal of Nephrology, 2011, 24 3: 263-273. DOI: 10.5301/jn.2011.6416

TELMISARTAN-D3 Preparation Products And Raw materials

Raw materials

Preparation Products

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TELMISARTAN-D3 Suppliers

Canada 3 CHINA 49 India 3 United States 5 Global 60

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Cato Research Chemicals Inc.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Shenzhen SUNGENING Bio-Medical Co., Ltd.

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Chengdu Novel Biomedical Co., Ltd.

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1189889-44-8, TELMISARTAN-D3Related Search:

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate 6-Des(1-Methyl-2-benziMidazolyl)-6-carboxy TelMisartan 2-n-Propyl-4-methyl-6-(1-methylbenzimidazole-2-yl)benzimidazole Telmisartan Related Compound B (15 mg) (4'-[(1,7'-dimethyl-2'-propyl-1H,1'H-2,5'-bibenzo[d]imidazol-1'-yl)methyl]biphenyl-2-carboxylic acid) propyl[2,6'-bi-1H-benzimidazol]-1'-yl]methyl]- TelMisartan AMide Telmisartan tert-Butyl Ester TelMisartan-13CD3 Telmisartan

TELMISARTAN-D3

4'-[(1,4'-DiMethyl-2'-propyl[2,6'-bi-H-benziMidazol]-1'-yl)Methyl][1,1'-biphenyl]-2-carboxylic Acid-d3

4'-[[4-Methyl-6-(1-Methyl-2-benziMidazolyl)-2-propyl-1-benziMidazolyl] Methyl]-2-biphenylcarboxylic Acid-d3

BIBR 277-d3

BIBR 277SE-d3

Micardis-d3

Pritor-d3

Telmisartan D3Q: What is Telmisartan D3 Q: What is the CAS Number of Telmisartan D3 Q: What is the storage condition of Telmisartan D3 Q: What are the applications of Telmisartan D3

4'-({4-methyl-6-[1-(2H?)methyl-1H-1,3-benzodiazol-2-yl]-2-propyl-1H-1,3-benzodiazol-1-yl}methyl)-[1,1'-biphenyl]-2-carboxylic acid

Telmisartan-d3 in methanol

D3-Telmisartan

1189889-44-8

C33H27D3N4O2

Intermediates & Fine Chemicals

Metabolites

Pharmaceuticals

Various Metabolites and Impurities

Aromatics

Heterocycles

Isotope Labelled Compounds