ChemicalBook > CAS DataBase List > (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine

Product Name
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
CAS No.
105812-81-5
Chemical Name
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
Synonyms
PAROXOL;(-)-Paroxol;[(3S,4S)-4-(4-fL;Compound Fr13375;Paroxetine Impurity 18;Paroxetine impurities783;(3S,4R)-N-Methyl Paroxol;(3S,4R)-4-(4-Fluorophenyl)-3-h;[(3S,4R)-4-(4-Fluorophenyl)-1-methy;Paroxetine (3S,4R)-N-Methyl Paroxol Impurity
CBNumber
CB5737006
Molecular Formula
C13H18FNO
Formula Weight
223.29
MOL File
105812-81-5.mol
More
Less

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Property

Melting point:
97-101 °C
alpha 
-38 º (c=1, MeOH)
Boiling point:
300.3±42.0 °C(Predicted)
Density 
1.092±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
14.93±0.10(Predicted)
color 
White to Almost white
InChI
InChI=1S/C13H18FNO/c1-15-7-6-13(11(8-15)9-16)10-2-4-12(14)5-3-10/h2-5,11,13,16H,6-9H2,1H3/t11-,13-/m0/s1
InChIKey
CXRHUYYZISIIMT-AAEUAGOBSA-N
SMILES
N1(C)CC[C@@H](C2=CC=C(F)C=C2)[C@H](CO)C1
CAS DataBase Reference
105812-81-5(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
N-Xn,N,Xn
Risk Statements 
51/53-41-22
Safety Statements 
61-39-26-22-37/39-24
RIDADR 
UN3077
HazardClass 
9
PackingGroup 
III
HS Code 
29333999
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

H401Toxic to aquatic life

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
F0878
Product name
(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$70
Updated
2024/03/01
TCI Chemical
Product number
F0878
Product name
(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$259
Updated
2024/03/01
Alfa Aesar
Product number
H28137
Product name
(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol, 98%
Packaging
5g
Price
$57.6
Updated
2021/12/16
Alfa Aesar
Product number
H28137
Product name
(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol, 98%
Packaging
25g
Price
$170
Updated
2021/12/16
TRC
Product number
P205800
Product name
Paroxol
Packaging
5g
Price
$110
Updated
2021/12/16
More
Less

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

An intermediate in the synthesis of Paroxetine, a selective serotonin reuptake inhibitor.

Uses

An intermediate in the synthesis of Paroxetine (P205750), a selective serotonin reuptake inhibitor.

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Suppliers

Americas 1 Belgium 2 Canada 1 China 241 Europe 2 Germany 5 India 34 Indonesia 1 Japan 1 United Kingdom 8 United States 34 Global 330
Hangzhou Benoy Chemical Co., Ltd.
Tel
17342059697
Fax
QQ:2710089141
Email
sales@benoychem.com
Country
China
ProdList
391
Advantage
58
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4772
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19186
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8835
Advantage
52
Shanghai Feibo Chemical Technology Co., Ltd
Tel
021-58955608,2250286 15921236618
Email
blinkzeng@gmail.com
Country
China
ProdList
522
Advantage
62
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
6791
Advantage
65
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
Runpharm Technology Limited
Tel
18171398856 2968382473
Fax
0086-21-50758330
Email
service@runpharm.com
Country
China
ProdList
716
Advantage
55
Doly Chemical CO.,LTD.
Tel
021-34716221 15800796336
Fax
+86-21-31329566
Email
sales@dolypharm.com
Country
China
ProdList
295
Advantage
55
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4674
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4924
Advantage
55
ALPENGLOW CHEMICAL INDUSTRIAL CO., LTD
Tel
086-0531-86986713
Fax
086-0531-86980810
Email
aplgroup@163.com
Country
China
ProdList
96
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9346
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Shouguang Jiasheng Chemical Co., Ltd.
Tel
0536-7971999 18232719690
Fax
0536-7971999
Email
sgjiasheng@hotmail.com
Country
China
ProdList
347
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4943
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10274
Advantage
55
Shanghai QianJin Chemical Technology Co., Ltd
Tel
021-20900665 17321230821
Fax
021-20900665
Email
2986274987@qq.com
Country
China
ProdList
874
Advantage
55
Shanghai YouPeng Chemical Co. Ltd.
Tel
021-69005955 13701776567
Fax
021-69005775
Email
youpengchem@163.com
Country
China
ProdList
4295
Advantage
56
Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
ProdList
4321
Advantage
58
Shanghai Kaisai Chemical Co., Ltd
Tel
021-33516722 13701817765
Fax
021-33516776
Email
kaisaichem@163.com
Country
China
ProdList
4743
Advantage
58
Shanghai Rolead Chemical Technology Co., Ltd.
Tel
021-69992220 13701886816
Fax
021-69992237
Email
roleadchem@163.com
Country
China
ProdList
4750
Advantage
50
Shanghai Kangtuo Chemical Co., Ltd.
Tel
021-69185552 13701777608
Fax
021-69186006
Email
kangtuochem@163.com
Country
China
ProdList
4360
Advantage
55
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7892
Advantage
55
Hubei Kangbaotai Finechem Co., Ltd.
Tel
+86 (27) 8778653
Fax
+86 (27) 8773-8652
Email
13720228325@163.com
Country
China
ProdList
337
Advantage
58
Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6464
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Chengdu DingDang Pharmaceutical Co., Ltd.
Tel
028-86040038 13980902949;
Fax
028-85149890
Email
market@dingdangchem.com
Country
China
ProdList
1850
Advantage
55
More
Less

View Lastest Price from (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine manufacturers

Hangzhou ICH Biofarm Co., Ltd
Product
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine 105812-81-5
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99.0%min
Supply Ability
200kg
Release date
2023-06-12
Shanghai CRM New Material Technology Co., LTD
Product
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine 105812-81-5
Price
US $10.00-15.00/g
Min. Order
10g
Purity
99%
Supply Ability
2546245
Release date
2022-09-20
Career Henan Chemical Co
Product
(-)-Trans-1-methyl-3-hydroxymethyl-4-(4-fluorophenyl)piperdine 105812-81-5
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100
Release date
2018-07-26

105812-81-5, (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidineRelated Search:

2,2,6,6-Tetramethyl-4-piperidinol DROPERIDOL Haloperidol 1,2,2,6,6-Pentamethyl-4-piperidinol Tris(hydroxymethyl)nitromethane Triacetonediamine 4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine paroxetine Mesylate Paroxetine Impurity 5 Paroxetine Related Impurity 7 3S4R 3S,4R-4-[phenyl-1-methylpiperidinyl] methanol 1,3-Benzodioxol-4-ol Paroxetine Impurity 16 PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE) Paroxetine Impurity 17 1,3-Benzodioxole Paroxetine EP Impurity I HCl 3S4R Paroxetine

  • (-)-TRANS-4-(4-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE
  • (-)-TRANS-4R-(4-FLUOROPHENYL)-3S-HYDROXYMETHYL-1-METHYLPIPERIDINE
  • TRANS-(-)-4-FLUOROPHENYL-1-METHYL-3-PIPERIDINE METHANOL
  • (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol,98%
  • (3S)-4-(4'-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE
  • (3S,4R)-4-(4'-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE
  • (3S,4R)-4-(4-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE
  • (4R,3S)4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine
  • [(3S,4R)-4-(4-Fluorophenyl)-1- methylpiperidinyl]methanol,99%e.e.
  • Paroxetine Impurity 18
  • (3S,4R)-trans-(-)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
  • (-)Trans-1-N-Methyl-3-Hydroxy Methyl-4-(4-Fluoro Phenyl) Piperidine
  • Paroxetine (3S,4R)-N-Methyl Paroxol Impurity
  • [(3S,4R)-4-(4-fluorophenyl)-1-methyl-3-piperidyl]methanol
  • (4R,3S)-4-(4-FLUOROPHENYL)-3-HYDROXY METHYL-N-METHYL PIPERIDINE
  • (-)-Trans-4R-(4-Fluorophenyl)-3S-hydroxymethyl-N-methylpiperidine
  • (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol, 98%
  • Trans-(-)-4-(4-Fluorophenyl)-1-Methyl-3-Piperidine Methanol
  • PAROXOL
  • 4, (-)trans-4R-(4-fluorophenyl)-3S-hydroxymethyl-1-methylpiperidine
  • 3-Piperidinemethanol,4-(4-fluorophenyl)-1-methyl-,(3S,4R)- 　
  • (4S,3S)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol
  • (3S,4R)-4-(4-Fluorophenyl)-3-h
  • (2S)-1-(4-FLUOROPHENYL)-4-METHYLPIPERAZIN-2-YL]METHANOL
  • ((3S,4S)-4-(4-fluorophenyl)-1-Methylpiperidin-3-yl)Methanol
  • (3S-trans)-4-(4-Fluorophenyl)-1-Methyl-3-piperidineMethanol
  • (4R,3S)-4-(4-Fluorophenyl)-1-Methyl-3-piperidineMethanol
  • (3S,4R)-4-(4'-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine,98%
  • 3S,4R-4-[(4-fluorophenyl)-1-methylpiperi dinyl] methanol
  • (-)-Trans-1-methyl-3-hydroxymethyl-4-(4-fluorophenyl)piperdine
  • Paroxetine IMpurity - (3S,4R)-N-Methyl Paroxol
  • (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol &gt
  • [(3S,4R)-4-(4-Fluorophenyl)-1-methy
  • [(3S,4S)-4-(4-fL
  • (-)Trans-4'-fluorophenyl-3-hydroxymethyl-l-methylpiperidine
  • (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidin...
  • Paroxetine impurities783
  • (3S,4R)-N-Methyl Paroxol
  • (-)TRANS-4R-(4-FLUOROPHENYL)-3S-HYDROXYMETHYL-1-METHYL PIPERIDINE
  • (3S,4R)-3-hydroxymethyl-4-(4'-fluorophenyl)-N-methylpiperidine
  • (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-met
  • Compound Fr13375
  • (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine OR (-) - Alcohol or (-) Carbinol
  • (-)-Paroxol
  • (-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine
  • 105812-81-5
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • chiral
  • (intermediate of paroxetine)
  • bc0001