1,3-Benzodioxole
- Product Name
- 1,3-Benzodioxole
- CAS No.
- 274-09-9
- Chemical Name
- 1,3-Benzodioxole
- Synonyms
- Benzo[d][1,3]dioxole;Benzodioxole;1,2-METHYLENEDIOXYBENZENE;1,2-Methylenedioxybenzene (MDB);1,3-DIOXAINDANE;1,3-BENZODIOXOL;BENZO[1,3]DIOXOLE;1,2-METHYLENDIOXYBENZENE;3,4-METHYLENEDIOXYBENZENE;MDB
- CBNumber
- CB4180652
- Molecular Formula
- C7H6O2
- Formula Weight
- 122.12
- MOL File
- 274-09-9.mol
1,3-Benzodioxole Property
- Melting point:
- -18 °C
- Boiling point:
- 172-173 °C(lit.)
- Density
- 1.064 g/mL at 25 °C(lit.)
- vapor pressure
- 12 mm Hg ( 25 °C)
- refractive index
- n20/D 1.539(lit.)
- Flash point:
- 131 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- 2g/l
- form
- Powder
- color
- Yellow to orange to brown
- Water Solubility
- 0.2 g/100 mL (25 ºC)
- BRN
- 115506
- InChIKey
- FTNJQNQLEGKTGD-UHFFFAOYSA-N
- LogP
- 2.08
- CAS DataBase Reference
- 274-09-9(CAS DataBase Reference)
- NIST Chemistry Reference
- 1,3-Benzodioxole(274-09-9)
- EPA Substance Registry System
- 1,3-Benzodioxole (274-09-9)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/22-22-10-36/37/38-20/21/22-10/22
- Safety Statements
- 23-24/25-36/37/39-26-16-36
- RIDADR
- UN 1993 3/PG 3
- WGK Germany
- 3
- RTECS
- DA5600000
- Hazard Note
- Irritant
- TSCA
- Yes
- HazardClass
- 3
- PackingGroup
- III
- HS Code
- 29329970
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 159166
- Product name
- 1,3-Benzodioxole
- Purity
- 99%
- Packaging
- 50g
- Price
- $65.9
- Updated
- 2025/07/31
- Product number
- M0658
- Product name
- 1,2-Methylenedioxybenzene
- Purity
- >99.0%(GC)
- Packaging
- 25mL
- Price
- $25
- Updated
- 2025/07/31
- Product number
- M0658
- Product name
- 1,2-Methylenedioxybenzene
- Purity
- >99.0%(GC)
- Packaging
- 100mL
- Price
- $64
- Updated
- 2025/07/31
- Product number
- M0658
- Product name
- 1,2-Methylenedioxybenzene
- Purity
- >99.0%(GC)
- Packaging
- 500mL
- Price
- $198
- Updated
- 2025/07/31
- Product number
- B276718
- Product name
- 1,3-Benzodioxole
- Packaging
- 5g
- Price
- $45
- Updated
- 2021/12/16
1,3-Benzodioxole Chemical Properties,Usage,Production
Description
1,3-Benzodioxole, widely found in plant products, has shown potent antioxidant and antibacterial activities. It has recently been reported that 1,3-benzodioxole derivatives possess cytotoxic activity against several human tumor cell lines, including human colon carcinoma cells and multidrug-resistant nasopharyngeal carcinoma cells. No cytotoxic effects were noticed at a concentration of 10-4 M.
Chemical Properties
clear colourless to light yellow liquid. Insoluble in acids.
Uses
1,3-Benzodioxole is useful in gemological stimulant detection. It is also used as a precursor for perfumes, photo initiators, agrochemicals and pharmaceuticals. 1,3-benzodimine is an intermediate for the synthesis of the drugs oxolinic acid, cinoxacin and miloxacin.
Definition
ChEBI: 1,3-benzodioxole is a benzodioxole consisting of a benzene ring substituted by a the methylenedioxy group.
Production Methods
1,3-Benzodioxole is synthesized through the reaction of catechol with dihalomethanes, typically employing a concentrated aqueous alkaline solution in the presence of tetraalkylammonium or phosphonium salts, sometimes in the presence of alkyl iodides. 1,3-Benzodioxole is an important intermediate in organic synthesis, especially for the preparation of alkaloids.
Application
1,3-Benzodioxole belong to methylenedioxyphenyl (MDP) compounds that regulate cytochrome P 450-dependent drug oxidation, which is important in the process of eliminating drugs from the body. a hydrogen abstraction process can take place from the methylene-bridgea carbon of the benzodioxole compound and form a methylenedioxybenzene radical. It is therefore highly likely that 1,3-benzodioxole could serve as hydrogen donor for a CQ-based system initiating the photopolymerization of dental composite resin. In addition, 1,3-benzodioxole is an important organic intermediate (building block) to synthetize substituted methylenedioxybenzene products.
General Description
Supersonic jet fluorescence spectra of 1,3-benzodioxole has been studied. The far-infrared spectrum of the vapour of 1,3-benzodioxole has been reported. The electronic absorption spectra and the laser-induced fluorescence spectra of supersonic-jet-cooled 1,3-benzodioxole molecules has been investigated.
1,3-Benzodioxole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,3-Benzodioxole manufacturers
- Product
- 1,3-Benzodioxole 274-09-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-13
- Product
- 1,3-Benzodioxole 274-09-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-30
- Product
- 1,3-Benzodioxole 274-09-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-14