4-PYRIDIN-2-YL-THIAZOL-2-YLAMINE
- Product Name
- 4-PYRIDIN-2-YL-THIAZOL-2-YLAMINE
- CAS No.
- 30235-26-8
- Chemical Name
- 4-PYRIDIN-2-YL-THIAZOL-2-YLAMINE
- Synonyms
- BUTTPARK 29\06-84;IFLAB-BB F0447-0233;TIMTEC-BB SBB010613;4-(2-pyridyl)thiazol-2-amine;4-(2-pyridyl)-2-thiazolamine;2-AMINO-4-(2-PYRIDYL)THIAZOLE;4-(2-Pyridinyl)-2-thiazolamine;4-(2-Pyridinyl)thiazol-2-amine;4-(Pyridin-2-yl)thiazol-2-amine;4-PYRIDIN-2-YL-THIAZOL-2-YLAMINE
- CBNumber
- CB5741618
- Molecular Formula
- C8H7N3S
- Formula Weight
- 177.23
- MOL File
- 30235-26-8.mol
4-PYRIDIN-2-YL-THIAZOL-2-YLAMINE Property
- Melting point:
- 173-174 °C(Solv: ethanol, 50% (64-17-5))
- Boiling point:
- 383.6±17.0 °C(Predicted)
- Density
- 1.333±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- form
- Solid
- pka
- 3.40±0.10(Predicted)
- color
- Pale brown
Safety
- HazardClass
- IRRITANT
- HS Code
- 2934100090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- P841158
- Product name
- 4-Pyridin-2-yl-thiazol-2-ylamine
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- P841158
- Product name
- 4-Pyridin-2-yl-thiazol-2-ylamine
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- P841158
- Product name
- 4-Pyridin-2-yl-thiazol-2-ylamine
- Packaging
- 250mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 032629
- Product name
- 4-Pyridin-2-yl-thiazol-2-ylamine
- Packaging
- 500mg
- Price
- $59
- Updated
- 2021/12/16
- Product number
- J50437
- Product name
- 4-Pyridin-2-yl-thiazol-2-ylamine
- Packaging
- 100mg
- Price
- $13
- Updated
- 2021/12/16
4-PYRIDIN-2-YL-THIAZOL-2-YLAMINE Chemical Properties,Usage,Production
Synthesis
40086-66-6
17356-08-0
30235-26-8
General procedure for the synthesis of 4-(pyridin-2-yl)thiazol-2-amine from 2-bromo-1-(2-pyridinyl)ethanone and thiourea (CAS: 17356-08-0): 2-bromo-1-(2-pyridinyl)ethanone (0.01 mol, ca. 0.76 g), thiourea (0.01 mol), and 50 mL of ethanol were added to a 100 mL round-bottomed flask, and the mixture was heated to reflux for for 4 hours. After completion of the reaction, the ethanol solvent was removed by distillation under reduced pressure. The crude product was purified by column chromatography using dichloromethane (DCM): methanol (MeOH): ammonium hydroxide (NH4OH) (20:1:0.1, v/v) as mobile phase. 4-(Pyridin-2-yl)thiazol-2-amine was finally obtained as a white solid in a yield of 1.41 g in 79.6%.
References
[1] Patent: CN105820163, 2016, A. Location in patent: Paragraph 0127 - 0129
[2] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 2, p. 560 - 564
[3] Patent: WO2008/122787, 2008, A1. Location in patent: Page/Page column 85
[4] Journal of Heterocyclic Chemistry, 1970, vol. 7, p. 1137 - 1141
[5] Journal of the Chinese Chemical Society, 2017, vol. 64, # 12, p. 1408 - 1416
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View Lastest Price from 4-PYRIDIN-2-YL-THIAZOL-2-YLAMINE manufacturers
- Product
- 4-PYRIDIN-2-YL-THIAZOL-2-YLAMINE 30235-26-8
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2019-12-26