ITE
- Product Name
- ITE
- CAS No.
- 448906-42-1
- Chemical Name
- ITE
- Synonyms
- ITE;ARYL HYDROCARBON RECEPTOR LIGAND;ITE,Aryl Hydrocarbon Receptor,Inhibitor,inhibit,AhR;Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate;2-(1'H-INDOLE-3'-CARBONYL)-THIAZOLE-4-CARBOXYLIC ACID;methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate;2-(1H-INDOL-3-YLCARBONYL)-4-THIAZOLECARBOXYLIC ACID METHYL ESTER;2-(1'H-indole-37-carbonyl)-thiasole-4-carboxylic acid methyl ester;4-Thiazolecarboxylic acid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester
- CBNumber
- CB5754713
- Molecular Formula
- C14H10N2O3S
- Formula Weight
- 286.31
- MOL File
- 448906-42-1.mol
ITE Property
- Melting point:
- 234 - 236°C
- Boiling point:
- 520.4±48.0 °C(Predicted)
- Density
- 1.427±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 30 mg/mL, soluble
- form
- solid
- pka
- 14.38±0.30(Predicted)
- color
- Off-White to Light Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 1803
- Product name
- ITE
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $231
- Updated
- 2021/12/16
- Product number
- 452797
- Product name
- ITE
- Packaging
- 1mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- I942030
- Product name
- ITE
- Packaging
- 1mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-5141
- Product name
- ITE
- Purity
- 99.27%
- Packaging
- 5mg
- Price
- $119
- Updated
- 2021/12/16
- Product number
- A8615
- Product name
- ITE
- Packaging
- 10mg
- Price
- $158
- Updated
- 2021/12/16
ITE Chemical Properties,Usage,Production
Uses
ITE is an endogenous AHR ligand that parenterally or orally induces FoxP3+ Treg that suppress exprimental autoimmune encephalomyelitis. ITE promotes the induction of active immunology tolerance and identifies nontoxic endogenous AHR ligands.
Definition
ChEBI: 2-[1H-indol-3-yl(oxo)methyl]-4-thiazolecarboxylic acid methyl ester is an indolyl carboxylic acid.
Biological Activity
Endogenous agonist for the transcription factor aryl hydrocarbon receptor (AHR); K i = 3 nM for binding to murine AHR. Transactivates DRE-containing reporter gene constructs in Hepa1c1c7 cells ~ 5-fold more potently than β -naphthoflavone. Active in vivo .
storage
Store at RT
ITE Preparation Products And Raw materials
Raw materials
Preparation Products
ITE Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from ITE manufacturers
- Product
- ITE 448906-42-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24