4-Thiazolecarboxylic acid

Product Name: 4-Thiazolecarboxylic acid
CAS No.: 3973-08-8
Chemical Name: 4-Thiazolecarboxylic acid
Synonyms: THIAZOLE-4-CARBOXYLIC ACID;3973/8/8;NSC 195467;AKOS BB-9161;4-CARBOXYTHIAZOLE;TIMTEC-BB SBB010166;4-Carboxy-1,3-thiazole;4-THIAZOLECARBOXYLIC ACID;4-Thiazolecarboxylic acid 97%;1,3-THIAZOLE-4-CARBOXYLIC ACID
CBNumber: CB5769438
Molecular Formula: C4H3NO2S
Formula Weight: 129.14
MOL File: 3973-08-8.mol

More

Less

4-Thiazolecarboxylic acid Property

Melting point:: 195-199 °C (lit.)
Boiling point:: 191 °C
Density: 1.525±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 3.57±0.10(Predicted)
color: White to Off-White
λmax: 230nm(EtOH)(lit.)
InChI: InChI=1S/C4H3NO2S/c6-4(7)3-1-8-2-5-3/h1-2H,(H,6,7)
InChIKey: HMVYYTRDXNKRBQ-UHFFFAOYSA-N
SMILES: S1C=C(C(O)=O)N=C1
CAS DataBase Reference: 3973-08-8(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29341000

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H317May cause an allergic skin reaction
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 633658
Product name: 4-Thiazolecarboxylic acid
Purity: 97%
Packaging: 1g
Price: $22.61
Updated: 2025/07/31

Sigma-Aldrich

Product number: 633658
Product name: 4-Thiazolecarboxylic acid
Purity: 97%
Packaging: 5g
Price: $93.8
Updated: 2025/07/31

TCI Chemical

Product number: T2494
Product name: Thiazole-4-carboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $71
Updated: 2025/07/31

TCI Chemical

Product number: T2494
Product name: Thiazole-4-carboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $210
Updated: 2025/07/31

TRC

Product number: T344195
Product name: 4-Thiazolecarboxylic acid
Packaging: 10g
Price: $950
Updated: 2021/12/16

More

Less

4-Thiazolecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Pale yellow to white solid

Uses

4-Thiazolecarboxylic Acid (cas# 3973-08-8) is a compound useful in organic synthesis.

Synthesis

693-95-8

3973-08-8

The general procedure for the synthesis of thiazole-4-carboxylic acid from 4-methylthiazole was as follows: 4-methylthiazole (19.8 g, 0.2 mol), 200 mL of water, and potassium permanganate (173.8 g, 1.1 mol) were added to a 500 mL three-necked flask, which was heated to 55 °C with stirring and kept for 22 hours. After completion of the reaction, the reaction mixture was cooled and filtered. The filter cake (mainly composed of manganese dioxide) was washed with hot water at 50°C. The filtrate was adjusted to pH 3 with dilute hydrochloric acid, precipitated as a solid and filtered. The filter cake was washed with a small amount of water and dried to give 18.1 g of thiazole-4-carboxylic acid in 70.2% yield, melting point 196-198 °C.

References

[1] Angewandte Chemie, 1992, vol. 104, # 6, p. 748 - 749
[2] Patent: CN104557902, 2018, B. Location in patent: Paragraph 0063; 0076; 0081; 0088; 0089; 0102

4-Thiazolecarboxylic acid Preparation Products And Raw materials

Raw materials

THIOFORMAMIDE Pyruvic acid Methyl Bromopyruvate METHYL 4-THIAZOLECARBOXYLATE 1,2-Dimethoxyethane

Preparation Products

More

Less

4-Thiazolecarboxylic acid Suppliers

Belgium 1 Canada 1 China 247 France 1 Germany 7 India 7 Japan 4 Russia 1 Slovakia 1 South Korea 1 Switzerland 1 The Netherlands 1 United Kingdom 17 United States 34 Global 324

Cangzhou Huiying Pharmaceutical Technology Co. , Ltd.

Tel: 15532866377
Email: 294989518@qq.com
Country: China
ProdList: 20
Advantage: 58

Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd.

Tel: 21-54820552 18964669552
Fax: 086-21-64964478
Email: 188738128@qq.com
Country: China
ProdList: 310
Advantage: 66

Xishi Chemical (Shanghai) Co., Ltd.

Tel: 021-60499358 13661956116
Fax: +86 (21) 5106-9359
Email: info@cs-pharm.com
Country: China
ProdList: 223
Advantage: 58

Yancheng Schiemann Biological Technology Co.,Ltd

Tel: 515-88280676 18921872653
Email: sales@ximanbio.com
Country: China
ProdList: 1524
Advantage: 56

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

More

Less

View Lastest Price from 4-Thiazolecarboxylic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Thiazolecarboxylic acid 3973-08-8
Price: US $9.90/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-12-03

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Thiazolecarboxylic acid 3973-08-8
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 2000tons
Release date: 2019-12-31

Career Henan Chemical Co

Product: 4-Thiazolecarboxylic acid 3973-08-8
Price: US $8.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-15

3973-08-8, 4-Thiazolecarboxylic acidRelated Search:

2-(2-Aminothiazol-4-yl)glyoxylic acid 2-Mercaptobenzothiazole Thiazole Benzothiazole 2,2'-Dithiobis(benzothiazole) Fosthiazate Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) 5-THIAZOLECARBOXYLIC ACID Thiazole-4-carboxaldehyde THIAZOLE-2-CARBOXYLIC ACID THIAZOLE-4-CARBOXAMIDE 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Ethyl thiazole-5-carboxylate 2-THIAZOLE-4-BORONIC ACID THIAZOLO[5,4-B]PYRIDIN-2-AMINE Ethyl thiazole-2-carboxylate thiazol-4-ylboronic acid pinacol ester C-THIAZOL-4-YL-METHYLAMINE HYDROCHLORIDE

4-Thiazolecarboxylic acid 3973-8-8

1,3-Thiazole-4-Carboxylic Acid 3973-8-8

1,3-thiazole-4-carboxylic acid(SALTDATA: FREE)

4-Carboxy-1,3-thiazole

NSC 195467

4-Thiazolecarboxylic acid 97%

4-Thiazolecarboxylic Acid, 97+%

3973/8/8

1,3-THIAZOLE-4-CARBOXYLIC ACID

AKOS BB-9161

4-CARBOXYTHIAZOLE

4-THIAZOLECARBOXYLIC ACID

TIMTEC-BB SBB010166

THIAZOLE-4-CARBOXYLIC ACID

3973-08-8

3937-08-8

3973-08-6

3973-8-8

3973/8/8

757-36-9

C4H3NO2S

Building Blocks

Thiazoles

Heterocyclic Building Blocks

Carboxylic Acids

Thiazoles, Isothiazoles & Benzothiazoles

Thiazoles

Sulphur Derivatives

Carboxylic Acids

Thiazoles, Isothiazoles &Benzothiazoles

Heterocycles

Miscellaneous Reagents

Sulfur & Selenium Compounds

Building Blocks

Heterocyclic Building Blocks

blocks

Carboxes

bc0001