4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID
- Product Name
- 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID
- CAS No.
- 39793-31-2
- Chemical Name
- 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID
- Synonyms
- DAO-IN-2;79793-31-2;AKOS BB-9991;CHEMBRDG-BB 4012315;D-Amino Acid Oxidase Inhibitor;Thieno[2,3-b]pyrrole-5-carboxylic acid;4-Thieno[3,2-b]pyrrole-5-carboxylic acid;4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID;4H-thieno[2,3-d]pyrrole-5-carboxylic acid;4H-thieno[3,2-b]pyrrole-5-carboxylic acid(SALTDATA: FREE)
- CBNumber
- CB9349944
- Molecular Formula
- C7H5NO2S
- Formula Weight
- 167.19
- MOL File
- 39793-31-2.mol
4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Property
- Melting point:
- 180 °C
- Boiling point:
- 437.4±25.0 °C(Predicted)
- Density
- 1.609
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 2 mg/ml
- pka
- 4.36±0.30(Predicted)
- form
- Beige solid
- color
- Light brown to gray
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 22-26-36/37/39
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 760250
- Product name
- 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid
- Purity
- 97%
- Packaging
- 500mg
- Price
- $31.6
- Updated
- 2023/06/20
- Product number
- 138000
- Product name
- D-Amino Acid Oxidase Inhibitor
- Packaging
- 50mg
- Price
- $110
- Updated
- 2023/01/07
- Product number
- H58200
- Product name
- 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 97%
- Packaging
- 1g
- Price
- $201.65
- Updated
- 2024/03/01
- Product number
- H58200
- Product name
- 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 97%
- Packaging
- 5g
- Price
- $770
- Updated
- 2021/12/16
- Product number
- 23894
- Product name
- D-Amino Acid Oxidase Inhibitor
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $68
- Updated
- 2024/03/01
4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis Reference(s)
Journal of the American Chemical Society, 79, p. 2556, 1957 DOI: 10.1021/ja01567a053
General Description
A cell-permeable thienopyrrole compound that potently inhibits the cellular activity of transfected D-amino acid oxidase (DAO/DAAO/DAMOX/OXDA) in CHO cells (IC50 against human and rat DAO = 145 and 114 nM, respectively), while exhibiting no activity towards D-aspartate oxidase (DDO; IC50 >5 μM), P450 enzymes CYP3A4/2D6/3C9 (IC50 >10 μM), and a panel of over 150 other enzymes, receptors, and ion channels. Although in vivo treatment of Compound 8 (200 mg/kg, i.p.) is shown to effectively inhibit DAO activity in rat brain and kidney (by 96% and 80%, respectively), the resulting D-serine concentration increase in the periphery and central nervous system appears to be far from sufficient to produce adequate antipsychotic and cognitive enhancing effects.
4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID manufacturers
- Product
- 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID 39793-31-2
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24