THIAZOLE-2-CARBOXYLIC ACID

Product Name: THIAZOLE-2-CARBOXYLIC ACID
CAS No.: 14190-59-1
Chemical Name: THIAZOLE-2-CARBOXYLIC ACID
Synonyms: Thiazolic acid;2-Carboxythiazole;RARECHEM AL BE 0750;2-THIAZOLECARBOXYLIC;Thiazole formic acid;2-Carboxy-1,3-thiazole;Thiazole-2- forMic acid;Thiazole-2-carboxylicaci;thiazol-2-carboxylic acid;THIAZOLE-2-CARBOXYLIC ACID
CBNumber: CB6758187
Molecular Formula: C4H3NO2S
Formula Weight: 129.14
MOL File: 14190-59-1.mol

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THIAZOLE-2-CARBOXYLIC ACID Property

Melting point:: 91.6-93°C
Boiling point:: 310.6±25.0 °C(Predicted)
Density: 1.525±0.06 g/cm3(Predicted)
storage temp.: -20°C
pka: 2.95±0.10(Predicted)
form: Solid
Appearance: White to off-white Solid
Water Solubility: Slightly soluble in water.
CAS DataBase Reference: 14190-59-1(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39-22
WGK Germany: 1
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 734748
Product name: Thiazole-2-carboxylic acid
Packaging: 1g
Price: $91.7
Updated: 2025/07/31

Usbiological

Product number: 289874
Product name: 1,3-Thiazole-2-carboxylic acid
Packaging: 1g
Price: $307
Updated: 2021/12/16

TRC

Product number: B585373
Product name: Thiazole-2-carboxylic acid
Packaging: 2.5g
Price: $155
Updated: 2021/12/16

Ark Pharm

Product number: P000107864
Product name: Thiazole-2-carboxylic acid
Purity: 97%
Packaging: 25g
Price: $198
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC67666
Product name: 2-Carboxythiazole
Packaging: 50g
Price: $350
Updated: 2021/12/16

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THIAZOLE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

Beige to light yellow powder

Uses

Thiazole-2-carboxylic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Synthesis

14527-42-5

14190-59-1

General procedure for the synthesis of thiazole-2-carboxylic acid from ethyl 2-thiazolecarboxylate: 2N aqueous KOH solution (3.5 mL, 5 eq.) was added to a solution of ethyl 2-thiazolecarboxylate (213 mg, 1.355 mmol) in ethanol (3 mL) at 116 °C. The reaction mixture was stirred at room temperature for 2 hours and then acidified with 2N HCl (3.5 mL). The acidified mixture was allowed to stand overnight and needle-like crystals were precipitated and collected by filtration to give thiazole-2-carboxylic acid (43.3 mg, 25% yield).

References

[1] Patent: US2007/185056, 2007, A1. Location in patent: Page/Page column 49
[2] Helvetica Chimica Acta, 1945, vol. 28, p. 924
[3] Patent: WO2008/76243, 2008, A2. Location in patent: Page/Page column 75
[4] Patent: WO2008/85316, 2008, A1. Location in patent: Page/Page column 73
[5] Patent: WO2006/138373, 2006, A2. Location in patent: Page/Page column 128-129

THIAZOLE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

2-Bromothiazole Carbon dioxide Tetrahydrofuran Diethyl ether Hydrochloric acid n-Butyllithium

Preparation Products

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THIAZOLE-2-CARBOXYLIC ACID Suppliers

Belgium 1 China 182 France 1 Germany 3 India 7 Japan 1 United Kingdom 6 United States 22 Global 223

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

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View Lastest Price from THIAZOLE-2-CARBOXYLIC ACID manufacturers

PNP Biotech Co. Ltd

Product: Thiazole-2-carboxylic acid 14190-59-1
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2023-07-12

Honest Joy Holdings Limited

Product: Thiazole-2-carboxylic acid 14190-59-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.5%
Supply Ability: 100 tons
Release date: 2022-01-26

Career Henan Chemical Co

Product: THIAZOLE-2-CARBOXYLIC ACID 14190-59-1
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-10

14190-59-1, THIAZOLE-2-CARBOXYLIC ACIDRelated Search:

1,3-THIAZOLE-5-CARBOXYLIC ACID 1-Benzyl-4-phenyl-pyrrolidine-3-carboxylic acid THIOMORPHOLINE-2-CARBOXYLICACID ETHYL THIAZOLE-4-CARBOXYLATE THIENO[3,2-B]THIOPHENE-2-CARBOXYLIC ACID 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole 1,3-THIAZOLE-2-BORONIC ACID 4-Thiazolecarboxylic acid Thiazole-4-carboxaldehyde Thiazole-5-carboxaldehyde THIAZOLE-4-CARBOXAMIDE THIAZOLE-2-CARBOXYLIC ACID Carbamic acid, N-(4-bromo-2-thiazolyl)-, 1,1-dimethylethyl ester ETHYL 2-BROMO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE 5-BROMO-2-PHENYLTHIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER Ethyl 2-amino-5-(3-chlorophenyl)thiazole-4-carboxylate Methyl 2-amino-4-methylthiazole-5-carboxylate Ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate

1,3-THIAZOLE-2-CARBOXYLIC ACID

RARECHEM AL BE 0750

THIAZOLE-2-CARBOXYLIC ACID

2-THIAZOLECARBOXYLIC ACID,THIAZOLE-2-CARBOXYLIC ACID

Thiazole-2-carboxylic acid ,98%

2-THIAZOLECARBOXYLIC

2-Carboxy-1,3-thiazole

thiazol-2-carboxylic acid

Thiazole-<WBR>2-<WBR>carboxylic acid

Thiazole-2- forMic acid

2-Carboxythiazole

Thiazole-2-carboxylicacid,95%

Thiazole-2-carboxylicaci

2-Thiazolecarboxylic acid (6CI, 8CI, 9CI, ACI)

Thiazole formic acid

Thiazolic acid

14190-59-1

14190-54-1

Carboxylic Acids

Thiazoles, Isothiazoles & Benzothiazoles

Carboxylic Acids

Thiazoles, Isothiazoles &Benzothiazoles

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

Thiazole series