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(+)-PHYLLODULCIN

Product Name
(+)-PHYLLODULCIN
CAS No.
21499-23-0
Chemical Name
(+)-PHYLLODULCIN
Synonyms
PHYLLODUCIN;PHYLLODULCIN;Praeruptorin;(+)-PHYLLODULCIN;(+)-Praeruptorin;(+)-PHYLLODULCIN;(3R)-Phyllodulcin;R-(+)-Phyllodulcin;(+)-PHYLLODULCIN USP/EP/BP;(R)-8-Hydroxy-3-(3-Hydroxy-4-Methoxyphenyl)Isochroman-1-One
CBNumber
CB5764271
Molecular Formula
C16H14O5
Formula Weight
286.28
MOL File
21499-23-0.mol
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(+)-PHYLLODULCIN Property

form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PXT0001005
Product name
(+)-PHYLLODULCIN
Purity
95.00%
Packaging
50MG
Price
$3902.72
Updated
2021/12/16
Crysdot
Product number
CD11165579
Product name
(R)-8-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)isochroman-1-one
Purity
95+%
Packaging
50mg
Price
$1450
Updated
2021/12/16
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(+)-PHYLLODULCIN Chemical Properties,Usage,Production

Uses

Phyllodulcin is an orally active sweetener found in Hydrangea macrophylla var. thunbergii. Phyllodulcin acts as a non-selective phosphodiesterase inhibitor and exerts anti-allergic effects by suppressing lymphocyte activation. Phyllodulcin can be used to combat obesity by regulating levels of leptin, fat browning-related genes, and hypothalamic BDNF-TrkB signaling[1][2].

Definition

ChEBI: Phyllodulcin is a hydroxybenzoic acid.

References

[1] Liu J, et al. Medicinal flowers. XXXX . Structures of dihydroisocoumarin glycosides and inhibitory effects on aldose reducatase from the flowers of Hydrangea macrophylla var.thunbergii. Chem Pharm Bull (Tokyo). 2013;61(6):655-61. DOI:10.1248/cpb.c13-00160
[2] Kim E, et al. Phyllodulcin, a Natural Sweetener, Regulates Obesity-Related Metabolic Changes and Fat Browning-Related Genes of Subcutaneous White Adipose Tissue in High-Fat Diet-Induced Obese Mice. Nutrients. 2017 Sep 21;9(10):1049. DOI:10.3390/nu9101049

(+)-PHYLLODULCIN Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-PHYLLODULCIN Suppliers

China 23 Japan 1 Ukraine 1 United Kingdom 2 United States 3 USA 1 Global 31
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80

21499-23-0, (+)-PHYLLODULCINRelated Search:

Bletillae Rhizoma lycii Fructus Psoralen Angelicae Sinensis Radix Vaccariae Semen Ophiopogonis Radix RADIX SCUTELLARIAE Forsythiae Fructus Benzyl salicylate Isopropyl salicylate 2-Bibenzylcarboxylic acid 3,4-dihydro-1H-2-benzopyran-1-one (+)-PHYLLODULCIN hydrangenol 6-METHYLSALICYLIC ACID ETHYL ESTER 1H-2-BENZOPYRAN-1-ONE, 3,4-DIHYDRO-8-HYDROXY- 3-PHENYL-3,4-DIHYDROISOCOUMARIN

  • (3R)-3-(3-Hydroxy-4-methoxyphenyl)-8-hydroxyisochroman-1-one
  • (3R)-3β-(3-Hydroxy-4-methoxyphenyl)-8-hydroxy-3,4-dihydro-1H-2-benzopyran-1-one
  • (3R)-Phyllodulcin
  • PHYLLODULCIN
  • (R)-3,4-Dihydro-8-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-1H-2-benzopyran-1-one
  • R-(+)-Phyllodulcin
  • (+)-Praeruptorin
  • Praeruptorin
  • (R)-8-Hydroxy-3-(3-Hydroxy-4-Methoxyphenyl)Isochroman-1-One
  • PHYLLODUCIN
  • (+)-PHYLLODULCIN
  • (R)-8-Hydroxy-3-(3-Hydroxy-4-Methoxyphenyl)Isochroman-1-One(WXC00795)
  • 1H-2-Benzopyran-1-one, 3,4-dihydro-8-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-, (3R)-
  • (+)-PHYLLODULCIN USP/EP/BP
  • (3R)-8-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-3,4-dihydroisochromen-1-one
  • (+)-PHYLLODULCIN
  • 21499-23-0
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