ChemicalBook > CAS DataBase List > 6-METHYLSALICYLIC ACID ETHYL ESTER

6-METHYLSALICYLIC ACID ETHYL ESTER

Product Name
6-METHYLSALICYLIC ACID ETHYL ESTER
CAS No.
6555-40-4
Chemical Name
6-METHYLSALICYLIC ACID ETHYL ESTER
Synonyms
ETHYL 2-HYDROXY-6-METHYLBENZOATE;ETHYL 6-METHYLSALICYLATE;Ethyl6-Methylsalicylate>6-Methylsalicylsureethylester;Methylsalicylicacidethylester;6-METHYLSALICYLIC ACID ETHYL ESTER;3-ethyl-2-hydroxy-6-Methylbenzoate;6-METHYLSALICYLIC ACID ETHYL ESTER 95+%;6-Methylsalicylic acid ethyl ester ,98%;2-HYDROXY-6-METHYLBENZOIC ACID ETHYL ESTER
CBNumber
CB4222864
Molecular Formula
C10H12O3
Formula Weight
180.2
MOL File
6555-40-4.mol
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6-METHYLSALICYLIC ACID ETHYL ESTER Property

Melting point:
45°C
Boiling point:
85-95 °C(Press: 0.5 Torr)
Density 
1.136±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
10.04±0.10(Predicted)
color 
White to Light yellow
InChI
InChI=1S/C10H12O3/c1-3-13-10(12)9-7(2)5-4-6-8(9)11/h4-6,11H,3H2,1-2H3
InChIKey
KWXBNUYCDMPLEQ-UHFFFAOYSA-N
SMILES
C(OCC)(=O)C1=C(C)C=CC=C1O
CAS DataBase Reference
6555-40-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
24/25
HS Code 
29182300
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M1283
Product name
Ethyl 6-Methylsalicylate
Purity
>98.0%(GC)
Packaging
5g
Price
$210
Updated
2025/07/31
TCI Chemical
Product number
M1283
Product name
Ethyl 6-Methylsalicylate
Purity
>98.0%(GC)
Packaging
25g
Price
$695
Updated
2025/07/31
TRC
Product number
E936945
Product name
Ethyl2-Hydroxy-6-methylbenzoate
Packaging
50mg
Price
$60
Updated
2021/12/16
TRC
Product number
E936945
Product name
Ethyl2-Hydroxy-6-methylbenzoate
Packaging
250mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR912635
Product name
6-Methylsalicylicacidethylester
Purity
97%
Packaging
1g
Price
$109
Updated
2021/12/16
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6-METHYLSALICYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Synthesis

123-73-9

609-15-4

6555-40-4

Example 1 Preparation of ethyl 2-hydroxy-6-methylbenzoate: a stirred mixture of trans-2-butenal (21.0 g, 0.30 mol) and anhydrous sodium acetate (25.0 g, 0.30 mol) in glacial acetic acid was heated to reflux temperature under nitrogen protection. Ethyl 2-chloroacetoacetate (41.1 g, 95%, 0.25 mol) was added dropwise over 2.25 hours. The reaction mixture was continued to be heated at reflux temperature for 16 h. Subsequently, it was cooled to room temperature and concentrated in vacuum to give the crude product. The crude product was partitioned between ethyl acetate and water. The organic phase was diluted with hexane and washed sequentially with water and aqueous sodium bicarbonate, and finally concentrated in vacuum to afford the target product ethyl 2-hydroxy-6-methylbenzoate as an oil in a yield of 41.0 g with a purity of 71.4% (65% yield), and the product structure was confirmed by nuclear magnetic resonance (NMR) analysis.

References

[1] Patent: US6441219, 2002, B1

6-METHYLSALICYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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6-METHYLSALICYLIC ACID ETHYL ESTER Suppliers

Changzhou Tianrui Pharmaceutical Technology Co., Ltd.
Tel
0519-85386832 13382812559
Fax
0519-85386832
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sales@cztrchem.com
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China
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1185
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56
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
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86-21-61259102
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market03@meryer.com
Country
China
ProdList
40228
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
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Sales-CN@TCIchemicals.com
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China
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24529
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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isenchem@163.com
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China
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Shandong Xiya Chemical Co., Ltd
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Shanghai Ennopharm Co., Ltd.
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+86 (21) 6435-5022
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China
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China Langchem Inc.
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0086-21-58956006
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0086-21-58956100
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China
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Tianjin heowns Biochemical Technology Co., Ltd.
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China
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View Lastest Price from 6-METHYLSALICYLIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co
Product
6-METHYLSALICYLIC ACID ETHYL ESTER 6555-40-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2018-08-06

6555-40-4, 6-METHYLSALICYLIC ACID ETHYL ESTERRelated Search:


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