BISTRIFLUOROACETAMIDE Property

Melting point:

80-86 °C

Boiling point:

120 °C / 1mmHg

Density 

1.603±0.06 g/cm3(Predicted)

solubility 

almost transparency in hot Toluene

form 

powder to crystal

pka

3.04±0.46(Predicted)

color 

White to Almost white

BRN 

1793118

CAS DataBase Reference

407-24-9(CAS DataBase Reference)

EPA Substance Registry System

Perfluorodiacetamide (407-24-9)

Safety

Hazard Codes 

C

Risk Statements 

36/37/38-36/38

Safety Statements 

26-36/37/39

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

F 

3-10-21

HazardClass 

8

PackingGroup 

III

HS Code 

29251900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

BISTRIFLUOROACETAMIDE Chemical Properties,Usage,Production

Purification Methods

A major impurity is trifluoroacetamide. Add trifluoroacetic anhydride to BTFA, reflux for 2hours and fractionate using a Vigreux column (p 11) at atmospheric pressure. [Donike J Chromatogr 78 273 1973, Beilstein 2 IV 471.]