ChemicalBook > CAS DataBase List > SU 9516

SU 9516

Product Name
SU 9516
CAS No.
666837-93-0
Chemical Name
SU 9516
Synonyms
SU 9516;(E/Z)-SU9516;3-((1H-Imidazol-5-yl)methylene)-5-methoxyindolin-2-one;(Z)-3-((1H-iMidazol-5-yl)Methylene)-5-Methoxyindolin-2-one;1,3-Dihydro-3-(1H-imidazol-5-ylmethylene)-5-methoxy-2H-indol-2-one;2H-Indol-2-one, 1,3-dihydro-3-(1H-imidazol-5-ylmethylene)-5-methoxy-;SU 9516;SU9516;(Z)-3-((1H-IMIDAZOL-5-YL)METHYLENE)-5-METHOXYINDOLIN-2-ONE;3-[1-(3H-IMIDAZOL-4-YL)-METH-(Z)-YLIDENE]-5-METHOXY-1,3-DIHYDRO-INDOL-2-ONE
CBNumber
CB5765692
Molecular Formula
C13H11N3O2
Formula Weight
241.25
MOL File
Mol file
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SU 9516 Property

Boiling point:
601.5±55.0 °C(Predicted)
Density 
1.383±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: ~17 mg/mL
pka
11?+-.0.20(Predicted)
form 
crystalline
color 
brown
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
572650
Product name
SU9516
Purity
A cell-permeable 3-substituted indolinone compound that displays anti-proliferative and proapoptotic properties in tumor cells.
Packaging
5mg
Price
$171
Updated
2025/07/31
Tocris
Product number
2907
Product name
SU9516
Purity
≥99%(HPLC)
Packaging
50
Price
$642
Updated
2021/12/16
TRC
Product number
S688050
Product name
SU9516
Packaging
10mg
Price
$210
Updated
2021/12/16
Usbiological
Product number
466548
Product name
SU 9516
Packaging
5mg
Price
$375
Updated
2021/12/16
Usbiological
Product number
256777
Product name
SU 9516
Packaging
10mg
Price
$403
Updated
2021/12/16
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SU 9516 Chemical Properties,Usage,Production

Uses

SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.

Uses

SU 9516 is a 3-substituted indolinone CDK inhibitor with potent and selective inhibition towards cyclin-dependant kinases.

Definition

ChEBI: 3-(1H-imidazol-5-ylmethylidene)-5-methoxy-1H-indol-2-one is a member of indoles.

Biological Activity

Cell permeable: yes', 'Primary Target
Cdk2/A', 'Product competes with ATP.', 'Reversible: yes', 'Target IC50: 22 nM for Cdk2/A; 40 nM for Cdk1/B; 200 nM for Cdk4/D1

SU 9516 Preparation Products And Raw materials

Raw materials

Preparation Products

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SU 9516 Suppliers

China 70 India 1 Switzerland 2 United States 6 Global 79
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
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0-2022843681 15618226720
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Amadis Chemical Company Limited
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571-89925085
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Energy Chemical
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View Lastest Price from SU 9516 manufacturers

Career Henan Chemical Co
Product
SU 9516 666837-93-0
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

666837-93-0, SU 9516Related Search:

SU 6656 SUN11602 SU 11274 SUFUGOLIX SU 9516

  • SU 9516
  • 3-[1-(3H-IMIDAZOL-4-YL)-METH-(Z)-YLIDENE]-5-METHOXY-1,3-DIHYDRO-INDOL-2-ONE
  • (Z)-3-((1H-iMidazol-5-yl)Methylene)-5-Methoxyindolin-2-one
  • 1,3-Dihydro-3-(1H-imidazol-5-ylmethylene)-5-methoxy-2H-indol-2-one
  • SU 9516;SU9516;(Z)-3-((1H-IMIDAZOL-5-YL)METHYLENE)-5-METHOXYINDOLIN-2-ONE
  • 3-((1H-Imidazol-5-yl)methylene)-5-methoxyindolin-2-one
  • 2H-Indol-2-one, 1,3-dihydro-3-(1H-imidazol-5-ylmethylene)-5-methoxy-
  • (E/Z)-SU9516
  • 666837-93-0