ChemicalBook > CAS DataBase List > SUN11602
SUN11602
- Product Name
- SUN11602
- CAS No.
- 704869-38-5
- Chemical Name
- SUN11602
- Synonyms
- CS-2504;SUN11602;SUN11602;SUN11602;SUN11602, 10 mM in DMSO;inhibit,Fibroblast growth factor receptor,SUN11602,FGFR,Inhibitor,SUN-11602;4-[[4-[[2-[(4-Amino-2,3,5,6-tetramethylphenyl)amino]acetyl]methylamino]-1-piperidinyl]methyl]benzamide;Benzamide, 4-[[4-[[2-[(4-amino-2,3,5,6-tetramethylphenyl)amino]acetyl]methylamino]-1-piperidinyl]methyl]-
- CBNumber
- CB52731145
- Molecular Formula
- C26H37N5O2
- Formula Weight
- 451.60428
- MOL File
- 704869-38-5.mol
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SUN11602 Property
- Boiling point:
- 679.8±55.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble
- form
- A crystalline solid
- pka
- 16.19±0.50(Predicted)
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
Tocris
- Product number
- 4826
- Product name
- SUN11602
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $219
- Updated
- 2021/12/16
Usbiological
- Product number
- 256781
- Product name
- SUN 11602
- Packaging
- 10mg
- Price
- $466
- Updated
- 2021/12/16
TRC
- Product number
- S688063
- Product name
- SUN11602
- Packaging
- 10mg
- Price
- $200
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6383
- Product name
- SUN11602
- Purity
- 99.10%
- Packaging
- 100mg
- Price
- $500
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6383
- Product name
- SUN11602
- Purity
- 99.10%
- Packaging
- 25mg
- Price
- $250
- Updated
- 2021/12/16
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SUN11602 Chemical Properties,Usage,Production
Uses
SUN 11602 is a novel aniline compound, which mimics the neuroprotective mechanisms of basic fibroblast growth factor.
Biological Activity
SUN11602 is an orally active basic fibroblast growth factor (bFGF, FGF2) mimetic th at protects against glutamate toxicity in primary r at cerebrocortical neuron (0.1-1 μM SUN11602; 150 μM glutamate) and murine hippocampal neuron cultures (0.3-3 μM SUN11602; 100 μM glutamate). When administered in vivo, SUN11602 exhibits therapeutic efficacy in a r at hippocampal-lesion model (1-10 mg/kg p.o. 24h post Aβ1-40 injection) and a murine MPTP-induced nigrostriatal degeneration model (2.5-5 mg/kg/day p.o.).
SUN11602 Preparation Products And Raw materials
Raw materials
Preparation Products
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SUN11602 Suppliers
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