3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE

Product Name: 3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE
CAS No.: 186611-55-2
Chemical Name: 3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE
Synonyms: SU 4313;SU 4313, 10 mM in DMSO;SU4313 SU-4313 SU 4313;3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE;(3e)-3-(4-isopropylbenzylidene)-1,3-dihydro-2h-indol-2-one;1,3-Dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one;2H-Indol-2-one,1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-
CBNumber: CB6379043
Molecular Formula: C18H17NO
Formula Weight: 263.33
MOL File: 186611-55-2.mol

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3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE Property

form: Yellow crystals.
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC10602
Product name: SU4313
Purity: >98%
Packaging: 1g
Price: $1620
Updated: 2021/12/16

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3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE Chemical Properties,Usage,Production

Uses

SU-4313 is a potent protein tyrosine kinases (PTKs) modulator with IC50s of 14.5 μM, 18.8 μM, 11 μM, 16.9 μM, 8.0 μM for PDGFR, FLK-1, EGFR, HER2 Kinase and IGF-1R, respectively. SU-4313 has the potential for modulating tyrosine kinase signal transduction in order to regulate abnormal cell proliferation[1].

IC 50

PDGFR: 14.5 μM (IC₅₀); FLK-1: 18.8 μM (IC₅₀); EGFR: 11 μM (IC₅₀); HER2: 16.9 μM (IC₅₀); IGF-1R: 8.0 μM (IC₅₀)

References

[1] Peng Cho Tang, et al. Indolinone compounds for the treatment of disease. WO1996040116A1.

3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE Suppliers

China 44 Switzerland 2 United Kingdom 3 United States 5 Global 54

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186611-55-2, 3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONERelated Search:

SU 5214 SUN11602 SU 4942 SU 11274 SU 5205 (E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide SU 4312 4-ISOPROPYLCINNAMALDEHYDE 4-ISO-PROPYL STYRENE N,3-DIPHENYLACRYLAMIDE 3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE

SU 4313

2H-Indol-2-one,1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-

3-(4-ISOPROPYLBENZYLIDENYL)INDOLIN-2-ONE

SU4313 SU-4313 SU 4313

(3e)-3-(4-isopropylbenzylidene)-1,3-dihydro-2h-indol-2-one

1,3-Dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one

SU 4313, 10 mM in DMSO

186611-55-2

C18H17NO

Indoles and derivatives