SU 5214
- Product Name
- SU 5214
- CAS No.
- 186611-04-1
- Chemical Name
- SU 5214
- Synonyms
- SU4949;SU 5214;SU5214 ,S6809;SU5214, 10 mM in DMSO;SU 5214;SU-5214;SU5214;3-(2-METHOXYBENZYLIDENE)-3H-INDOL-2-OL;2H-Indol-2-one, 1,3-dihydro-3-[(2-methoxyphenyl)methylene]-;FLK-1,SU5214,Vascular endothelial growth factor receptor,VEGFR,SU4949,inhibit,VEGFR2,SU 4949,SU-5214,Inhibitor,EGFR,SU-4949
- CBNumber
- CB73123196
- Molecular Formula
- C16H13NO2
- Formula Weight
- 251.28
- MOL File
- 186611-04-1.mol
SU 5214 Property
- Boiling point:
- 469.4±45.0 °C(Predicted)
- Density
- 1.238±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: 33 mg/ml; DMSO: 33 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
- form
- A crystalline solid
- pka
- 12.81±0.20(Predicted)
- color
- White to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- R772178
- Product name
- 3-(2-METHOXYBENZYLIDENE)-3H-INDOL-2-OL
- Purity
- AldrichCPR
- Packaging
- 10MG
- Price
- $30.7
- Updated
- 2025/07/31
- Product number
- 24670
- Product name
- SU 5214
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $61
- Updated
- 2024/03/01
- Product number
- 24670
- Product name
- SU 5214
- Purity
- ≥98%
- Packaging
- 50 mg
- Price
- $362
- Updated
- 2024/03/01
- Product number
- 24670
- Product name
- SU 5214
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $28
- Updated
- 2023/01/06
- Product number
- 24670
- Product name
- SU 5214
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $241
- Updated
- 2024/03/01
SU 5214 Chemical Properties,Usage,Production
Uses
SU5214 is a potent VEGFR2 inhibitor extracted from patent US5834504A, SU5214, has IC50s of 14.8 μM (FLK-1) and 36.7 μM (EGFR), respectively[1].
IC 50
Flk-1: 14.8 μM (IC50)
References
[1] Tang et al. 3-(2'-halobenzylidenyl)-2-indolinone compounds for the treatment of disease. US5834504A.
SU 5214 Preparation Products And Raw materials
Raw materials
Preparation Products
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