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CIVENTICHEM CV-409

Product Name
CIVENTICHEM CV-409
CAS No.
186610-89-9
Chemical Name
CIVENTICHEM CV-409
Synonyms
CIVENTICHEM CV-409;SU4984, 10 mM in DMSO;1-Piperazinecarboxaldehyde, 4-[4-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]phenyl]-;inhibit,growth,Fibroblast growth factor receptor,Insulin Receptor,fibroblast,insulin,SU4984,SU 4984,FGFR1,factor,Platelet-derived growth factor receptor,SU-4984,FGFR,kinase,tyrosine,platelet,cancer,PDGFR,Inhibitor
CBNumber
CB5138241
Molecular Formula
C20H19N3O2
Formula Weight
333.38
MOL File
186610-89-9.mol
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CIVENTICHEM CV-409 Property

Boiling point:
649.1±55.0 °C(Predicted)
Density 
1.340±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
DMSO : 50 mg/mL (149.98 mM)
form 
Orange to red crystalline solid.
pka
12.93±0.20(Predicted)
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

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CIVENTICHEM CV-409 Chemical Properties,Usage,Production

Uses

SU4984 is a protein tyrosine kinase inhibitor, with an IC50 of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits platelet-derived growth factor receptor, and insulin receptor. SU4984 can be used for the research of cancer[1][2][3].

IC 50

FGFR1: 10-20 μM (IC50)

References

[1] Mohammadi M, et, al. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science. 1997 May 9;276(5314):955-60. DOI:10.1126/science.276.5314.955
[2] Ma Y, et, al. Indolinone derivatives inhibit constitutively activated KIT mutants and kill neoplastic mast cells. J Invest Dermatol. 2000 Feb;114(2):392-4. DOI:10.1046/j.1523-1747.2000.00888.x

CIVENTICHEM CV-409 Preparation Products And Raw materials

Raw materials

Preparation Products

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CIVENTICHEM CV-409 Suppliers

China 15 United States 4 Global 19
ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
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China
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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32435
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
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psaitong@jm-bio.com
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China
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29757
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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24961
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627
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customer_service@efebio.com
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China
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https://hanhongsci.com/
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021-54306202 18917919676
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info@hanhongsci.com
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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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021-59167510 18117107507
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vip@med-life.cn
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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
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025-85563444
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RD International Technology Co., Limited
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18024082417
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market@ubiochem.com
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Sangon Biotech (Shanghai) Co.,Ltd.
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400-821-026
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Sales@sangon.com
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186610-89-9, CIVENTICHEM CV-409Related Search:

SU 4312 SU5402 (E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide TYRPHOSTIN B48 2-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]- 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE PD168393 TYRPHOSTIN A51 AG 213 AG 1478 HYDROCHLORIDE DAPH AG 18 LAVENDUSTIN A METHYL 2,5-DIHYDROXYCINNAMATE H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH AG 825 TYRPHOSTIN A25 SU14813

  • CIVENTICHEM CV-409
  • inhibit,growth,Fibroblast growth factor receptor,Insulin Receptor,fibroblast,insulin,SU4984,SU 4984,FGFR1,factor,Platelet-derived growth factor receptor,SU-4984,FGFR,kinase,tyrosine,platelet,cancer,PDGFR,Inhibitor
  • 1-Piperazinecarboxaldehyde, 4-[4-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]phenyl]-
  • SU4984, 10 mM in DMSO
  • 186610-89-9