DAPH

Product Name: DAPH
CAS No.: 145915-58-8
Chemical Name: DAPH
Synonyms: DAPH-1 (DAPH;DAPH/CGP 52411;DAPH >=98% (HPLC), solid;1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-;4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411
CBNumber: CB2498023
Molecular Formula: C20H15N3O2
Formula Weight: 329.35
MOL File: 145915-58-8.mol

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DAPH Property

Melting point:: 199-202℃
Density: 1.374
storage temp.: 2-8°C
solubility: DMSO: ~30 mg/mL
form: solid
pka: 9.06±0.20(Predicted)
color: orange

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Safety

Safety Statements: 36/37
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H303May be harmfulif swallowed
Precautionary statements: P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D3943
Product name: DAPH
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $198
Updated: 2024/03/01

Sigma-Aldrich

Product number: D3943
Product name: DAPH
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $630
Updated: 2024/03/01

Cayman Chemical

Product number: 29196
Product name: DAPH
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 29196
Product name: DAPH
Packaging: 25mg
Price: $651
Updated: 2024/03/01

Cayman Chemical

Product number: 29196
Product name: DAPH
Packaging: 5mg
Price: $156
Updated: 2024/03/01

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DAPH Chemical Properties,Usage,Production

Uses

CGP 52411 is a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitmuor activity. It may offer therapeutic agents for the treatment of hyperproliferative diseases.

Definition

ChEBI: 4,5-dianilinophthalimide is phthalimide substituted at the 4- and 5-positions by anilino groups. It has a role as a tyrosine kinase inhibitor and a geroprotector.

Biochem/physiol Actions

DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR.

DAPH Preparation Products And Raw materials

Raw materials

Preparation Products

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DAPH Suppliers

China 22 Switzerland 1 United Kingdom 2 United States 8 Global 33

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 4601
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28809
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11217
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44808
Advantage: 58

145915-58-8, DAPHRelated Search:

TYRPHOSTIN B48 2-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]- 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE PD168393 TYRPHOSTIN A51 AG 213 CIVENTICHEM CV-409 AG 1478 HYDROCHLORIDE AG 18 LAVENDUSTIN A METHYL 2,5-DIHYDROXYCINNAMATE H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH AG 825 TYRPHOSTIN A25 Canertinib

DAPH-1 (DAPH

DAPH/CGP 52411

4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411

1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-

DAPH >=98% (HPLC), solid

145915-58-8