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DAPH

Product Name
DAPH
CAS No.
145915-58-8
Chemical Name
DAPH
Synonyms
DAPH-1 (DAPH;DAPH/CGP 52411;DAPH >=98% (HPLC), solid;1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-;4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411
CBNumber
CB2498023
Molecular Formula
C20H15N3O2
Formula Weight
329.35
MOL File
145915-58-8.mol
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DAPH Property

Melting point:
199-202℃
Density 
1.374
storage temp. 
2-8°C
solubility 
DMSO: ~30 mg/mL
form 
solid
pka
9.06±0.20(Predicted)
color 
orange
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Safety

Safety Statements 
36/37
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

Precautionary statements

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D3943
Product name
DAPH
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$198
Updated
2024/03/01
Sigma-Aldrich
Product number
D3943
Product name
DAPH
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$630
Updated
2024/03/01
Cayman Chemical
Product number
29196
Product name
DAPH
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
29196
Product name
DAPH
Packaging
25mg
Price
$651
Updated
2024/03/01
Cayman Chemical
Product number
29196
Product name
DAPH
Packaging
5mg
Price
$156
Updated
2024/03/01
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DAPH Chemical Properties,Usage,Production

Uses

CGP 52411 is a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitmuor activity. It may offer therapeutic agents for the treatment of hyperproliferative diseases.

Definition

ChEBI: 4,5-dianilinophthalimide is phthalimide substituted at the 4- and 5-positions by anilino groups. It has a role as a tyrosine kinase inhibitor and a geroprotector.

Biochem/physiol Actions

DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR.

DAPH Preparation Products And Raw materials

Raw materials

Preparation Products

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DAPH Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2784
Advantage
58
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
3445
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28821
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58

145915-58-8, DAPHRelated Search:


  • DAPH-1 (DAPH
  • DAPH/CGP 52411
  • 4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411
  • 1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-
  • DAPH >=98% (HPLC), solid
  • 145915-58-8