DAPH

Product Name: DAPH
CAS No.: 145915-58-8
Chemical Name: DAPH
Synonyms: DAPH-1 (DAPH;DAPH/CGP 52411;CGP52411, 10 mM in DMSO;DAPH >=98% (HPLC), solid;1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-;4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411
CBNumber: CB2498023
Molecular Formula: C20H15N3O2
Formula Weight: 329.35
MOL File: 145915-58-8.mol

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DAPH Property

Melting point:: 199-202℃
Density: 1.374
storage temp.: 2-8°C
solubility: DMSO: ~30 mg/mL
form: solid
pka: 9.06±0.20(Predicted)
color: orange

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Safety

Safety Statements: 36/37
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H303May be harmfulif swallowed
Precautionary statements: P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D3943
Product name: DAPH
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $198
Updated: 2024/03/01

Sigma-Aldrich

Product number: D3943
Product name: DAPH
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $630
Updated: 2024/03/01

Cayman Chemical

Product number: 29196
Product name: DAPH
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 29196
Product name: DAPH
Packaging: 25mg
Price: $651
Updated: 2024/03/01

Cayman Chemical

Product number: 29196
Product name: DAPH
Packaging: 5mg
Price: $156
Updated: 2024/03/01

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DAPH Chemical Properties,Usage,Production

Uses

CGP 52411 is a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitmuor activity. It may offer therapeutic agents for the treatment of hyperproliferative diseases.

Definition

ChEBI: 4,5-dianilinophthalimide is phthalimide substituted at the 4- and 5-positions by anilino groups. It has a role as a tyrosine kinase inhibitor and a geroprotector.

Biochem/physiol Actions

DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR.

DAPH Preparation Products And Raw materials

Raw materials

Preparation Products

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DAPH Suppliers

China 23 Switzerland 1 United Kingdom 2 United States 8 Global 34

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145915-58-8, DAPHRelated Search:

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DAPH-1 (DAPH

DAPH/CGP 52411

4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411

1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-

DAPH >=98% (HPLC), solid

CGP52411, 10 mM in DMSO

145915-58-8