4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER

Product Name: 4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
CAS No.: 191102-87-1
Chemical Name: 4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
Synonyms: GGTI-2147;GGTI-2147 (GGTI2147);TUQRZGWNDBXSNP-SANMLTNESA-N;Geranylgeranyl transferase inhibitor-2147;4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER;L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester
CBNumber: CB5766770
Molecular Formula: C28H30N4O3
Formula Weight: 470.56
MOL File: Mol file

More

Less

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Property

Boiling point:: 710.6±60.0 °C(Predicted)
Density: 1.224±0.06 g/cm3(Predicted)
solubility: Soluble in DMSO
pka: 13.22±0.46(Predicted)
form: Solid
Sensitive: Light Sensitive & Hygroscopic

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 345885
Product name: GGTI-2147 - CAS 191102-87-1 - Calbiochem
Purity: A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I).
Packaging: 250μG
Price: $245
Updated: 2024/03/01

Alfa Aesar

Product number: J65022
Product name: GGTI-2147
Packaging: 100microg
Price: $591
Updated: 2021/12/16

TRC

Product number: G368900
Product name: GGTI-2147
Packaging: 5mg
Price: $1470
Updated: 2021/12/16

TRC

Product number: G368900
Product name: GGTI-2147
Packaging: 0.1mg
Price: $115
Updated: 2021/12/16

More

Less

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Chemical Properties,Usage,Production

Uses

GGTI-2147 is an inhibitors of protein geranylgeranyltransferase-I and protein prenylation. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast and increases cytosolic accumulation of Rac1 and elicites significant inhibition of GSIS from INS 832/13 cells.

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Suppliers

Canada 1 China 22 India 1 United Kingdom 1 United States 5 Global 30

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alabiochem Tech.Co., Ltd.

Tel: 0512-58900862 400-0707518
Fax: 0086-512-56765862
Email: sales@alabiochem.com
Country: China
ProdList: 995
Advantage: 59

VDM Biochemicals

Tel: 0330-2528181
Fax: 0330-2528171
Email: sales@vdmbio.com
Country: United States
ProdList: 510
Advantage: 64

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8073
Advantage: 58

Alabiotech Inc.

Tel: 001-619-354-5251
Fax: 001-855-855-6087
Email: sales@alabiotech-e.com
Country: United States
ProdList: 972
Advantage: 60

Alpha Biopharmaceuticals Co., Ltd

Tel: +86-411-39042497 +8613921981412
Fax: 0086-411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 886
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55827
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19915
Advantage: 58

191102-87-1, 4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTERRelated Search:

GGTI-2147

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER

TUQRZGWNDBXSNP-SANMLTNESA-N

GGTI-2147 (GGTI2147)

L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester

Geranylgeranyl transferase inhibitor-2147

191102-87-1

A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I).

Amino Acids & Derivatives, Chiral Reagents, Heterocycles, Inhibitors

Other enzyme inhibitors and activators