N6-CYCLOPENTYLADENOSINE

Product Name: N6-CYCLOPENTYLADENOSINE
CAS No.: 41552-82-3
Chemical Name: N6-CYCLOPENTYLADENOSINE
Synonyms: UK-80882;N-CYCLOPENTYLADENOSINE;N6-CYCLOPENTYLADENOSINE;Adenosine, N-cyclopentyl-;N6-Cyclopentyladenosine,CPA;N(sup 6)-cyclopentyladenosine;N6-Cyclopentyladenosine;N6 Cyclopentyladenosine,N6Cyclopentyladenosine,N-6-Cyclopentyladenosine;(2R,3R,4S,5R)-2-(6-(CyclopentylaMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
CBNumber: CB5779284
Molecular Formula: C15H21N5O4
Formula Weight: 335.36
MOL File: 41552-82-3.mol

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N6-CYCLOPENTYLADENOSINE Property

Melting point:: 78.8 °C
Boiling point:: 673.4±65.0 °C(Predicted)
Density: 1.78±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: H2O: soluble1.7mg/mL
form: solid
pka: 13.12±0.70(Predicted)
color: white to off-white

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Safety

WGK Germany: 3
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C8031
Product name: N6-Cyclopentyladenosine
Purity: solid
Packaging: 25mg
Price: $82.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: C8031
Product name: N6-Cyclopentyladenosine
Purity: solid
Packaging: 100mg
Price: $249
Updated: 2024/03/01

Sigma-Aldrich

Product number: 119135
Product name: Adenosine A1 Receptor Agonist I, CPA - CAS 41552-82-3 - Calbiochem
Packaging: 25MG
Price: $89.9
Updated: 2024/03/01

Cayman Chemical

Product number: 21448
Product name: N6-Cyclopentyladenosine
Purity: ≥99%
Packaging: 10mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21448
Product name: N6-Cyclopentyladenosine
Purity: ≥99%
Packaging: 50mg
Price: $116
Updated: 2024/03/01

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N6-CYCLOPENTYLADENOSINE Chemical Properties,Usage,Production

Uses

N6-Cyclopentyladenosine is a selective Adenosine A1-R agonist with Ki values of 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively and EC50 value of 18600 nM for hA2B. It has also shown its efficacy against organophosphate toxcity.

Uses

N⁶-Cyclopentyladenosine has been used to study its effect on the cavernosal smooth muscle cells from lean and db/db (obesity and type II diabetes caused by a leptin receptor mutation) mice.

Biological Activity

Potent and selective adenosine A 1 receptor agonist (K i values are 2.3, 790 and 43 nM for human A 1 , A 2A and A 3 receptors respectively; EC 50 = 18600 nM for hA 2B ). Centrally active following systemic administration in vivo .

Biochem/physiol Actions

N6-Cyclopentyladenosine (CPA) is an adenosine derivative and a potent A1 adenosine receptor agonist. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures.

storage

Desiccate at +4°C

N6-CYCLOPENTYLADENOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N6-CYCLOPENTYLADENOSINE Suppliers

China 40 Europe 1 Germany 3 Switzerland 2 United Kingdom 3 United States 12 Global 61

3B Pharmachem (Wuhan) International Co.,Ltd.

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Chengdu NoVi Biotechnology Co., Ltd.

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Sigma-Aldrich

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Amadis Chemical Company Limited

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Aikon International Limited

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41552-82-3, N6-CYCLOPENTYLADENOSINERelated Search:

CYCLOPENTYLADENOSINE, 2-CHLORO-N6-[CYCLOPENTYL-2,3,4,5-3H]- (2S)-N6-[2-ENDO-NORBORNYL]ADENOSINE GR 79236 2'-MECCPA 2-CHLORO-N6-CYCLOPENTYLADENOSINE,2-CHLORO-N-CYCLOPENTYLADENOSINE N6-CYCLOPENTYLADENOSINE

N6-CYCLOPENTYLADENOSINE

N-CYCLOPENTYLADENOSINE

N(sup 6)-cyclopentyladenosine

(2R,3R,4S,5R)-2-(6-(CyclopentylaMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol

N<sup>6</sup>-Cyclopentyladenosine

Adenosine, N-cyclopentyl-

N6-Cyclopentyladenosine,CPA

UK-80882

N6 Cyclopentyladenosine,N6Cyclopentyladenosine,N-6-Cyclopentyladenosine

41552-82-3

Adenosine receptor