ChemicalBook > CAS DataBase List > N6-CYCLOPENTYLADENOSINE
N6-CYCLOPENTYLADENOSINE
- Product Name
- N6-CYCLOPENTYLADENOSINE
- CAS No.
- 41552-82-3
- Chemical Name
- N6-CYCLOPENTYLADENOSINE
- Synonyms
- UK-80882;N-CYCLOPENTYLADENOSINE;N6-CYCLOPENTYLADENOSINE;Adenosine, N-cyclopentyl-;N6-Cyclopentyladenosine,CPA;N(sup 6)-cyclopentyladenosine;N6-Cyclopentyladenosine;N6 Cyclopentyladenosine,N6Cyclopentyladenosine,N-6-Cyclopentyladenosine;(2R,3R,4S,5R)-2-(6-(CyclopentylaMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
- CBNumber
- CB5779284
- Molecular Formula
- C15H21N5O4
- Formula Weight
- 335.36
- MOL File
- 41552-82-3.mol
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N6-CYCLOPENTYLADENOSINE Property
- Melting point:
- 78.8 °C
- Boiling point:
- 673.4±65.0 °C(Predicted)
- Density
- 1.78±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble1.7mg/mL
- form
- solid
- pka
- 13.12±0.70(Predicted)
- color
- white to off-white
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Safety
- WGK Germany
- 3
- HS Code
- 29349990
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C8031
- Product name
- N6-Cyclopentyladenosine
- Purity
- solid
- Packaging
- 25mg
- Price
- $82.1
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C8031
- Product name
- N6-Cyclopentyladenosine
- Purity
- solid
- Packaging
- 100mg
- Price
- $249
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 119135
- Product name
- Adenosine A1 Receptor Agonist I, CPA - CAS 41552-82-3 - Calbiochem
- Packaging
- 25MG
- Price
- $89.9
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21448
- Product name
- N6-Cyclopentyladenosine
- Purity
- ≥99%
- Packaging
- 10mg
- Price
- $32
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21448
- Product name
- N6-Cyclopentyladenosine
- Purity
- ≥99%
- Packaging
- 50mg
- Price
- $116
- Updated
- 2024/03/01
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N6-CYCLOPENTYLADENOSINE Chemical Properties,Usage,Production
Uses
N6-Cyclopentyladenosine is a selective Adenosine A1-R agonist with Ki values of 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively and EC50 value of 18600 nM for hA2B. It has also shown its efficacy against organophosphate toxcity.
Uses
N6-Cyclopentyladenosine has been used to study its effect on the cavernosal smooth muscle cells from lean and db/db (obesity and type II diabetes caused by a leptin receptor mutation) mice.
Biological Activity
Potent and selective adenosine A 1 receptor agonist (K i values are 2.3, 790 and 43 nM for human A 1 , A 2A and A 3 receptors respectively; EC 50 = 18600 nM for hA 2B ). Centrally active following systemic administration in vivo .
Biochem/physiol Actions
N6-Cyclopentyladenosine (CPA) is an adenosine derivative and a potent A1 adenosine receptor agonist. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures.
storage
Desiccate at +4°C
N6-CYCLOPENTYLADENOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
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41552-82-3, N6-CYCLOPENTYLADENOSINERelated Search:
CYCLOPENTYLADENOSINE, 2-CHLORO-N6-[CYCLOPENTYL-2,3,4,5-3H]-
(2S)-N6-[2-ENDO-NORBORNYL]ADENOSINE
GR 79236
2'-MECCPA
2-CHLORO-N6-CYCLOPENTYLADENOSINE,2-CHLORO-N-CYCLOPENTYLADENOSINE
N6-CYCLOPENTYLADENOSINE