ChemicalBook > CAS DataBase List > L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
- Product Name
- L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
- CAS No.
- 220701-06-4
- Chemical Name
- L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
- Synonyms
- Fmoc-AENK-NH2;Fmoc-Ala-Glu-Asn-Lys-NH2;L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
- CBNumber
- CB58401114
- Molecular Formula
- C33H43N7O9
- Formula Weight
- 681.75
- MOL File
- 220701-06-4.mol
More
Less
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Property
- Boiling point:
- 1151.3±65.0 °C(Predicted)
- Density
- 1.324±0.06 g/cm3(Predicted)
- storage temp.
- -20°C, protect from light, stored under nitrogen
- solubility
- DMSO: 100 mg/mL (146.68 mM; ultrasonic and warming and heat to 80°C)
- pka
- 4.44±0.10(Predicted)
More
Less
N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0078435
- Product name
- Fmoc-Ala-Glu-Asn-Lys-NH2
- Purity
- 98.04%
- Packaging
- 5mg
- Price
- $135
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0078435
- Product name
- Fmoc-Ala-Glu-Asn-Lys-NH2
- Purity
- 98.04%
- Packaging
- 10mg
- Price
- $235
- Updated
- 2021/12/16
More
Less
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Chemical Properties,Usage,Production
Biological Activity
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing[1]. Fmoc-Ala-Glu-Asn-Lys-NH2 antagonizes APP processing by AEP, whereas other small molecular inhibitors and inactive peptide AEQK were without effect[1].
References
[1]. Zhang Z, et al. Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease. Nat Commun. 2015;6:8762. Published 2015 Nov 9.
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Suppliers
- Tel
- 010-50973130 4009686088
- 3193328036@qq.com
- Country
- China
- ProdList
- 29797
- Advantage
- 68
- Tel
- 0571-87213919
- Fax
- 0571-87213919
- eric@peptidego.com
- Country
- China
- ProdList
- 6347
- Advantage
- 58
- Tel
- +1-2135480471 +1-2135480471
- sales@sarms4muscle.com
- Country
- China
- ProdList
- 10523
- Advantage
- 58
- Tel
- 0510-85629785 18013409632
- Fax
- 0510-85625359
- sales@reading-chemicals.com
- Country
- China
- ProdList
- 14092
- Advantage
- 58
- Tel
- 0571-88211921 13355716090
- Sales@gotopbio.com
- Country
- China
- ProdList
- 2831
- Advantage
- 58
- Tel
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29778
- Advantage
- 58
- Tel
- 0571-88211921 15572296305
- sales4@gotopbio.com
- Country
- China
- ProdList
- 5144
- Advantage
- 58
- Tel
- 0571-87213919 17306812703
- 3007955328@qq.com
- Country
- China
- ProdList
- 5950
- Advantage
- 58
- Tel
- 0571-85350119 15888826472
- 15888826472@163.com
- Country
- China
- ProdList
- 2729
- Advantage
- 58
- Tel
- 19961912513
- sales@hongtide.com
- Country
- China
- ProdList
- 4545
- Advantage
- 58
220701-06-4, L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)Related Search:
FALGPA
KALIOTOXIN
L-659 877
MCA-GLY-LYS-PRO-ILE-LEU-PHE-PHE-ARG-LEU-LYS(DNP)-D-ARG-NH2
Acetyl Pentapeptide-1
Endothelin-1 (human, porcine)
H-CYS-4-ABZ-MET-OH
β-Amyloid (1-38), mouse, rat
L-Proline, L-threonyl-L-histidyl-L-arginyl-L-prolyl-L-prolyl-L-methionyl-L-tryptophyl-L-seryl-L-prolyl-L-valyl-L-tryptophyl-
PEP2M
glutathione monoisopropyl ester
H-TYR-TIC-PHE-PHE-OH