ChemicalBook > CAS DataBase List > trimetozine

trimetozine

Product Name
trimetozine
CAS No.
635-41-6
Chemical Name
trimetozine
Synonyms
V 7;Opalene;PS-2383;PS 2383;NSC-62939;Trioxazin;Sedoxazine;TriMetozin;Trioxazine;Abbott-22370
CBNumber
CB5875528
Molecular Formula
C14H19NO5
Formula Weight
281.3
MOL File
635-41-6.mol
More
Less

trimetozine Property

Melting point:
120-122°
Boiling point:
423.97°C (rough estimate)
Density 
1.1755 (rough estimate)
refractive index 
1.5230 (estimate)
pka
-1.60±0.20(Predicted)
form 
Solid
color 
White to off-white
More
Less

Safety

Toxicity
LD50 oral in rat: 1800mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S570621
Product name
4-(3,4,5-TRIMETHOXYBENZOYL)-MORPHOLINE
Purity
AldrichCPR
Packaging
250MG
Price
$179
Updated
2024/03/01
TRC
Product number
T798200
Product name
Trimetozine
Packaging
5g
Price
$1055
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
62447
Product name
Trimetozine
Packaging
5G
Price
$1460
Updated
2021/12/16
More
Less

trimetozine Chemical Properties,Usage,Production

Originator

Opalene,Theraplix,France,1966

Uses

antiurolithic, depigmentation, radiation protectant

Uses

A sedative with mild tranquilizing effects. It has been used therapeutically in the treatment of anxiety. It is also a metabolite of the antisecretory and antiulcer drug Trithiozine.

Uses

A sedative with mild tranquilizing effects. Trimetozine has been used therapeutically in the treatment of anxiety. It is also a metabolite of the antisecretory and antiulcer drug Trithiozine.

Definition

ChEBI: 4-morpholinyl-(3,4,5-trimethoxyphenyl)methanone is a member of morpholines.

Manufacturing Process

46 g 3,4,5-trimethoxybenzoyl chloride are dissolved in 300 ml anhydrous benzene and 25 g triethylamine and thereafter 19 g anhydrous morpholine are added in small portions with ice-cooling. The solution is boiled for 2 hours under reflux. The precipitate is filtered off, and the solution is washed with dilute sulfuric acid, then with sodium hydrogen carbonate solution and finally with water, and then evaporated. The residual yellow oil soon crystallizes; the crystalline mass of the desired material is taken up with ether, filtered and then recrystallized from 90% ethanol, from which it separates in prisms. It is slightly soluble in water. Yield: 80%. melting point 120°C to 122°C.

Therapeutic Function

Sedative

trimetozine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

trimetozine Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19881
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65

635-41-6, trimetozineRelated Search:


  • Abbott-22370
  • NSC-62939
  • PS 2383
  • PS-2383
  • morpholin-4-yl-(3,4,5-trimethoxyphenyl)methanone
  • morpholino-(3,4,5-trimethoxyphenyl)methanone
  • 4-(3,4,5-TriMethoxybenzoyl)tetrahydro-1,4-oxazine
  • 4-Morpholinyl(3,4,5-triMethoxyphenyl)Methanone
  • N-(3,4,5-TriMethoxybenzoyl)tetrahydro-1,4-oxazine
  • Opalene
  • Sedoxazine
  • Trifenoxazine
  • TriMetozin
  • Trioxazin
  • Trioxazine
  • V 7
  • Methanone, 4-Morpholinyl(3,4,5-triMethoxyphenyl)-
  • trimetozine USP/EP/BP
  • Trimetozine, 10 mM in DMSO
  • 635-41-6
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Neurochemicals
  • Pharmaceuticals