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pimagedine

Product Name
pimagedine
CAS No.
79-17-4
Chemical Name
pimagedine
Synonyms
pimagedine;Aids030897;Aids-030897;Aminate base;1-Aminoguanidine;N-Aminoguanidine;Monoaminoguanidine;Aminoguanidine (ag);Ribavirin Impurity S;Aminoguanidine mordant
CBNumber
CB5875700
Molecular Formula
CH6N4
Formula Weight
74.09
MOL File
79-17-4.mol
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pimagedine Property

Melting point:
182-185 °C (decomp)
Boiling point:
159.5±23.0 °C(Predicted)
Density 
1.72±0.1 g/cm3(Predicted)
refractive index 
1.6660 (estimate)
pka
11.08±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P445105
Product name
Pimagedinehydrochloride
Packaging
10mg
Price
$45
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
18895
Product name
Pimagedine
Purity
98%
Packaging
5mg
Price
$950
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000371
Product name
AMINOGUANIDINE
Purity
95.00%
Packaging
25G
Price
$1146.05
Updated
2021/12/16
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pimagedine Chemical Properties,Usage,Production

Chemical Properties

Aminoguanidine is prepared from hydrazine and aqueous cyanamide solution. Processes based on the reduction of nitroguanidine have no industrial significance.

Chemical Properties

Aminoguanidine [CAS: 79-17-4], CH6N4, Mr 74.09, is a base that forms salts with both inorganic and organic acids. It is soluble in water and ethanol. Free aminoguanidine is stable for only a short time; therefore, it is marketed in the form of its stable salts. Commercially, aminoguanidine is offered as the bicarbonate salt [2582-30-1], a white powder of usually 99 % assay. The water solubility at room temperature is low (< 5 g/L). It is offered by most world-scale hydrazine producers (→Hydrazine). Other salts can be prepared from the bicarbonate by reaction with acid.

Uses

Inhibitor (advanced glycosylation end-product formation).

Definition

ChEBI: Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.

Enzyme inhibitor

This substituted hydrazine (FWhydrochloride = 110.55 g/mol; CAS 79-17-4), also named pimagedine, is a strong inhibitor of diamine oxidases as well as nitric oxide synthase. Note that aminoguanidine also inhibits the formation of advanced glycosylation end-products, reportedly by reacting with and trapping Amadori rearrangement-derived fragmentation products in solution. In view of this property, aminoguanidine has often been used to treat complications associated with chronic diabetes. Target(s): amine oxidase (copper-containing), or diamine oxidase; methylamine dehydrogenase; tryptophan tryptophylquinone enzymes; nitric-oxide synthase; b-fructofuranosidase, or invertase; monoamine oxidase, or amine oxidase; histidine decarboxylase; aldose reductase; catalase; formation of advanced glycosylation end products; adenosylmethionine decarboxylase; arginine deaminase; arginine kinase; aspartate aminotransferase; histamine N-methyltransferase.

pimagedine Preparation Products And Raw materials

Raw materials

Preparation Products

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pimagedine Suppliers

Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-66853366 15920483169
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17944
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9590
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
Macheng jinxin biotechnology co., LTD
Tel
18271582018
Email
1126319697@qq.com
Country
China
ProdList
1630
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9589
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
0551-65418671
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34572
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652,+86-571- 88492614
Email
info@dycnchem.com
Country
CHINA
ProdList
52867
Advantage
58
AFINE CHEMICALS LIMITED
Tel
0571-85134551
Fax
008657185134895
Email
info@afinechem.com
Country
CHINA
ProdList
15377
Advantage
58
Qingdao haohai anjie pharmaceutical technology co., ltd.
Tel
156-6622-8711 18639325623
Email
chen.wanglin@hmgj.group
Country
China
ProdList
1908
Advantage
58

79-17-4, pimagedineRelated Search:


  • Ribavirin Impurity S
  • pimagedine
  • 1-Aminoguanidine
  • Aminate base
  • Amino(imino)methylhydrazine
  • N-Aminoguanidine
  • Aids030897
  • Aids-030897
  • Aminoguanidine (ag)
  • Hydrazinecarboximidamide(9CI)
  • Aminoguanidine mordant
  • HYDRAZINECARBOXIMIDAMIDE (BASE)
  • Monoaminoguanidine
  • 79-17-4
  • HNCNH2NHNH2H2CO3
  • Pharmaceutical Intermediates