sodium 2,2,2-trifluoroethanolate
Application- Product Name
- sodium 2,2,2-trifluoroethanolate
- CAS No.
- 420-87-1
- Chemical Name
- sodium 2,2,2-trifluoroethanolate
- Synonyms
- 2-trifluoroethanolate;Sodium trifluoroethylate;2,2,2-trifluoroethanolate;2,2,2-Trifluoroethoxysodium;sodium 2,2,2-trifluoroethanolate;Sodium-2,2,2-trifluoroethaneolate;2,2,2-Trifluoroethanol, sodium salt;Ethanol,2,2,2-trifluoro-, sodium salt (1:1)
- CBNumber
- CB5891874
- Molecular Formula
- C2H4F3NaO
- Formula Weight
- 124.04
- MOL File
- 420-87-1.mol
sodium 2,2,2-trifluoroethanolate Property
- EPA Substance Registry System
- Ethanol, 2,2,2-trifluoro-, sodium salt (420-87-1)
Safety
- TSCA
- TSCA listed
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H360May damage fertility or the unborn child
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
sodium 2,2,2-trifluoroethanolate Chemical Properties,Usage,Production
Application
sodium 2,2,2-trifluoroethanolate can be used as a pharmaceutical synthesis intermediate.
Synthesis
Preparation of 2-amino-4-dimethylamino-6-trifluoroethoxy-1,3,5-triazine has the following steps: ?? mix melamine and acetone, cooled to 0~10 ?? with an ice bath, dropwise addition of aqueous ammonia solution, dropwise warming to 15~25 ?? stirring reaction 1~3h. ?? cooled the solution to 0~10 ?? with an ice bath, dropwise addition of aqueous dimethylamine, dropwise stirring reaction 1~3h, filtration and water washing Get 2-amino-4-dimethylamino-6-chloro-1,3,5-triazine. ?? Add 2-amino-4-dimethylamino-6-chloro-1,3,5-triazine obtained in step ?? to the organic solution of sodium trifluoroethanol, and reflux the reaction for 2~6h, and then obtain it after post-treatment. The method of the present invention is easy to operate, the intermediate product does not need to be separated, the product yield is high, the purity is high, and it is easy to be produced industrially.
sodium 2,2,2-trifluoroethanolate Preparation Products And Raw materials
Raw materials
Preparation Products
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