ChemicalBook > CAS DataBase List > 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one

1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one

Product Name
1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one
CAS No.
519-98-2
Chemical Name
1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one
Synonyms
N-Methy;Noraminopyrine;noramidopyrine;Methylaminophenazone;Methylaminoantipyrine;Metamizole Impurity C;N-Methylaminophenazone;4-Methylaminophenazone;Monomethylaminoantipyrine;4-(Methylamino)-antipyrine
CBNumber
CB5924116
Molecular Formula
C12H15N3O
Formula Weight
217.27
MOL File
519-98-2.mol
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1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one Property

Melting point:
50-53°C
Boiling point:
324.5±45.0 °C(Predicted)
Density 
1.20±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
4.76±0.20(Predicted)
color 
Pale Yellow to Brown
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Safety

HazardClass 
IRRITANT
Toxicity
LD50 oral in mouse: 7gm/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M285600
Product name
4-MethylaminoAntipyrine
Packaging
10mg
Price
$160
Updated
2021/12/16
Usbiological
Product number
016478
Product name
4-Methylamino Antipyrine
Packaging
10mg
Price
$446
Updated
2021/12/16
TRC
Product number
M285600
Product name
4-MethylaminoAntipyrine
Packaging
100mg
Price
$1295
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0163993
Product name
1,5-DIMETHYL-4-(METHYLAMINO)-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOL-3-ONE HYDROCHLORIDE
Purity
95.00%
Packaging
5G
Price
$1328.25
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0163993
Product name
1,5-DIMETHYL-4-(METHYLAMINO)-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOL-3-ONE HYDROCHLORIDE
Purity
95.00%
Packaging
1G
Price
$750.75
Updated
2021/12/16
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1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one Chemical Properties,Usage,Production

Chemical Properties

Pale Orange Low Melting Waxy Solid

Uses

A metabolite of Dipyrone, a nonsteroidal anti-inflammatory drug.

Definition

ChEBI: A member of the class of pyrazoles that is antipyrine substituted at C-4 by a methylamino group. It is a metabolite of aminopyrine and of metamizole.

in vivo

The aim of this study is to assess the pharmacokinetics of its active metabolites 4-Methylamino antipyrine in male piglets after a single intramuscular injection of Metamizole. Eight healthy male piglets are administered Metamizole (100 mg/kg) intramuscularly. 4-Methylamino antipyrine plasma concentrations are quantitatively detectable from 0.25 to 48 h. The average maximum concentrations of 4-Methylamino antipyrine is of 47.59 mg/mL. The average half-lives is 8.57 h for 4-Methylamino antipyrine[1].

1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one Preparation Products And Raw materials

Raw materials

N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide 4-Aminoantipyrine

Preparation Products

AMMONIUM ALGINATE
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1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one Suppliers

Canada 1 China 104 Germany 1 India 7 United States 14 Global 127
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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021-50135380
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NovoChemy Ltd.
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0755-28363542
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Sichuan Wei Keqi Biological Technology Co., Ltd.
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028-81700200 18116577057
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028-81705658
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3003855609@qq.com
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China
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Jiaxing Novartis Chemical Co., Ltd.
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18957373295
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View Lastest Price from 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one 519-98-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-13
Shaanxi Dideu New Materials Co. Ltd
Product
1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one 519-98-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-15
Career Henan Chemical Co
Product
1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one 519-98-2
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

519-98-2, 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one Related Search:

4-ACETAMIDOANTIPYRINE AMINOPROPYLON Aminopyrine Isopyrin hydrochloride Metamizole Sodium Monohydrate Antipyrine (((2,3-DIMETHYL-5-OXO-1-PHENYL-3-PYRAZOLIN-4-YL)AMINO)METHYLENE)METHANE-1,1-DICARBONITRILE [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonic acid 4-(DIMETHYL-13C 2-AMINO)ANTIPYRINE 4,4'-[methylenebis(methylimino)]bis[1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one] N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide 2-CHLORO-N-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)ACETAMIDE ETHYL N-(4-ANTIPYRYL)CARBAMATE 3-((2,3-DIMETHYL-5-OXO-1-PHENYL(3-PYRAZOLIN-4-YL))AMINO)-2-((4-METHYLPHENYL)SULFONYL)PROP-2-ENENITRILE 1-(2,3-DIMETHYL-5-OXO-1-PHENYL(3-PYRAZOLIN-4-YL)-3-(3-(TRIFLUOROMETHYL)PHENYL)UREA AKOS BBS-00001838 2-((2,3-DIMETHYL-5-OXO-1-PHENYL(3-PYRAZOLIN-4-YL))AMINO)-2-(1,3-DIOXOINDAN-2-YLIDENE)ETHANENITRILE 2,3-DIMETHYL-4-((3-OXO-5-PHENYLCYCLOHEX-1-ENYL)AMINO)-1-PHENYL-3-PYRAZOLIN-5-ONE

  • 2-(1-cyclohexa-2,4-dienyl)-1,5-dimethyl-4-(methylamino)-3-pyrazolone
  • noramidopyrine
  • 4-(Methylamino)-antipyrine
  • 2,3-Dimethyl-4-methylamino-1-phenyl-3-pyrazolin-5-one
  • Methylaminoantipyrine
  • Monomethylaminoantipyrine
  • Noraminopyrine
  • 1,5-Dimethyl-4-(methylamino)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one hydrochloride
  • N-Methylaminophenazone
  • MetaMizole IMpurity C (4-MethylaMinoantipyrine)
  • 3H-pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(methylamino)
  • 1,5-dimethyl-4-(methylamino)-2-phenyl-pyrazol-3-one
  • 1,5-dimethyl-4-(methylamino)-2-phenylpyrazol-3-one
  • 4-(N-Methyl)-aminoantipyrine
  • 1,5-dimethyl-4-(methylamino)-2-phenyl-1,2-dihydropyrazol-3-one
  • 1,5-dimethyl-4-methylamino-2-phenyl-3-pyrazolone
  • 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-
  • 4-Methylaminophenazone
  • 4-Monomethylaminoantipyrine
  • 4-Monomethylaminophenazone
  • ANTIPYRINE, 4-(METHYLAMINO)-
  • Methylaminophenazone
  • N-Methy
  • Metamizole Sodium Impurity 3（Minocycline EP Impurity C）
  • Metamizole Sodium Impurity 3（Metamizole Sodium EP Impurity C）
  • 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one
  • Metamizole Impurity C
  • Metamizole sodium EP Impurity C
  • Metamizole Impurity CQ: What is Metamizole Impurity C Q: What is the CAS Number of Metamizole Impurity C Q: What is the storage condition of Metamizole Impurity C Q: What are the applications of Metamizole Impurity C
  • Metamizole EP Impurity C 1,5-dimethyl-4-(methylamino)-2-phenyl-2,3-dihydro-1H-pyrazol- 3-one
  • 4-Methylamino antipyrine, 10 mM in DMSO
  • 1,5-dimethyl-4-methylamino-2-phenylpyrazolin-3-one
  • 4-(Methylamino)antipyrine 100 μg/mL in Acetonitrile
  • 519-98-2
  • 21727
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals