Synthesis
ChemicalBook > CAS DataBase List > 1H-indole-3-propylamine

1H-indole-3-propylamine

Synthesis
Product Name
1H-indole-3-propylamine
CAS No.
6245-89-2
Chemical Name
1H-indole-3-propylamine
Synonyms
Einecs 228-361-1;1H-indole-3-propylamine;1H-Indole-3-propanamine;N-propyl-1H-indol-3-amine;1H-Indole-3-propan-1-amine;(1H-Indol-3-yl)-1-propanamine
CBNumber
CB5927122
Molecular Formula
C11H14N2
Formula Weight
174.24
MOL File
6245-89-2.mol
More
Less

1H-indole-3-propylamine Property

Melting point:
64 °C
Boiling point:
353.7±25.0 °C(Predicted)
Density 
1.125±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
17.29±0.30(Predicted)
More
Less

Safety

Risk Statements 
20/21/22-37/38-48
Safety Statements 
22-26-7/8-36/37/39-45
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
I633913
Product name
3-(Indol-3-yl)propanamine
Packaging
50mg
Price
$95
Updated
2021/12/16
TRC
Product number
I633913
Product name
3-(Indol-3-yl)propanamine
Packaging
250mg
Price
$250
Updated
2021/12/16
AK Scientific
Product number
J55003
Product name
(1H-Indol-3-yl)-1-propanamine
Packaging
1g
Price
$135
Updated
2021/12/16
Matrix Scientific
Product number
072031
Product name
(1H-Indol-3-yl)-1-propanamine
Purity
95+%
Packaging
1g
Price
$440
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0074502
Product name
3-(1H-INDOL-3-YL)-1-PROPANAMINE
Purity
95.00%
Packaging
1G
Price
$925.31
Updated
2021/12/16
More
Less

1H-indole-3-propylamine Chemical Properties,Usage,Production

Synthesis

A solution of LAH (1.0 M in ether, 36.5 mL, 36.5 mmol) was cooled to 0 °C, and  a solution of the cyanoethyl indole (2.78 g, 16.3 mmol) was added slowly. Then, the solution was heated at reflflux for 3 h. It was cooled to 0 °C and quenched by dropwise addition of water (20 mL) followed by 1 N sodium hydroxide (40 mL). The phases were separated, and the aqueous phase was extracted with ether. The combined organic phases were washed with brine and then dried (potassium hydroxide). Evaporation of the solvent gave 2.6 g (92%) of homotryptamine as a yellow oil, which solidifified on standing. The hydrochloride was prepared by dissolving the amine in a minimum of ethanol and then a saturated solution of hydrogen chloride in ether was added until no additional salt formation was observed. The hydrochloride was recrystallized from ethanol.

Reference: Kuehne, M. E.; Cowen, S. D.; Xu, F.; Borman, L. S. J. Org. Chem. 2001, 66, 5303–5316.

Chemical Properties

Light yellow powder

1H-indole-3-propylamine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1H-indole-3-propylamine Suppliers

Shanghai Anya Pharmaceutical Technology Co., LTD
Tel
19106202509
Fax
QQ 3626423147
Email
3626423147@qq.com
Country
China
ProdList
995
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Nanjing Norris-Pharm Technology Co., Ltd
Tel
13901585132
Fax
+86-25-52131256
Email
799750417@qq.com
Country
China
ProdList
8888
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12742
Advantage
55
Shanghai Jiyi Biological Technology Co., LTD
Tel
021-54135696 18516235431
Fax
50815371
Email
shgegenetech@163.com
Country
China
ProdList
986
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12357
Advantage
58
Shanghai Synchem Pharma Co., ltd
Tel
021-61984905-1 18016477331
Email
synchempharma@aliyun.com
Country
China
ProdList
6454
Advantage
55
Shanghai Kahn Pharmaceutical Co., Ltd.
Tel
17701870669
Fax
021-34979681
Email
sales@kahn-pharm.com
Country
China
ProdList
1614
Advantage
55