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ETIROXATE

Product Name
ETIROXATE
CAS No.
17365-01-4
Chemical Name
ETIROXATE
Synonyms
CG-63;CG-635;ETIROXATE;DL-a-Methyl-thyroxine Ethyl Ester;DL-α-Methyl-thyroxine Ethyl Ester;Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester;O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-α-methyl-DL-tyrosine Ethyl Ester;O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-a-methyl-DL-tyrosine Ethyl Ester;(±)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-2-methylpropionic acid ethyl ester
CBNumber
CB5985045
Molecular Formula
C18H17I4NO4
Formula Weight
818.935
MOL File
17365-01-4.mol
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ETIROXATE Property

Melting point:
149-1510C
Boiling point:
563.7±50.0 °C(Predicted)
Density 
2.321±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO, Methanol
form 
Solid
pka
6.89±0.25(Predicted)
color 
Tan
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E932980
Product name
Etiroxate
Packaging
5mg
Price
$90
Updated
2021/12/16
TRC
Product number
E932980
Product name
Etiroxate
Packaging
10mg
Price
$110
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000557
Product name
ETIROXATE
Purity
95.00%
Packaging
5MG
Price
$311.3
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000557
Product name
ETIROXATE
Purity
95.00%
Packaging
10MG
Price
$704.55
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
10176
Product name
Etiroxate
Packaging
10mg
Price
$860
Updated
2021/12/16
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ETIROXATE Chemical Properties,Usage,Production

Chemical Properties

Tan Solid

Originator

Skleronorm,Gruenenthal,W. Germany,1977

Uses

Derivative of thyroxine. Antilipemic.

Definition

ChEBI: Etiroxate is an aromatic ether.

Manufacturing Process

7.91 g of α-methyl thyroxine are suspended in 150 cc of ethanol. While heating, the solution is saturated with dry hydrogen chloride. Thereafter, the solvent is distilled off at reduced pressure. The residue is dissolved in a mixture of ethanol and water (1:1). Adding a 5% solution of sodium hydrogen carbonate in water, the ethyl ester of α-methyl thyroxine precipitates; melting point: 156°C to 157°C after recrystallization from ethanol. The yield is 6.05 g, i.e., 74% of the theoretical yield.

Therapeutic Function

Antihyperlipoproteinemic

ETIROXATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETIROXATE Suppliers

Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42

17365-01-4, ETIROXATERelated Search:


  • CG-63
  • DL-a-Methyl-thyroxine Ethyl Ester
  • O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-a-methyl-DL-tyrosine Ethyl Ester
  • (±)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-2-methylpropionic acid ethyl ester
  • CG-635
  • DL-α-Methyl-thyroxine Ethyl Ester
  • O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-α-methyl-DL-tyrosine Ethyl Ester
  • ETIROXATE
  • Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester
  • 17365-01-4
  • C18H17I4NO4
  • Intermediates & Fine Chemicals
  • Pharmaceuticals