ETIROXATE

Product Name: ETIROXATE
CAS No.: 17365-01-4
Chemical Name: ETIROXATE
Synonyms: CG-63;CG-635;ETIROXATE;DL-a-Methyl-thyroxine Ethyl Ester;DL-α-Methyl-thyroxine Ethyl Ester;Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester;O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-α-methyl-DL-tyrosine Ethyl Ester;O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-a-methyl-DL-tyrosine Ethyl Ester;(±)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-2-methylpropionic acid ethyl ester
CBNumber: CB5985045
Molecular Formula: C18H17I4NO4
Formula Weight: 818.935
MOL File: 17365-01-4.mol

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ETIROXATE Property

Melting point:: 149-1510C
Boiling point:: 563.7±50.0 °C(Predicted)
Density: 2.321±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO, Methanol
form: Solid
pka: 6.89±0.25(Predicted)
color: Tan

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: E932980
Product name: Etiroxate
Packaging: 5mg
Price: $90
Updated: 2021/12/16

TRC

Product number: E932980
Product name: Etiroxate
Packaging: 10mg
Price: $110
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0000557
Product name: ETIROXATE
Purity: 95.00%
Packaging: 5MG
Price: $311.3
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0000557
Product name: ETIROXATE
Purity: 95.00%
Packaging: 10MG
Price: $704.55
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 10176
Product name: Etiroxate
Packaging: 10mg
Price: $860
Updated: 2021/12/16

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ETIROXATE Chemical Properties,Usage,Production

Chemical Properties

Tan Solid

Originator

Skleronorm,Gruenenthal,W. Germany,1977

Uses

Derivative of thyroxine. Antilipemic.

Definition

ChEBI: Etiroxate is an aromatic ether.

Manufacturing Process

7.91 g of α-methyl thyroxine are suspended in 150 cc of ethanol. While heating, the solution is saturated with dry hydrogen chloride. Thereafter, the solvent is distilled off at reduced pressure. The residue is dissolved in a mixture of ethanol and water (1:1). Adding a 5% solution of sodium hydrogen carbonate in water, the ethyl ester of α-methyl thyroxine precipitates; melting point: 156°C to 157°C after recrystallization from ethanol. The yield is 6.05 g, i.e., 74% of the theoretical yield.

Therapeutic Function

Antihyperlipoproteinemic

ETIROXATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETIROXATE Suppliers

Canada 1 China 14 India 1 United Kingdom 1 United States 4 Global 21

United States Biological

Tel: --
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Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Medical Isotopes

Tel: --
Fax: --
Email: stohler@medicalisotopes.com
Country: United States
ProdList: 6181
Advantage: 68

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

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Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

17365-01-4, ETIROXATERelated Search:

2-Amino-2-methyl-propionic acid ethyl ester hydrochloride 3,5-DIIODO-DL-THYRONINE 1-METHOXY-3,5-DIIODOBENZENE ETHYL (S)-2-AMINO-2-METHYLBUTYRATE 3,3',5-TRIIODOTHYROPROPIONIC ACID 3 5-DIIODOTHYROPROPIONIC ACID DL-ALPHA-METHYLTYROSINE DL-THYROXINE 2 6-DIIODOHYDROQUINONE ETIROXATE

CG-63

DL-a-Methyl-thyroxine Ethyl Ester

O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-a-methyl-DL-tyrosine Ethyl Ester

(±)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-2-methylpropionic acid ethyl ester

CG-635

DL-α-Methyl-thyroxine Ethyl Ester

O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-α-methyl-DL-tyrosine Ethyl Ester

ETIROXATE

Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester

17365-01-4

C18H17I4NO4

Intermediates & Fine Chemicals

Pharmaceuticals